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Protein

Protein clueless

Gene

clu

Organism
Drosophila ananassae (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.UniRule annotation

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Protein cluelessUniRule annotation
Alternative name(s):
Clustered mitochondria protein homologUniRule annotation
Gene namesi
Name:cluUniRule annotation
ORF Names:GF12179
OrganismiDrosophila ananassae (Fruit fly)
Taxonomic identifieri7217 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000007801 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0089218. Dana\GF12179.

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 14501450Protein cluelessPRO_0000366379Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei271 – 2711PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi7217.FBpp0115371.

Structurei

3D structure databases

ProteinModelPortaliB3MIW0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati1102 – 113534TPR 1Add
BLAST
Repeati1228 – 126134TPR 2Add
BLAST
Repeati1263 – 129634TPR 3Add
BLAST

Sequence similaritiesi

Belongs to the CLU family.UniRule annotation
Contains 3 TPR repeats.UniRule annotation

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

eggNOGiKOG1839. Eukaryota.
ENOG410XQUQ. LUCA.
InParanoidiB3MIW0.
KOiK03255.
OMAiMYLYVIT.
OrthoDBiEOG72RMX5.
PhylomeDBiB3MIW0.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
HAMAPiMF_03013. CLU.
InterProiIPR027523. CLU.
IPR025697. CLU_dom.
IPR028275. CLU_N.
IPR007967. DUF727.
IPR023231. GSKIP_dom.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF13236. CLU. 1 hit.
PF15044. CLU_N. 1 hit.
PF05303. DUF727. 1 hit.
PF13374. TPR_10. 1 hit.
[Graphical view]
SUPFAMiSSF103107. SSF103107. 1 hit.
SSF48452. SSF48452. 2 hits.

Sequencei

Sequence statusi: Complete.

B3MIW0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALETDAKNS NAVAPGDAAT VATTKAKENN SSAGKKQQQQ QQPNQNQNLV
60 70 80 90 100
NGNGNAADGP AAKKKGKKNR NKSPPEPAAE PVEASLSNGH AEKTTSEEGG
110 120 130 140 150
DTAAPDTNAN VGEKSEDGGG AAPGSELETE DIDLDALHEV GITVNISSPG
160 170 180 190 200
ADILSVQLSS MELVQEIHQL LMDREETCHR TCFSLQLDNV TLDNFAELKT
210 220 230 240 250
IEQLEQGSTI RVVEEPYTMR EARIHVRHVR DLLKNLDPAD AYNGIDCTSL
260 270 280 290 300
TYLNTITQGD LLDKKKTRPD SVDCTPPEYV TPGVSEPPLL PLHPNIKNAK
310 320 330 340 350
GPQALKVLTT SAWNPPPGPR KLHGDLMYLY VVTMEDKRFH ISACSKGFYI
360 370 380 390 400
NQSTDDTFNP KPDNPSHLSH SLIDLLSHIS PSFRRAFQTI QKRRTTRHAF
410 420 430 440 450
ERVATPYQVY QWASPVLEHT VDAIRAEDAF SSKLGYEEHI PGQTRDWNEE
460 470 480 490 500
LQTTRELPRK TLPERLLRER AIFKVHGDFV TAATRGAMAV IDGNVLAINP
510 520 530 540 550
GEDAKMQMFI WNNIFFSLGF DVRDHYKELG GDAAAFVAPR YDLHGVRVYN
560 570 580 590 600
AVDVEGLYTL GTVVIDYRGY RVTAQSIIPG ILEREQEQSV VYGSIDFGKT
610 620 630 640 650
VLSHPKYLDL LRQAGKHLKI LPHAVLNERD EPVELCSSVE CKGIIGNDGR
660 670 680 690 700
HYILDLLRTF PPDVNFLKLP EVQLSKELVD MGFPIEHRHK LCCLRQELLE
710 720 730 740 750
AFIEDRYVSF IRIAAVHLQQ LNAKKQSEKT EEKALPALEE AEKESSETKE
760 770 780 790 800
AEAEKPVEKK EEEKQQPSSN ETKTAEAMVN AIREAQSNVA TSNEVQAAEV
810 820 830 840 850
VKRACAAVGS LKEKEFDFRF NPDVFSNGIR HVDGEEGTCS SLAKQKVLVQ
860 870 880 890 900
DAAEFLVVKQ IPAFIKEHLA HSSPPIDGQS LTESLHSHGI NVRYLGKVIK
910 920 930 940 950
LLAQMPRMDY LHRIAVLELI VRATKHIYYT YMQNTEPLHL SAAISHFLNC
960 970 980 990 1000
LLTTGPVNPA VSSEEAHKKR SNGNKHNKHK SKGNKQQASG NQNGSSAGSS
1010 1020 1030 1040 1050
SGGSSSSSDW TLVTPRSLWQ QIRREAKSYW DWELDCDSIE TAVSKYGILR
1060 1070 1080 1090 1100
ISLLRAFCLK VGIQVLLREY NFESKHKPTF GDEDIVNVFP VVKHISPRAT
1110 1120 1130 1140 1150
DAYNFYTTGQ AKIQQGMFKE GYELISEALN LLNNVFGAMH QENGSCLRML
1160 1170 1180 1190 1200
ARLSYLLGDA QDALAIQQRA VIMSERVNGI DHPSTILEYT HLSLYSFANG
1210 1220 1230 1240 1250
HVGMSLKLLY RARYLMVLIC GEDHPEVALI DSNISLILHA LGEYELSLRF
1260 1270 1280 1290 1300
IEHALKLNIK YFGSKAMHVA FSYHLMARTQ SCMGDFRSAL NNEKETYSIY
1310 1320 1330 1340 1350
KSQVGEKHEK TRDSAECLRL LTQQAVLLQR KMNDIYSNGK LTSDLPPIHI
1360 1370 1380 1390 1400
TPPSMGSVLD MLNTINGILF VQISQKDIVK VRSEIEKHFK ANSAENEVND
1410 1420 1430 1440 1450
AIKSIVAAAN NNGDTEAETK DATKDNKDLA GASTQLTNGD KDAETAVASS
Length:1,450
Mass (Da):161,078
Last modified:September 2, 2008 - v1
Checksum:i9EF4AD43F89067C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902619 Genomic DNA. Translation: EDV36020.1.
RefSeqiXP_001959198.1. XM_001959162.2.

Genome annotation databases

EnsemblMetazoaiFBtr0116879; FBpp0115371; FBgn0089218.
GeneIDi6495035.
KEGGidan:Dana_GF12179.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902619 Genomic DNA. Translation: EDV36020.1.
RefSeqiXP_001959198.1. XM_001959162.2.

3D structure databases

ProteinModelPortaliB3MIW0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7217.FBpp0115371.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0116879; FBpp0115371; FBgn0089218.
GeneIDi6495035.
KEGGidan:Dana_GF12179.

Organism-specific databases

FlyBaseiFBgn0089218. Dana\GF12179.

Phylogenomic databases

eggNOGiKOG1839. Eukaryota.
ENOG410XQUQ. LUCA.
InParanoidiB3MIW0.
KOiK03255.
OMAiMYLYVIT.
OrthoDBiEOG72RMX5.
PhylomeDBiB3MIW0.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
HAMAPiMF_03013. CLU.
InterProiIPR027523. CLU.
IPR025697. CLU_dom.
IPR028275. CLU_N.
IPR007967. DUF727.
IPR023231. GSKIP_dom.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF13236. CLU. 1 hit.
PF15044. CLU_N. 1 hit.
PF05303. DUF727. 1 hit.
PF13374. TPR_10. 1 hit.
[Graphical view]
SUPFAMiSSF103107. SSF103107. 1 hit.
SSF48452. SSF48452. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 14024-0371.13.

Entry informationi

Entry nameiCLU_DROAN
AccessioniPrimary (citable) accession number: B3MIW0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 2, 2008
Last modified: March 16, 2016
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.