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Protein

Protein phosphatase PTC7 homolog fig

Gene

fig

Organism
Drosophila ananassae (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarityCurated, Mn2+By similarityCurated

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi102 – 1021Manganese 1By similarity
Metal bindingi102 – 1021Manganese 2By similarity
Metal bindingi103 – 1031Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi247 – 2471Manganese 2By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein phosphatase PTC7 homolog fig
Alternative name(s):
Fos intronic gene protein (EC:3.1.3.16)
Gene namesi
Name:figBy similarity
ORF Names:GF22865
OrganismiDrosophila ananassae (Fruit fly)
Taxonomic identifieri7217 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000007801 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0099859. Dana\GF22865.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 332332Protein phosphatase PTC7 homolog figPRO_0000377395Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi7217.FBpp0126057.

Structurei

3D structure databases

ProteinModelPortaliB3MTI8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini70 – 325256PPM-type phosphatasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Sequence Analysis
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0631.
InParanoidiB3MTI8.
KOiK17508.
OrthoDBiEOG7DRJ3F.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
[Graphical view]
PfamiPF07228. SpoIIE. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3MTI8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPTMMSNWP GFINRFVRQV RHPLDFRRPY RITGFPDNLS PLGYFGQTKQ
60 70 80 90 100
YARAAQEPYL VTVVQGRSKK PCSPRERANR RFGEDSWFVS STPRAEVLGV
110 120 130 140 150
ADGVGGWRDM GVDAGRFAKE LMGCCCGRSE QEDFDGRNPR SLLVSSYQEL
160 170 180 190 200
KDRDDPVVGS STACVVAMHR RDLTLYTANL GDSGFMVLRN GRVMHRSEEQ
210 220 230 240 250
THDFNTPFQL TVAPSHKLDS VHCDGPEKAA VSRHPLAPGD LVLLATDGLF
260 270 280 290 300
DNLPESMLLE MLRKFHGVRD EKELQDAANQ VVEKARELSM NASFPSPFAV
310 320 330
KARANNISYS GGGKPDDITL ILASVEVPKV HR
Length:332
Mass (Da):37,041
Last modified:September 2, 2008 - v1
Checksum:i575F9102003159D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902623 Genomic DNA. Translation: EDV30578.1.
RefSeqiXP_001964782.1. XM_001964746.1.

Genome annotation databases

EnsemblMetazoaiFBtr0127565; FBpp0126057; FBgn0099859.
GeneIDi6505517.
KEGGidan:Dana_GF22865.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902623 Genomic DNA. Translation: EDV30578.1.
RefSeqiXP_001964782.1. XM_001964746.1.

3D structure databases

ProteinModelPortaliB3MTI8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7217.FBpp0126057.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0127565; FBpp0126057; FBgn0099859.
GeneIDi6505517.
KEGGidan:Dana_GF22865.

Organism-specific databases

FlyBaseiFBgn0099859. Dana\GF22865.

Phylogenomic databases

eggNOGiCOG0631.
InParanoidiB3MTI8.
KOiK17508.
OrthoDBiEOG7DRJ3F.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
[Graphical view]
PfamiPF07228. SpoIIE. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 14024-0371.13Imported.

Entry informationi

Entry nameiPTC71_DROAN
AccessioniPrimary (citable) accession number: B3MTI8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: September 2, 2008
Last modified: April 1, 2015
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.