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B3LLX6

- YM084_YEAS1

UniProt

B3LLX6 - YM084_YEAS1

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Protein
Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing]
Gene
SCRG_01975
Organism
Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins) By similarity.

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei2 – 21Nucleophile; for GATase activity By similarity

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. UDP-N-acetylglucosamine biosynthetic process Source: UniProtKB-UniPathway
  2. carbohydrate metabolic process Source: InterPro
  3. glutamine metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Enzyme and pathway databases

UniPathwayiUPA00113; UER00528.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing] (EC:2.6.1.16)
Short name:
GFAT
Alternative name(s):
D-fructose-6-phosphate amidotransferase
Hexosephosphate aminotransferase
Gene namesi
ORF Names:SCRG_01975
OrganismiSaccharomyces cerevisiae (strain RM11-1a) (Baker's yeast)
Taxonomic identifieri285006 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000008335: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 720720Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing]
PRO_0000377747Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliB3LLX6.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 321320Glutamine amidotransferase type-2
Add
BLAST
Domaini393 – 532140SIS 1
Add
BLAST
Domaini565 – 710146SIS 2
Add
BLAST

Sequence similaritiesi

Contains 2 SIS domains.

Keywords - Domaini

Glutamine amidotransferase, Repeat

Phylogenomic databases

OrthoDBiEOG7034RG.

Family and domain databases

Gene3Di3.60.20.10. 2 hits.
InterProiIPR017932. GATase_2_dom.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view]
PfamiPF01380. SIS. 2 hits.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 2 hits.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3LLX6-1 [UniParc]FASTAAdd to Basket

« Hide

MCGIFGYCNF LIEKTRGEII DTLIEGLQAL EYKEYDSSGI SIQGDELKSL    50
NIYKQTGKIS SLKEEIDLYN LNKNLPFISH CGIAHTRRAT HGGLRRANCH 100
PHNSDPSNEF VVVHNGVITN FANLKALLVA KGYVFKSDTD TECIPKLYKH 150
IYDTSIELGY NLDFHVLTNL VLKELEGSYG LLCTSSHFPD EVVAARKGSP 200
LVIGVKGKTD MDVNFVEVEY LDQEEDYLKL NTQTKSSGNV LAAAPVKYNT 250
CLRKSPPLRS QYLRNSTTST FNHGSSTETP AENGLPRPME FYLSSDCASL 300
ARYVSKVVYL EDNDIAHIYD GELHIHCSKI GSEDFSFRTV QKLELELSKI 350
KKGPYDNFMQ KEIYEQCETT KNVMRGRVDA FTNRVVLGGL ENWLTELRRA 400
KRIIMIASKS SFHSCLAARP IFEELMEVPV NVELALDFVD RNCCIFRNDV 450
CIFVSRSGET TDTINALNYC IKKEAVTIGV VNCSGSSISR FTHCGVHTNT 500
GPEKGIATTK SYTSQYIALV MIALWMSEDL VSKIERRKEI IQALTIIPSQ 550
IKEVLELEPL IIELCDKKLK QHDTFLLLGR GYQFASALEG ASKMKEISYV 600
HSESILTDEL GHRVLAVASD NPPIIAFATK DAFSPKIASC IDQIIERKGN 650
PIIICNKGHK IWEQDKQKGN VVTLEVPQTV DCLQGILNVI PLQLISYWLA 700
IKKDIGVDLP RDSAMSAPDI 720
Length:720
Mass (Da):80,557
Last modified:September 2, 2008 - v1
Checksum:iD68AA1B784162DD9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH408047 Genomic DNA. Translation: EDV11579.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH408047 Genomic DNA. Translation: EDV11579.1 .

3D structure databases

ProteinModelPortali B3LLX6.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

OrthoDBi EOG7034RG.

Enzyme and pathway databases

UniPathwayi UPA00113 ; UER00528 .

Family and domain databases

Gene3Di 3.60.20.10. 2 hits.
InterProi IPR017932. GATase_2_dom.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view ]
Pfami PF01380. SIS. 2 hits.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 2 hits.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RM11-1a.

Entry informationi

Entry nameiYM084_YEAS1
AccessioniPrimary (citable) accession number: B3LLX6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: September 2, 2008
Last modified: June 11, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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