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Protein
Submitted name:

cDNA FLJ46571 fis, clone THYMU3041428, highly similar to Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHelicaseUniRule annotationImported, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ46571 fis, clone THYMU3041428, highly similar to Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134934941.

PTM / Processingi

Proteomic databases

MaxQBiB3KY11.
PaxDbiB3KY11.
PeptideAtlasiB3KY11.
PRIDEiB3KY11.

Expressioni

Gene expression databases

GenevisibleiB3KY11. HS.

Structurei

3D structure databases

ProteinModelPortaliB3KY11.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini371 – 399Q_MOTIFInterPro annotationAdd BLAST29
Domaini402 – 607Helicase ATP-bindingInterPro annotationAdd BLAST206
Domaini631 – 779Helicase C-terminalInterPro annotationAdd BLAST149

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili144 – 181Sequence analysisAdd BLAST38
Coiled coili303 – 330Sequence analysisAdd BLAST28

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi371 – 399Q motifPROSITE-ProRule annotationAdd BLAST29

Sequence similaritiesi

Belongs to the DEAD box helicase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0333. Eukaryota.
ENOG410XNVG. LUCA.
HOGENOMiHOG000268796.
HOVERGENiHBG102054.
KOiK12858.

Family and domain databases

InterProiView protein in InterPro
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR014014. RNA_helicase_DEAD_Q_motif.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiView protein in PROSITE
PS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.

Sequencei

Sequence statusi: Complete.

B3KY11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGELADKKD RDASPSKEER KRSRTPDRER DRDRDRKSSP SKDRKRHRSR
60 70 80 90 100
DRRRGGSRSR SRSRSKSAER ERRHKERERD KERDRNKKDR DRGKDFKSRK
110 120 130 140 150
DRDSKKDEED EHGDKKPKAQ PLSLEELLAK KKAEEEAEAK PKFLSKAERE
160 170 180 190 200
AEALKRRQQE VEERQRMLEE ERKKRKQFQD LGRKMLEDPQ ERERRERRER
210 220 230 240 250
MERETNGNED EEGRQKIREE KDKSKELHAI KERYLGGIKK RRRTRHLNDR
260 270 280 290 300
KFVFEWDASE DTSIDYNPLY KERHQVQLLG RGFIAGIDLK QQKREQSRFY
310 320 330 340 350
GDLMEKRRTL EEKEQEEARL RKLRKKEAKQ RWDDRHWSQK KLDEMTDRDW
360 370 380 390 400
RIFREDYSIT TKGGKIPNPI RSWKDSSLPP HILEVIDKCG YKEPTPIQRQ
410 420 430 440 450
AIPIGLQNRD IIGVAETGSG KTAAFLIPLL VWITTLPKID RIEESDQGPY
460 470 480 490 500
AIILAPTREL AQQIEEETIK FGKPLGIRTV AVIGGISRED QGFRLRMGCE
510 520 530 540 550
IVIATPGRLI DVLENRYLVL SRCTYVVLDE ADRMIDMGFE PDVQKILEHM
560 570 580 590 600
PVSNQKPDTD EAEDPEKMLA NFESGKHKYR QTVMFTATMP PAVERLARSY
610 620 630 640 650
LRRPAVVYIG SAGKPHERVE QKVFLMSESE KRKKLLAILE QGFDPPIIIF
660 670 680 690 700
VNQKKGCDVL AKSLEKMGYN ACTLHGGKGQ EQREFALSNL KAGAKDILVA
710 720 730 740 750
TDVAGRGIDI QDVSMVVNYD MAKNIEDYIH RIGRTGRAGK SGVAITFLTK
760 770 780 790 800
EDSAVFYELK QAILESPVSS CPPELANHPD AQHKPGTILT KKRREETIFA
Length:800
Mass (Da):93,234
Last modified:September 2, 2008 - v1
Checksum:iC071691EAB2A03D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK128428 mRNA. Translation: BAG54673.1.
RefSeqiNP_004809.2. NM_004818.2.
UniGeneiHs.130098.

Genome annotation databases

GeneIDi9416.
KEGGihsa:9416.

Similar proteinsi

Entry informationi

Entry nameiB3KY11_HUMAN
AccessioniPrimary (citable) accession number: B3KY11
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: August 30, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.