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Protein

Delta-like protein

Gene

Dana\GF22944

Organism
Drosophila ananassae (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Putative Notch ligand involved in the mediation of Notch signaling.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Delta-like proteinUniRule annotation
Gene namesi
Name:Dana\GF22944Imported
ORF Names:Dana_GF22944Imported, GF22944Imported
OrganismiDrosophila ananassae (Fruit fly)Imported
Taxonomic identifieri7217 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000007801 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0099938. Dana\GF22944.

Subcellular locationi

  • Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1258 – 1281HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi7217.FBpp0126136.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini251 – 295DSLInterPro annotationAdd BLAST45
Domaini296 – 329EGF-likeInterPro annotationAdd BLAST34
Domaini363 – 401EGF-likeInterPro annotationAdd BLAST39
Domaini516 – 552EGF-likeInterPro annotationAdd BLAST37
Domaini604 – 640EGF-likeInterPro annotationAdd BLAST37
Domaini642 – 677EGF-likeInterPro annotationAdd BLAST36
Domaini679 – 715EGF-likeInterPro annotationAdd BLAST37
Domaini717 – 752EGF-likeInterPro annotationAdd BLAST36
Domaini796 – 832EGF-likeInterPro annotationAdd BLAST37
Domaini834 – 870EGF-likeInterPro annotationAdd BLAST37
Domaini872 – 912EGF-likeInterPro annotationAdd BLAST41
Domaini914 – 950EGF-likeInterPro annotationAdd BLAST37
Domaini952 – 988EGF-likeInterPro annotationAdd BLAST37

Keywords - Domaini

EGF-like domainUniRule annotationSAAS annotation, RepeatUniRule annotationSAAS annotation, SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1217. Eukaryota.
ENOG410XP6K. LUCA.
InParanoidiB3MT39.
KOiK06052.
OMAiMPGAPDK.
OrthoDBiEOG091G0A88.
PhylomeDBiB3MT39.

Family and domain databases

InterProiIPR001774. DSL.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_.
IPR026219. Jagged/Serrate.
IPR011651. Notch_ligand_N.
IPR001007. VWF_dom.
[Graphical view]
PfamiPF01414. DSL. 1 hit.
PF00008. EGF. 7 hits.
PF12661. hEGF. 2 hits.
PF07657. MNNL. 1 hit.
[Graphical view]
PRINTSiPR02059. JAGGEDFAMILY.
SMARTiSM00051. DSL. 1 hit.
SM00181. EGF. 14 hits.
SM00179. EGF_CA. 9 hits.
SM00215. VWC_out. 1 hit.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 7 hits.
PS51051. DSL. 1 hit.
PS00022. EGF_1. 14 hits.
PS01186. EGF_2. 8 hits.
PS50026. EGF_3. 12 hits.
PS01187. EGF_CA. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3MT39-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRMFRKHFR RKSTSTSGQS TAIAIATATS ASAATSPATS DSLRMSKKTM
60 70 80 90 100
ATKRQRPRHR ELSALPSPIS DCRSLKSACN LIALILILLV HKISAAGNFE
110 120 130 140 150
LEILEISNTN SHLLNGYCCG MPSELRATKT MGCSPCTTAF RLCLKEYQTT
160 170 180 190 200
EQGASISTGC SFGNSTTKIL GGSSFVLSDP GVGAIVLPFT FRWTKSFTLI
210 220 230 240 250
LQALDMYNTS YPDSERLIEE TSYSGVILPS PEWKTLDHIG RNARITYRVR
260 270 280 290 300
VQCAVTYYNT TCTTFCRSRD DQFGHYACGS EGQKLCLNGW QGVNCEEAIC
310 320 330 340 350
KTGCDPVHGK CDRPGECECR PGWRGPLCNE CMVYPGCKHG SCNGSAWKCV
360 370 380 390 400
CDTNWGGILC DQDLNYCGTH EPCKHGGTCE NTAPDQYRCT CAEGLSGAQC
410 420 430 440 450
EIVEHPCATQ PCRNGGTCTL KPMNATRPPM YRNMRGMGSL GRAMSPRDSI
460 470 480 490 500
SKLAHLRDAM LALNGKNSSS GSGPDAGSGS ISRPIALFSS SQLPPPAAEF
510 520 530 540 550
TCGCANGWTG PTCEINIDEC AGGPCEHGGT CVDLVGGFRC ECPPEWRGDI
560 570 580 590 600
CQEDVNECEA PHAPGLQANS LLTTTATAII GSNLTSSELL AALTSAVASS
610 620 630 640 650
ASSAATAAAI GPCINARECR NLPGSFSCIC LEGWGGPTCA ENLDDCMGQC
660 670 680 690 700
RNGASCIDLV NDYRCACAPG YTGRDCEIDI DECATSPCRN GGECVDMVAK
710 720 730 740 750
FNCICPLGYF GSLCEEAKDH CASSPCLQGH CLNTPGSYYC HCPPDRAGKH
760 770 780 790 800
CEQLRPLCSQ PPCNEGCFAN VSLATAATTT TSDSEATKTG TATTTTMTTP
810 820 830 840 850
SGLPCSGHGS CEMSDVGTFC KCHVGHTGTF CEHNLNECSP NPCRNGGICL
860 870 880 890 900
DGDGDFTCEC MSGWTGKRCS ERATGCYAGQ CQNGGTCMPG APDKALQPHC
910 920 930 940 950
RCAPGWTGLF CDEAIDQCRG QPCHNGGTCE SGTGWFRCVC AQGFSGPDCR
960 970 980 990 1000
INVNECSPQP CQGGATCIDG IGGYSCICPP GRHGLRCEIL MSDPKSACLN
1010 1020 1030 1040 1050
ITNTASPYAA LNQSQNWLDI ALTGRSDDDD HCNACICENG TSKCTNLWCG
1060 1070 1080 1090 1100
LPNCYKLDPL SKSSNLSGVC KQHEVCVPAL SESCLSPPCN VRGDCRALEP
1110 1120 1130 1140 1150
SRRVAPPNLP AKSSCWPNQA AVNENCARLT ILLDLERVGR GASVEGLCSL
1160 1170 1180 1190 1200
VRVLLAAQLV KQPGFSNGQE TGQLMVLCDL KTGTNDTVEL TVSSSKLNDP
1210 1220 1230 1240 1250
QLPVAVGLLG ELLSSRQLNG IQRRKELELQ HAKLAALTSI LEVKLETARV
1260 1270 1280 1290 1300
ADGSGHSLLI GVLCGVFIVL VGFSVFISLY WKQRMAYRSN SGMNLTPSLD
1310 1320 1330 1340 1350
ALRHEEEKSN NLQNEENLRR YTNPLKGSTS SLRATTGMEL SLNPAPELAA
1360 1370 1380 1390 1400
SAASSSALHR SQPLFPPCDF ERELDSSTGL KQAHKRSSQI LLHKTQNSDM
1410 1420 1430 1440
RKNTVGSLDS PRKDFGKRSI NCKSLPPPAD EGADVLATTV MV
Length:1,442
Mass (Da):153,709
Last modified:September 2, 2008 - v1
Checksum:i8A9EE77444A1686F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902623 Genomic DNA. Translation: EDV30429.1.
RefSeqiXP_001964633.1. XM_001964597.2.

Genome annotation databases

EnsemblMetazoaiFBtr0127644; FBpp0126136; FBgn0099938.
GeneIDi6505593.
KEGGidan:Dana_GF22944.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902623 Genomic DNA. Translation: EDV30429.1.
RefSeqiXP_001964633.1. XM_001964597.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7217.FBpp0126136.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0127644; FBpp0126136; FBgn0099938.
GeneIDi6505593.
KEGGidan:Dana_GF22944.

Organism-specific databases

FlyBaseiFBgn0099938. Dana\GF22944.

Phylogenomic databases

eggNOGiKOG1217. Eukaryota.
ENOG410XP6K. LUCA.
InParanoidiB3MT39.
KOiK06052.
OMAiMPGAPDK.
OrthoDBiEOG091G0A88.
PhylomeDBiB3MT39.

Family and domain databases

InterProiIPR001774. DSL.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_.
IPR026219. Jagged/Serrate.
IPR011651. Notch_ligand_N.
IPR001007. VWF_dom.
[Graphical view]
PfamiPF01414. DSL. 1 hit.
PF00008. EGF. 7 hits.
PF12661. hEGF. 2 hits.
PF07657. MNNL. 1 hit.
[Graphical view]
PRINTSiPR02059. JAGGEDFAMILY.
SMARTiSM00051. DSL. 1 hit.
SM00181. EGF. 14 hits.
SM00179. EGF_CA. 9 hits.
SM00215. VWC_out. 1 hit.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 7 hits.
PS51051. DSL. 1 hit.
PS00022. EGF_1. 14 hits.
PS01186. EGF_2. 8 hits.
PS50026. EGF_3. 12 hits.
PS01187. EGF_CA. 5 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB3MT39_DROAN
AccessioniPrimary (citable) accession number: B3MT39
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: November 30, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.