B3KYA7 (B3KYA7_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Serine/threonine-protein kinase 3 36kDa subunit Ensembl ENSP00000429744

Submitted name:
cDNA FLJ16404 fis, clone UTERU2008019, highly similar to Serine/threonine-protein kinase 3 (EC 2.7.11.1) EMBL BAG54769.1

Gene names

Name:

STK3 Ensembl ENSP00000429744

Organism

Homo sapiens (Human) [Reference proteome] EMBL BAG54769.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	519 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304 Nucleotide-binding
Molecular function	Kinase EMBL BAG54769.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	signal transduction Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B3KYA7 [UniParc]. Last modified September 2, 2008. Version 1. Checksum: 84CB5FEAA629AE68	FASTA	519	59,462
	10 20 30 40 50 60 MLQLMDSGIT ICLRNGAASV FKKKEWSTQG EENKQDSKLK KLSEDSLTKQ PEEVFDVLEK 70 80 90 100 110 120 LGEGSYGSVF KAIHKESGQV VAIKQVPVES DLQEIIKEIS IMQQCDSPYV VKYYGSYFKN 130 140 150 160 170 180 TDLWIVMEYC GAGSVSDIIR LRNKTLIEDE IATILKSTLK GLEYLHFMRK IHRDIKAGNI 190 200 210 220 230 240 LLNTEGHAKL ADFGVAGQLT DTMAKRNTVI GTPFWMAPEV IQEIGYNCVA DIWSLGITSI 250 260 270 280 290 300 EMAEGKPPYA DIHPMRAIFM IPTNPPPTFR KPELWSDDFT DFVKKCLVKN PEQRATATQL 310 320 330 340 350 360 LQHPFIKNAK PVSILRDLIT EAMEIKAKRH EEQQRELEEE EENSDEDELD SHTMVKTSVE 370 380 390 400 410 420 SVGTMRATST MSEGAQTMIE HNSTMLESDL GTMVINSEDE EEEDGTMKRN ATSPQVQRPS 430 440 450 460 470 480 FMDYFDKQDF KNKSHENCNQ NMHEPFPMSK NVFPDNWKVP QDGDFDFLKN LSLEELQMRL 490 500 510 KALDPMMERE IEELRQRYTA KRQPILDAMD AKKRRQQNF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"NEDO human cDNA sequencing project." Oshima A., Takahashi-Fujii A., Tanase T., Imose N., Takeuchi K., Arita M., Musashino K., Yuuki H., Hara H., Sugiyama T., Irie R., Otsuki T., Sato H., Wakamatsu A., Ishii S., Yamamoto J., Isono Y., Kawai-Hio Y. , Saito K., Nishikawa T., Kimura K., Yamashita H., Matsuo K., Nakamura Y., Sekine M., Kikuchi H., Kanda K., Wagatsuma M., Murakawa K., Kanehori K., Sugiyama A., Kawakami B., Suzuki Y., Sugano S., Nagahari K., Masuho Y., Nagai K., Isogai T. Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Uterus EMBL BAG54769.1.
[2]	"DNA sequence and analysis of human chromosome 8." Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S., Asakawa T. , Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Glockner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P., Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H., Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B., O'Neill K., Parker S.C., Polley A., Raymond C.K., Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N., Lander E.S. Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC016877 Genomic DNA. No translation available. AP002087 Genomic DNA. No translation available. AP003355 Genomic DNA. No translation available. AP003467 Genomic DNA. No translation available. AP003551 Genomic DNA. No translation available. AK131363 mRNA. Translation: BAG54769.1.
IPI	IPI00411984.
RefSeq	NP_001243241.1. NM_001256312.1.
UniGene	Hs.492333.
3D structure databases
SMR	B3KYA7. Positions 54-323, 464-512.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000390500.
Proteomic databases
PRIDE	B3KYA7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000523601; ENSP00000429744; ENSG00000104375.
GeneID	6788.
KEGG	hsa:6788.
UCSC	uc003yio.3. human.
Organism-specific databases
CTD	6788.
HGNC	HGNC:11406. STK3.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000234203.
HOVERGEN	HBG108518.
KO	K04412.
OMA	MVKTSVE.
OrthoDB	EOG4N30P2.
Gene expression databases
ArrayExpress	B3KYA7.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR024205. Mst1_SARAH_domain. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR011524. SARAH_dom. IPR002290. Ser/Thr_dual-sp_kinase_dom. [Graphical view]
Pfam	PF11629. Mst1_SARAH. 1 hit. PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS50951. SARAH. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	STK3. human.
GenomeRNAi	6788.
NextBio	26504.

Entry information

Entry name

B3KYA7_HUMAN

Accession

Primary (citable) accession number: B3KYA7

Entry history

Integrated into UniProtKB/TrEMBL:	September 2, 2008
Last sequence update:	September 2, 2008
Last modified:	May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.