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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

PKH_143330

Organism
Plasmodium knowlesi (strain H)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei134SubstrateUniRule annotation1
Active sitei218Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

NADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
ORF Names:PKH_143330Imported, PKNA1_C2_1435700Imported, PKNA1_H1_1435700Imported
OrganismiPlasmodium knowlesi (strain H)Imported
Taxonomic identifieri5851 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Plasmodium)
Proteomesi
  • UP000031513 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiPlasmoDB:PKNH_1435700.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 186NAD_Gly3P_dh_NInterPro annotationAdd BLAST172
Domaini208 – 354NAD_Gly3P_dh_CInterPro annotationAdd BLAST147

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni282 – 283Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000246855.
InParanoidiB3LCF6.
KOiK00006.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.

Sequencei

Sequence statusi: Complete.

B3LCF6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYKSLFDKLK EGPLKISILG SGNWASAISK VVGTNAKNNY LFENEVKMWV
60 70 80 90 100
RDERVNGESI VDIINKKHEN VKYLKGVSLP HNIVAYSDLS KVINSADLLI
110 120 130 140 150
FIIPSQYLEN ALKLIKENQS INIGKHTRAI SLTKGFIIKN NEMYLCSKYI
160 170 180 190 200
SNLLGIPCSA LSGANIAMDV AMEEFSEATI GGNENETLLI WQRVFDLPYF
210 220 230 240 250
KINCVNETVG VEIFGALKNI ITLAAGFCDG LNASTNSKSA IIRIGVKESF
260 270 280 290 300
LFGKTFFNYS DVSIFFESCG LADIITSFLS GRNAKCSAEF VKCKPKKTWE
310 320 330 340 350
QLESEILKGQ KLQGIVTLKY VYQMIKKNDL THEFPLFTIL HKISFENGDP
360
RELLNIFMNN TVSGIAT
Length:367
Mass (Da):40,994
Last modified:September 2, 2008 - v1
Checksum:i3DB2EE664BD7BC86
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM910996 Genomic DNA. Translation: CAQ42115.1.
CWHQ01000003 Genomic DNA. Translation: CRX56912.1.
CWHR01000002 Genomic DNA. Translation: CRX59615.1.
CWHQ02000003 Genomic DNA. Translation: SBO20822.1.
CWHR02000002 Genomic DNA. Translation: SBO21245.1.
RefSeqiXP_002262237.1. XM_002262201.1.

Genome annotation databases

EnsemblProtistsiCAQ42115; CAQ42115; PKH_143330.
PKH_143330; PKH_143330; PKH_143330.
GeneIDi7323256.
KEGGipkn:PKH_143330.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM910996 Genomic DNA. Translation: CAQ42115.1.
CWHQ01000003 Genomic DNA. Translation: CRX56912.1.
CWHR01000002 Genomic DNA. Translation: CRX59615.1.
CWHQ02000003 Genomic DNA. Translation: SBO20822.1.
CWHR02000002 Genomic DNA. Translation: SBO21245.1.
RefSeqiXP_002262237.1. XM_002262201.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiCAQ42115; CAQ42115; PKH_143330.
PKH_143330; PKH_143330; PKH_143330.
GeneIDi7323256.
KEGGipkn:PKH_143330.

Organism-specific databases

EuPathDBiPlasmoDB:PKNH_1435700.

Phylogenomic databases

HOGENOMiHOG000246855.
InParanoidiB3LCF6.
KOiK00006.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB3LCF6_PLAKH
AccessioniPrimary (citable) accession number: B3LCF6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: November 2, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.