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Protein
Submitted name:

cDNA FLJ45031 fis, clone BRAWH3018548, highly similar to Vinculin

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ45031 fis, clone BRAWH3018548, highly similar to VinculinImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37288.

PTM / Processingi

Proteomic databases

PeptideAtlasiB3KXA2.
PRIDEiB3KXA2.

Expressioni

Gene expression databases

GenevisibleiB3KXA2. HS.

Interactioni

GO - Molecular functioni

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili287 – 314Sequence analysisAdd BLAST28
Coiled coili951 – 974Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000007828.
HOVERGENiHBG079758.
KOiK05700.

Family and domain databases

InterProiView protein in InterPro
IPR036723. Alpha-catenin/vinculin-like_sf.
IPR017997. Vinculin.
IPR006077. Vinculin/catenin.
IPR000633. Vinculin_CS.
PANTHERiPTHR18914. PTHR18914. 2 hits.
PTHR18914:SF1. PTHR18914:SF1. 2 hits.
PfamiView protein in Pfam
PF01044. Vinculin. 2 hits.
SUPFAMiSSF47220. SSF47220. 6 hits.
PROSITEiView protein in PROSITE
PS00663. VINCULIN_1. 1 hit.
PS00664. VINCULIN_2. 2 hits.

Sequencei

Sequence statusi: Complete.

B3KXA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPAFIKVEN ACTKLVQAAQ MLQSDPYSVP ARDYLIDGSR GILSGTSDLL
60 70 80 90 100
LTFDEAEVRK IIRVCKGILE YLTVAEVVET MEDLVTYTKN LGPGMTKMAK
110 120 130 140 150
MIDERQQELT HQEHRVMLVN SMNTVKELLP VLISAMKIFV TTKNSKNQGI
160 170 180 190 200
EEALKNRNFT VEKMSAEINE IIRVLQLTSW DEDAWASKDT EAMKRALASI
210 220 230 240 250
DSKLNQAKGW LRDPSASPGD AGEQAIRQIL DEAGKVGELC AGKERREILG
260 270 280 290 300
TCKMLEQMTD QVADLRARGQ GSSPVAMQKA QQVSQGLDVL TAKVENAARK
310 320 330 340 350
LEAMTNSKQS IAKKIDAAQN WLADPNGGPE GEEQIRGALA EARKIAELCD
360 370 380 390 400
DPKERDDILR SLGEISALTS KLADLRRQGK GDSPEARALA KQVATALQNL
410 420 430 440 450
QTKTNRAVAN SRPAKAAVHL EGKIEQAQRW IDNPTVDDRG VGQAAIRGLV
460 470 480 490 500
AEGHRLANVM MGPYRQDLLA KCDRVDQLTA QLADLAARGE GESPQARALA
510 520 530 540 550
SQLQDSLKDL KARMQEAMTQ EVSDVFSDTT TPIKLLAVAA TAPPDAPNRE
560 570 580 590 600
EVFDERAANF ENHSGKLGAT AEKAAAVGTA NKSTVEGIQA SVKTARELTP
610 620 630 640 650
QVVSAARILL RNPGNQAAYE HFETMKNQWI DNVEKMTGLV DEAIDTKSLL
660 670 680 690 700
DASEEAIKKD LDKCKVAMAN IQPQMLVAGA TSIARRANRI LLAAKREVEN
710 720 730 740 750
SEDPKFREAV KAASDELSKT ISPMVMDAKA VAGNISDPGL QKSFLDSGYR
760 770 780 790 800
ILGAVAKVRE AFQPQEPDFP PPPPDLEQLR LTDELAPPKP PLPEGEVPPP
810 820 830 840 850
RPPPPEEKDE EFPEQKAGEV INQPMMMAAR QLHDEARKWS SKGNDIIAAA
860 870 880 890 900
KRMALLMAEM SRLVRGGSGT KRALIQCAKD IAKASDEVTR LAKEVAKQCT
910 920 930 940 950
DKRIRTNLLQ VCERIPTIST QLKILSTVKA TMLGRTNISD EESEQATEML
960 970 980 990 1000
VHNAQNLMQS VKETVRELKL LQSKFEQMLD LHCAGLERLP GTSRHLAEPG

WHRNLY
Length:1,006
Mass (Da):110,306
Last modified:September 2, 2008 - v1
Checksum:iBA2C56F9404FF44C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK126978 mRNA. Translation: BAG54414.1.
RefSeqiNP_003364.1. NM_003373.3.
NP_054706.1. NM_014000.2.
UniGeneiHs.643896.

Genome annotation databases

GeneIDi7414.
KEGGihsa:7414.

Similar proteinsi

Entry informationi

Entry nameiB3KXA2_HUMAN
AccessioniPrimary (citable) accession number: B3KXA2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: October 25, 2017
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.