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Protein

Mitogen-activated protein kinase

Gene

Dana\GF14126

Organism
Drosophila ananassae (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseSAAS annotation, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Mitogen-activated protein kinaseSAAS annotation (EC:2.7.11.24SAAS annotation)
Gene namesi
Name:Dana\GF14126Imported
ORF Names:Dana_GF14126Imported, GF14126Imported
OrganismiDrosophila ananassae (Fruit fly)Imported
Taxonomic identifieri7217 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000007801 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0091153. Dana\GF14126.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi7217.FBpp0117318.

Structurei

3D structure databases

ProteinModelPortaliB3MPN7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini23 – 319297Protein kinaseInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains protein kinase domain.SAAS annotation

Phylogenomic databases

eggNOGiENOG410XSHI. LUCA.
KOG0665. Eukaryota.
InParanoidiB3MPN7.
KOiK04440.
OMAiDCLFPAD.
OrthoDBiEOG7PCJGV.
PhylomeDBiB3MPN7.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR008351. MAPK_JNK.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR01772. JNKMAPKINASE.
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS01351. MAPK. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3MPN7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKHKMAAQH QHYTVEVGDT NFTIHSRYIN LRPIGSGAQG IVCAAYDTVT
60 70 80 90 100
EQNVAIKKLS RPFQNVTHAK RAYREFKLMK LVNHKNIIGL LNAFTPQRNL
110 120 130 140 150
EEFQDVYLVM ELMDANLCQV IQMDLDHDRM SYLLYQMLCG IKHLHSAGII
160 170 180 190 200
HRDLKPSNIV VKADCTLKIL DFGLARTAGT TFMMTPYVVT RYYRAPEVIL
210 220 230 240 250
GMGYTENVDI WSVGCIMGEM IRGGVLFPGT DHIDQWNKII EQLGTPSPSF
260 270 280 290 300
MQRLQPTVRN YVENRPRYTG YSFDRLFPDG LFPSDNNQSS RRKASDARNL
310 320 330 340 350
LSKMLVIDPE QRISVDEALK HEYINVWYDA EEVDAPAPEP YDHSVDEREH
360 370
TVEQWKELIY EEVMDYEAHN TNNRTR
Length:376
Mass (Da):43,455
Last modified:January 20, 2016 - v2
Checksum:iFABEB7A95119DA90
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902620 Genomic DNA. Translation: EDV32285.2.
RefSeqiXP_001963064.1. XM_001963028.1.

Genome annotation databases

EnsemblMetazoaiFBtr0118826; FBpp0117318; FBgn0091153.
GeneIDi6496954.
KEGGidan:Dana_GF14126.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902620 Genomic DNA. Translation: EDV32285.2.
RefSeqiXP_001963064.1. XM_001963028.1.

3D structure databases

ProteinModelPortaliB3MPN7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7217.FBpp0117318.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0118826; FBpp0117318; FBgn0091153.
GeneIDi6496954.
KEGGidan:Dana_GF14126.

Organism-specific databases

FlyBaseiFBgn0091153. Dana\GF14126.

Phylogenomic databases

eggNOGiENOG410XSHI. LUCA.
KOG0665. Eukaryota.
InParanoidiB3MPN7.
KOiK04440.
OMAiDCLFPAD.
OrthoDBiEOG7PCJGV.
PhylomeDBiB3MPN7.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR008351. MAPK_JNK.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR01772. JNKMAPKINASE.
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS01351. MAPK. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 14024-0371.13Imported.

Entry informationi

Entry nameiB3MPN7_DROAN
AccessioniPrimary (citable) accession number: B3MPN7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: January 20, 2016
Last modified: January 20, 2016
This is version 48 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.