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Protein

Aspartate aminotransferase

Gene

PKH_041530

Organism
Plasmodium knowlesi (strain H)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. L-aspartate:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
  2. L-phenylalanine:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
  3. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. biosynthetic process Source: InterPro
  2. cellular amino acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseUniRule annotationImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate aminotransferaseUniRule annotation (EC:2.6.1.1UniRule annotation)
Gene namesi
ORF Names:PKH_041530Imported
OrganismiPlasmodium knowlesi (strain H)Imported
Taxonomic identifieri5851 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiumPlasmodium (Plasmodium)
ProteomesiUP000000622: Chromosome 4

Organism-specific databases

EuPathDBiPlasmoDB:PKH_041530.

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi5850.PKH_041530.

Family & Domainsi

Sequence similaritiesi

Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000284241.
InParanoidiB3L0V6.
KOiK14455.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR000796. Asp_trans.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11879. PTHR11879. 1 hit.
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSiPR00799. TRANSAMINASE.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3L0V6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDALIGQLED VEPDSILKSA EDFKNDKSDV KVNLSIGVCC NENGELHIFK
60 70 80 90 100
SVLDAEKLVQ QRYKEKPYLL SNGTEQFSIL TQELIFGDNS KYIKEKRICT
110 120 130 140 150
IQAIGGTGAI FIALQFFKML HIQEICVTNS PYINHVNMIK SYGFNVKYIS
160 170 180 190 200
FFEEKLVNIN YDAFLYDLRN LEDGSVVILQ VSCYNPCSTN IEEIYFDEIA
210 220 230 240 250
DIVWKKKHVI LFDVAYQGFG SSNLNDDVSL IRKFEERGLS FVVCQSFSKN
260 270 280 290 300
MSLYGERAGA LHIICKSKEE RKIVANNLRM ITRKFYSSPT IHTNRIVCEL
310 320 330 340 350
LENEKLKSEW ISDLRKLSER VHKNRVLFFD KMEFYQKKFD LHYDWSVYKK
360 370 380 390 400
QRGIFSFVPP FAGIYDMLKE HHVYIIDSGR INVSGITTRN VDYVAEKACL
410
CLAVKQKGKA GNQGENP
Length:417
Mass (Da):48,089
Last modified:September 2, 2008 - v1
Checksum:iE8242CF4FE802B98
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM910986 Genomic DNA. Translation: CAQ38525.1.
RefSeqiXP_002257988.1. XM_002257952.1.

Genome annotation databases

EnsemblProtistsiPKH_041530; PKH_041530; PKH_041530.
GeneIDi7319294.
KEGGipkn:PKH_041530.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM910986 Genomic DNA. Translation: CAQ38525.1.
RefSeqiXP_002257988.1. XM_002257952.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5850.PKH_041530.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiPKH_041530; PKH_041530; PKH_041530.
GeneIDi7319294.
KEGGipkn:PKH_041530.

Organism-specific databases

EuPathDBiPlasmoDB:PKH_041530.

Phylogenomic databases

HOGENOMiHOG000284241.
InParanoidiB3L0V6.
KOiK14455.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR000796. Asp_trans.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11879. PTHR11879. 1 hit.
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSiPR00799. TRANSAMINASE.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HImported.

Entry informationi

Entry nameiB3L0V6_PLAKH
AccessioniPrimary (citable) accession number: B3L0V6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: February 4, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.