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Protein

Serine/threonine-protein phosphatase Pgam5, mitochondrial

Gene

Pgam5

Organism
Drosophila ananassae (Fruit fly)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity (By similarity).By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase Pgam5, mitochondrialBy similarity (EC:3.1.3.16)
Alternative name(s):
Phosphoglycerate mutase family member 5 homologBy similarity
Gene namesi
Name:Pgam5By similarity
ORF Names:GF21073
OrganismiDrosophila ananassae (Fruit fly)
Taxonomic identifieri7217 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000007801 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0098078 Dana\GF21073

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 23HelicalSequence analysisAdd BLAST17

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003907031 – 289Serine/threonine-protein phosphatase Pgam5, mitochondrialAdd BLAST289

Expressioni

Gene expression databases

BgeeiFBgn0098078

Interactioni

Subunit structurei

Interacts with Pk92B/ASK1.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7217.FBpp0124265

Structurei

3D structure databases

ProteinModelPortaliB3MR30
SMRiB3MR30
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4609 Eukaryota
ENOG410XXCQ LUCA
InParanoidiB3MR30
KOiK15637
OMAiHLTNRIP
OrthoDBiEOG091G0DEJ
PhylomeDBiB3MR30

Family and domain databases

CDDicd07067 HP_PGM_like, 1 hit
Gene3Di3.40.50.1240, 1 hit
InterProiView protein in InterPro
IPR013078 His_Pase_superF_clade-1
IPR029033 His_PPase_superfam
PfamiView protein in Pfam
PF00300 His_Phos_1, 2 hits
SMARTiView protein in SMART
SM00855 PGAM, 1 hit
SUPFAMiSSF53254 SSF53254, 1 hit

Sequencei

Sequence statusi: Complete.

B3MR30-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKLSSLVCG AGAGLAAFYL SRLRDPQKAA HSSWTNSEKP VDACGLWDSN
60 70 80 90 100
WDCRDPRLMV RPLKNTQPEE ENRFNADLEK AKPKKARHII LVRHGEYLDV
110 120 130 140 150
GESDATHHLT ERGRKQAQFT GQRLSELGIQ WDKVIASTMV RAQETADIIL
160 170 180 190 200
KEIKYDKEKV VNCVYLREGA PIPPQPPVGH WKPEASQFYR DGARIEAAFR
210 220 230 240 250
RYFHRAYPDQ DKESYTLIVG HGNVIRYFVC RALQFPPEGW LRISINHASI
260 270 280
TWLTISPSGN VSIKYLGDSG FMPVQYLTNR IPRDAKNVV
Length:289
Mass (Da):32,959
Last modified:September 2, 2008 - v1
Checksum:iD477D3D60F0A71E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902622 Genomic DNA Translation: EDV34235.1
RefSeqiXP_001963786.1, XM_001963750.2

Genome annotation databases

EnsemblMetazoaiFBtr0125773; FBpp0124265; FBgn0098078
GeneIDi6503762
KEGGidan:Dana_GF21073

Similar proteinsi

Entry informationi

Entry nameiPGAM5_DROAN
AccessioniPrimary (citable) accession number: B3MR30
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 19, 2010
Last sequence update: September 2, 2008
Last modified: March 28, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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