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Protein

Hexokinase

Gene

PKH_112550

Organism
Plasmodium knowlesi (strain H)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
ORF Names:PKH_112550Imported
OrganismiPlasmodium knowlesi (strain H)Imported
Taxonomic identifieri5851 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiumPlasmodium (Plasmodium)
ProteomesiUP000031513 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiPlasmoDB:PKH_112550.

Interactioni

Protein-protein interaction databases

STRINGi5850.PKH_112550.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation
Contains 1 hexokinase type-1 domain.UniRule annotation
Contains 1 hexokinase type-2 domain.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000162670.
InParanoidiB3L7G9.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3L7G9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYYNLEKDD TVYYKLDTIK CDIPINEELQ ARINKHVNQL RITYSTLEEF
60 70 80 90 100
VDNFVYELKK GLEAHRRHPN LWIPHECSFK MLDSCIADIP TGQEKGTYYA
110 120 130 140 150
IDFGGTNFRA VRASLDGNGK IKRDQETYSL KFTGTFSHEK GLLDKHATAS
160 170 180 190 200
QLFDHFAERI KYIMGEFKDL DNREGKNVGF TFSFPCTSPS INCSILIDWT
210 220 230 240 250
KGFETGRATN DPVEGRDVCK LMNDAFVRSE VPAKVCCVVN DAVGTLMSCA
260 270 280 290 300
YQKGKTTPPC YIGIILGTGS NGCYYEPEWK KYKYAGKIIN IELGNFDKDL
310 320 330 340 350
PLTPIDLVMD WYSANRSRQL FEKMISGAYL GEIVRRFMVN VLQSASSEKM
360 370 380 390 400
WKSDSFNSES GSVVLNDTSP NFEDSRKVAK AAWDMDFTDE QIYALRKICE
410 420 430 440 450
SVYNRSAALA AAAIAAIAKR IKIIEHSKFS CGVDGSLFVK NAWYCKRLQE
460 470 480 490
HLKVILADKA ENLIIIPADD GSGKGAAITA AVVSQSSSIK RLP
Length:493
Mass (Da):55,402
Last modified:September 2, 2008 - v1
Checksum:i09E164093B85B3BA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM910993 Genomic DNA. Translation: CAQ40842.1.
RefSeqiXP_002261437.1. XM_002261401.1.

Genome annotation databases

EnsemblProtistsiPKH_112550; PKH_112550; PKH_112550.
GeneIDi7321553.
KEGGipkn:PKH_112550.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM910993 Genomic DNA. Translation: CAQ40842.1.
RefSeqiXP_002261437.1. XM_002261401.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5850.PKH_112550.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiPKH_112550; PKH_112550; PKH_112550.
GeneIDi7321553.
KEGGipkn:PKH_112550.

Organism-specific databases

EuPathDBiPlasmoDB:PKH_112550.

Phylogenomic databases

HOGENOMiHOG000162670.
InParanoidiB3L7G9.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HImported.

Entry informationi

Entry nameiB3L7G9_PLAKH
AccessioniPrimary (citable) accession number: B3L7G9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: April 1, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.