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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

Gpdh

Organism
Drosophila ananassae (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei98NADUniRule annotation1
Binding sitei121SubstrateUniRule annotation1
Binding sitei155NAD; via amide nitrogenUniRule annotation1
Active sitei206Proton acceptorUniRule annotation1
Binding sitei270NADUniRule annotation1
Binding sitei297NAD; via amide nitrogenUniRule annotation1
Binding sitei299NADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi11 – 16NADUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
Name:GpdhImported
Synonyms:Dana\GpdhImported
ORF Names:Dana_GF15589Imported, GF15589Imported
OrganismiDrosophila ananassae (Fruit fly)Imported
Taxonomic identifieri7217 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000007801 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0015055. Dana\Gpdh.

Subcellular locationi

Expressioni

Gene expression databases

BgeeiFBgn0015055.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7217.FBpp0118781.

Structurei

3D structure databases

ProteinModelPortaliB3MMP0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 174NAD_Gly3P_dh_NInterPro annotationAdd BLAST169
Domaini195 – 340NAD_Gly3P_dh_CInterPro annotationAdd BLAST146

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni270 – 271Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2711. Eukaryota.
COG0240. LUCA.
InParanoidiB3MMP0.
KOiK00006.
OMAiNMIGKGY.
OrthoDBiEOG091G0DO6.
PhylomeDBiB3MMP0.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
InterProiView protein in InterPro
IPR008927. 6-PGluconate_DH-like_C_sf.
IPR013328. 6PGD_dom2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR036291. NAD(P)-bd_dom_sf.
PfamiView protein in Pfam
PF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiView protein in PROSITE
PS00957. NAD_G3PDH. 1 hit.

Sequencei

Sequence statusi: Complete.

B3MMP0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEKVNVCIV GSGNWGSAIA KIVGANAAAL PEFEERVTMF VYEELIDGKK
60 70 80 90 100
LTEIINETHE NVKYLKGHKL PPNVVAVPDL VEAAKNADIL IFVVPHQFIP
110 120 130 140 150
NFCKQLLGKI KPNAIAISLI KGFDKAEGGG IDLISHIITR HLKIPCAVLM
160 170 180 190 200
GANLANEVAE GNFCETTIGC TDKKYGKVLR DLFQANHFRV VVVDDADAVE
210 220 230 240 250
VCGALKNIVA CGAGFVDGLK LGDNTKAAVI RLGLMEMIRF VDVFYPGSKL
260 270 280 290 300
STFFESCGVA DLITTCYGGR NRRVSEAFVT SGKTIEELEK EMLNGQKLQG
310 320 330 340 350
PPTAEEVNYM LKNKGLEDKF PLFTAIHKIC TNQLKPNDLI DCIRNHPEHM
360
DTSIMPSPKL
Length:360
Mass (Da):39,343
Last modified:September 2, 2008 - v1
Checksum:i634B35A506ADD99B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902620 Genomic DNA. Translation: EDV31931.1.
RefSeqiXP_001962710.1. XM_001962674.2.

Genome annotation databases

EnsemblMetazoaiFBtr0120289; FBpp0118781; FBgn0015055.
GeneIDi6507945.
KEGGidan:Dana_GF15589.

Similar proteinsi

Entry informationi

Entry nameiB3MMP0_DROAN
AccessioniPrimary (citable) accession number: B3MMP0
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: November 22, 2017
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported