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Protein

Hexokinase

Gene

Dana\GF12622

Organism
Drosophila ananassae (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. kinase activity Source: UniProtKB-KW
  3. phosphotransferase activity, alcohol group as acceptor Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
Name:Dana\GF12622Imported
ORF Names:Dana_GF12622Imported, GF12622Imported
OrganismiDrosophila ananassae (Fruit fly)Imported
Taxonomic identifieri7217 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000007801 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0089658. Dana\GF12622.

Interactioni

Protein-protein interaction databases

STRINGi7217.FBpp0115814.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation
Contains 1 hexokinase type-1 domain.UniRule annotation
Contains 1 hexokinase type-2 domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG5026.
InParanoidiB3MGJ9.
KOiK00844.
OrthoDBiEOG7S21X5.
PhylomeDBiB3MGJ9.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.

Sequencei

Sequence statusi: Complete.

B3MGJ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDAEVRELM QAFVLSDYQV QEVYSRFCLE VARGLKRSTH PQANVKCFPT
60 70 80 90 100
YVQDLPTGDE MGKYLALDLG GTNFRVLLVS LKGHHDASVE SQIYAVPKDL
110 120 130 140 150
MVGSGVDLFD HIADCLAKFV EKHNMKTAYL PLGFTFSFPC VQVGLKEGLL
160 170 180 190 200
VRWTKGFDCA GCEGEDVGRM LHEAIQRRGD ADIAVVAILN DTTGTLMSCA
210 220 230 240 250
HRNPDCRVGV IVGTGCNACY VEEVENVDLL HPDFKRTKKQ VIINAEWGAF
260 270 280 290 300
GEGGQLDFVR TEYDREVDEK SINRSQQLFE KMTAGMYLGN LVRLVLLRAL
310 320 330 340 350
ERKLIFRQSS RRPEFATVLQ KHQDVFETRY ISEIEDDTFP EFASTRSIVK
360 370 380 390 400
KLFGIEKASV EDCQTLKYIC ECVAKRAATL VAIGVSGLIN RTSNKSVVVG
410 420 430 440 450
MDGSVYRYHP KFDAYMREVL VKLVKSDKAW DIMLSEDGSG RGAALVAAVA

SKTK
Length:454
Mass (Da):50,662
Last modified:September 1, 2008 - v1
Checksum:iCD320F81A11F7AA2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902619 Genomic DNA. Translation: EDV35742.1.
RefSeqiXP_001958920.1. XM_001958884.1.

Genome annotation databases

EnsemblMetazoaiFBtr0117322; FBpp0115814; FBgn0089658.
GeneIDi6495471.
KEGGidan:Dana_GF12622.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902619 Genomic DNA. Translation: EDV35742.1.
RefSeqiXP_001958920.1. XM_001958884.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7217.FBpp0115814.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0117322; FBpp0115814; FBgn0089658.
GeneIDi6495471.
KEGGidan:Dana_GF12622.

Organism-specific databases

FlyBaseiFBgn0089658. Dana\GF12622.

Phylogenomic databases

eggNOGiCOG5026.
InParanoidiB3MGJ9.
KOiK00844.
OrthoDBiEOG7S21X5.
PhylomeDBiB3MGJ9.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 14024-0371.13Imported.

Entry informationi

Entry nameiB3MGJ9_DROAN
AccessioniPrimary (citable) accession number: B3MGJ9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2008
Last sequence update: September 1, 2008
Last modified: March 3, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.