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Protein

Angiotensin-converting enzyme

Gene

Dana\GF15534

Organism
Drosophila ananassae (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCarboxypeptidaseUniRule annotationImported, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Protein family/group databases

MEROPSiM02.002.

Names & Taxonomyi

Protein namesi
Recommended name:
Angiotensin-converting enzymeUniRule annotation (EC:3.4.-.-UniRule annotation)
Gene namesi
Name:Dana\GF15534Imported
ORF Names:Dana_GF15534Imported, GF15534Imported
OrganismiDrosophila ananassae (Fruit fly)Imported
Taxonomic identifieri7217 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000007801 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0092559. Dana\GF15534.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500279305024 – 631Angiotensin-converting enzymeSequence analysisAdd BLAST608

Keywords - PTMi

GlycoproteinUniRule annotation

Expressioni

Gene expression databases

BgeeiFBgn0092559.

Interactioni

Protein-protein interaction databases

STRINGi7217.FBpp0118726.

Structurei

3D structure databases

ProteinModelPortaliB3MLX8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3690. Eukaryota.
ENOG410XPJ3. LUCA.
InParanoidiB3MLX8.
KOiK01283.
OMAiSAWDFYQ.
OrthoDBiEOG091G033S.
PhylomeDBiB3MLX8.

Family and domain databases

CDDicd06461. M2_ACE. 1 hit.
InterProiView protein in InterPro
IPR001548. Peptidase_M2.
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiView protein in Pfam
PF01401. Peptidase_M2. 1 hit.
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Complete.

B3MLX8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLKSGMLAI GLVLLLWLPH GLSMGNSCSA SVLEARRFFE LENEQLRKRY
60 70 80 90 100
HEEFLSGYNY NTNVTEENRQ AMIEVYARNA ELNKRLAKTI KASDYAQSED
110 120 130 140 150
ASIRRQAEHL SKLGASALSA EDYLALQNAI SSMQSNYATV NVCSYTNRSD
160 170 180 190 200
CTLALEPEIQ ERLTHSRDPA ELAWYWREWY DKAGTPMREH FAEYVRLTRK
210 220 230 240 250
AAQLNGYPSY ADYWVQFYED TDFERQLDAA FKQLLPFYRQ IHGYVRYRLR
260 270 280 290 300
QHYGPEVVPA EGNIPMSLLG NMWGQSWNEV IDLFTPYPEK PFVDVKAEME
310 320 330 340 350
RQGYTVQKLF ELGDQFFQSL GMRALPSSFW NLSMLTRPTE RQVVCHASAW
360 370 380 390 400
DFYQDSDVRI KMCTEVDNHY FYVVHHELGH IQYYLQYEGQ PAVFRGAPNP
410 420 430 440 450
GFHEAVGDVI ALSVMSAKHL KTIGLIENGR LDEKSRINQL FKQALSKIVF
460 470 480 490 500
LPFGYAVEKY RYAVFRNELD ESQWNCGFWQ MRSEYGGLEP PVARTEKDFD
510 520 530 540 550
ATAKYHVDAD VEYLRYFAAH IFQFQFHKAL CRLAGQYAPD DSQLTLDNCD
560 570 580 590 600
IFGSKTAGRA LSQFLSKGSS RHWKEVLQEF TGETEMDPSA LLEYFDPLYQ
610 620 630
WLKKENSRLG VPLGWSQTNK IPSDCCGTFS T
Length:631
Mass (Da):73,034
Last modified:September 2, 2008 - v1
Checksum:i04C2CBA5E6493E19
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902620 Genomic DNA. Translation: EDV31806.1.
RefSeqiXP_001962585.1. XM_001962549.2.

Genome annotation databases

EnsemblMetazoaiFBtr0120234; FBpp0118726; FBgn0092559.
GeneIDi6498342.
KEGGidan:Dana_GF15534.

Similar proteinsi

Entry informationi

Entry nameiB3MLX8_DROAN
AccessioniPrimary (citable) accession number: B3MLX8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: August 30, 2017
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported