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Protein
Submitted name:

cDNA FLJ45031 fis, clone BRAWH3018548, highly similar to Vinculin

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ45031 fis, clone BRAWH3018548, highly similar to VinculinImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37288.

PTM / Processingi

Proteomic databases

PeptideAtlasiB3KXA2.
PRIDEiB3KXA2.

Expressioni

Gene expression databases

GenevisibleiB3KXA2. HS.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili287 – 31428Sequence analysisAdd
BLAST
Coiled coili951 – 97424Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000007828.
HOVERGENiHBG079758.
KOiK05700.

Family and domain databases

InterProiIPR006077. Vinculin/catenin.
IPR000633. Vinculin_CS.
[Graphical view]
PANTHERiPTHR18914. PTHR18914. 4 hits.
PfamiPF01044. Vinculin. 2 hits.
[Graphical view]
SUPFAMiSSF47220. SSF47220. 6 hits.
PROSITEiPS00663. VINCULIN_1. 1 hit.
PS00664. VINCULIN_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3KXA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPAFIKVEN ACTKLVQAAQ MLQSDPYSVP ARDYLIDGSR GILSGTSDLL
60 70 80 90 100
LTFDEAEVRK IIRVCKGILE YLTVAEVVET MEDLVTYTKN LGPGMTKMAK
110 120 130 140 150
MIDERQQELT HQEHRVMLVN SMNTVKELLP VLISAMKIFV TTKNSKNQGI
160 170 180 190 200
EEALKNRNFT VEKMSAEINE IIRVLQLTSW DEDAWASKDT EAMKRALASI
210 220 230 240 250
DSKLNQAKGW LRDPSASPGD AGEQAIRQIL DEAGKVGELC AGKERREILG
260 270 280 290 300
TCKMLEQMTD QVADLRARGQ GSSPVAMQKA QQVSQGLDVL TAKVENAARK
310 320 330 340 350
LEAMTNSKQS IAKKIDAAQN WLADPNGGPE GEEQIRGALA EARKIAELCD
360 370 380 390 400
DPKERDDILR SLGEISALTS KLADLRRQGK GDSPEARALA KQVATALQNL
410 420 430 440 450
QTKTNRAVAN SRPAKAAVHL EGKIEQAQRW IDNPTVDDRG VGQAAIRGLV
460 470 480 490 500
AEGHRLANVM MGPYRQDLLA KCDRVDQLTA QLADLAARGE GESPQARALA
510 520 530 540 550
SQLQDSLKDL KARMQEAMTQ EVSDVFSDTT TPIKLLAVAA TAPPDAPNRE
560 570 580 590 600
EVFDERAANF ENHSGKLGAT AEKAAAVGTA NKSTVEGIQA SVKTARELTP
610 620 630 640 650
QVVSAARILL RNPGNQAAYE HFETMKNQWI DNVEKMTGLV DEAIDTKSLL
660 670 680 690 700
DASEEAIKKD LDKCKVAMAN IQPQMLVAGA TSIARRANRI LLAAKREVEN
710 720 730 740 750
SEDPKFREAV KAASDELSKT ISPMVMDAKA VAGNISDPGL QKSFLDSGYR
760 770 780 790 800
ILGAVAKVRE AFQPQEPDFP PPPPDLEQLR LTDELAPPKP PLPEGEVPPP
810 820 830 840 850
RPPPPEEKDE EFPEQKAGEV INQPMMMAAR QLHDEARKWS SKGNDIIAAA
860 870 880 890 900
KRMALLMAEM SRLVRGGSGT KRALIQCAKD IAKASDEVTR LAKEVAKQCT
910 920 930 940 950
DKRIRTNLLQ VCERIPTIST QLKILSTVKA TMLGRTNISD EESEQATEML
960 970 980 990 1000
VHNAQNLMQS VKETVRELKL LQSKFEQMLD LHCAGLERLP GTSRHLAEPG

WHRNLY
Length:1,006
Mass (Da):110,306
Last modified:September 2, 2008 - v1
Checksum:iBA2C56F9404FF44C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK126978 mRNA. Translation: BAG54414.1.
RefSeqiNP_003364.1. NM_003373.3.
NP_054706.1. NM_014000.2.
UniGeneiHs.643896.

Genome annotation databases

GeneIDi7414.
KEGGihsa:7414.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK126978 mRNA. Translation: BAG54414.1.
RefSeqiNP_003364.1. NM_003373.3.
NP_054706.1. NM_014000.2.
UniGeneiHs.643896.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiB3KXA2.
PRIDEiB3KXA2.

Protocols and materials databases

DNASUi7414.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7414.
KEGGihsa:7414.

Organism-specific databases

CTDi7414.
PharmGKBiPA37288.

Phylogenomic databases

HOGENOMiHOG000007828.
HOVERGENiHBG079758.
KOiK05700.

Miscellaneous databases

GenomeRNAii7414.

Gene expression databases

GenevisibleiB3KXA2. HS.

Family and domain databases

InterProiIPR006077. Vinculin/catenin.
IPR000633. Vinculin_CS.
[Graphical view]
PANTHERiPTHR18914. PTHR18914. 4 hits.
PfamiPF01044. Vinculin. 2 hits.
[Graphical view]
SUPFAMiSSF47220. SSF47220. 6 hits.
PROSITEiPS00663. VINCULIN_1. 1 hit.
PS00664. VINCULIN_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiB3KXA2_HUMAN
AccessioniPrimary (citable) accession number: B3KXA2
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: July 6, 2016
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.