B3L0V6 (B3L0V6_PLAKH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aspartate aminotransferase RuleBase RU000480
EC=2.6.1.1 RuleBase RU000480

Gene names

ORF Names:

PKH_041530 EMBL CAQ38525.1

Organism

Plasmodium knowlesi (strain H) [Reference proteome]

Taxonomic identifier

5851 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodium › Plasmodium (Plasmodium) › Plasmodium knowlesi

Protein attributes

Sequence length	417 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate. RuleBase RU000480
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000479
Subunit structure	Homodimer By similarity. RuleBase RU000480
Miscellaneous	In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes By similarity. RuleBase RU000480
Sequence similarities	Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. RuleBase RU000479

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000479
Molecular function	Aminotransferase RuleBase RU000480 EMBL CAQ38525.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	biosynthetic process Inferred from electronic annotation. Source: InterPro cellular amino acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	L-aspartate:2-oxoglutarate aminotransferase activity Inferred from electronic annotation. Source: EC L-phenylalanine:2-oxoglutarate aminotransferase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B3L0V6 [UniParc]. Last modified September 2, 2008. Version 1. Checksum: E8242CF4FE802B98	FASTA	417	48,089
	10 20 30 40 50 60 MDALIGQLED VEPDSILKSA EDFKNDKSDV KVNLSIGVCC NENGELHIFK SVLDAEKLVQ 70 80 90 100 110 120 QRYKEKPYLL SNGTEQFSIL TQELIFGDNS KYIKEKRICT IQAIGGTGAI FIALQFFKML 130 140 150 160 170 180 HIQEICVTNS PYINHVNMIK SYGFNVKYIS FFEEKLVNIN YDAFLYDLRN LEDGSVVILQ 190 200 210 220 230 240 VSCYNPCSTN IEEIYFDEIA DIVWKKKHVI LFDVAYQGFG SSNLNDDVSL IRKFEERGLS 250 260 270 280 290 300 FVVCQSFSKN MSLYGERAGA LHIICKSKEE RKIVANNLRM ITRKFYSSPT IHTNRIVCEL 310 320 330 340 350 360 LENEKLKSEW ISDLRKLSER VHKNRVLFFD KMEFYQKKFD LHYDWSVYKK QRGIFSFVPP 370 380 390 400 410 FAGIYDMLKE HHVYIIDSGR INVSGITTRN VDYVAEKACL CLAVKQKGKA GNQGENP

References

[1]

"The genome of the simian and human malaria parasite Plasmodium knowlesi." Pain A., Boehme U., Berry A.E., Mungall K., Finn R.D., Jackson A.P., Mourier T., Mistry J., Pasini E.M., Aslett M.A., Balasubrammaniam S., Borgwardt K., Brooks K., Carret C., Carver T.J., Cherevach I., Chillingworth T., Clark T.G. , Galinski M.R., Hall N., Harper D., Harris D., Hauser H., Ivens A., Janssen C.S., Keane T., Larke N., Lapp S., Marti M., Moule S., Meyer I.M., Ormond D., Peters N., Sanders M., Sanders S., Sargeant T.J., Simmonds M., Smith F., Squares R., Thurston S., Tivey A.R., Walker D., White B., Zuiderwijk E., Churcher C., Quail M.A., Cowman A.F., Turner C.M.R., Rajandream M.A., Kocken C.H.M., Thomas A.W., Newbold C.I., Barrell B.G., Berriman M. Nature 455:799-803(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: H.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM910986 Genomic DNA. Translation: CAQ38525.1.
RefSeq	XP_002257988.1. XM_002257952.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	5850.PKH_041530.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	PKH_041530; PKH_041530; PKH_041530.
GeneID	7319294.
KEGG	pkn:PKH_041530.
Organism-specific databases
EuPathDB	PlasmoDB:PKH_041530.
Phylogenomic databases
HOGENOM	HOG000284241.
KO	K00813.
ProtClustDB	PTZ00376.
Family and domain databases
Gene3D	3.40.640.10. 1 hit. 3.90.1150.10. 1 hit.
InterPro	IPR004839. Aminotransferase_I/II. IPR000796. Asp_trans. IPR004838. NHTrfase_class1_PyrdxlP-BS. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
PANTHER	PTHR11879. PTHR11879. 1 hit.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
PRINTS	PR00799. TRANSAMINASE.
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITE	PS00105. AA_TRANSFER_CLASS_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B3L0V6_PLAKH

Accession

Primary (citable) accession number: B3L0V6

Entry history

Integrated into UniProtKB/TrEMBL:	September 2, 2008
Last sequence update:	September 2, 2008
Last modified:	April 3, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)