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Protein
Submitted name:

cDNA FLJ44500 fis, clone UTERU3000828, highly similar to 116 kDa U5 small nuclear ribonucleoprotein component

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

RibonucleoproteinImported

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding, Viral nucleoproteinImported

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ44500 fis, clone UTERU3000828, highly similar to 116 kDa U5 small nuclear ribonucleoprotein componentImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Virion

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142671915.

PTM / Processingi

Proteomic databases

PaxDbiB3KX19.
PRIDEiB3KX19.

Expressioni

Gene expression databases

BgeeiB3KX19.
GenevisibleiB3KX19. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000392094.

Structurei

3D structure databases

ProteinModelPortaliB3KX19.
SMRiB3KX19. Positions 102-945.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini117 – 399283Tr-type G (guanine nucleotide-binding)InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0469. Eukaryota.
COG0480. LUCA.
HOVERGENiHBG001838.
KOiK12852.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
3.30.70.240. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR009022. EFG_III-V.
IPR000640. EFG_V.
IPR031950. EFTUD2_N.
IPR027417. P-loop_NTPase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR005517. Transl_elong_EFG/EF2_IV.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PfamiPF00679. EFG_C. 1 hit.
PF14492. EFG_II. 1 hit.
PF03764. EFG_IV. 1 hit.
PF16004. EFTUD2. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SMARTiSM00838. EFG_C. 1 hit.
SM00889. EFG_IV. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF54211. SSF54211. 1 hit.
SSF54980. SSF54980. 2 hits.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3KX19-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTDLYDEFG NYIGPELDSD EDDDELGRET KDLDEMDDDD DDDDVGDHDD
60 70 80 90 100
DHPGMEVVLH EVYGPEVETI VQEEDTQPLT EPIIKPVKTK KFTLMEQTLP
110 120 130 140 150
VTVYEMDFLA DLMDNSELIR NVTLCGHLHH GKTCFVDCLI EQTHPEIRKR
160 170 180 190 200
YDQDLCYTDI LFTEQERGVG IKSTPVTVVL PDTKGKSYLF NIMDTPGHVN
210 220 230 240 250
FSDEVTAGLR ISDGVVLFID AAEGVMLNTE RLIKHAVQER LAVTVCINKI
260 270 280 290 300
DRLILELKLP PTDAYYKLRH IVDEVNGLIS MYSTDENLIL SPLLGNVCFS
310 320 330 340 350
SSQYSICFTL GSFAKIYADT FGDINYQEFA KRLWGDIYFN PKTRKFTKKA
360 370 380 390 400
PTSSSQRSFV EFILEPLYKI LAQVVGDVDT SLPRTLDELG IHLTKEELKL
410 420 430 440 450
NIRPLLRLVC KKFFGEFTGF VDMCVQHIPS PKVGAKPKIE HTYTGGVDSD
460 470 480 490 500
LGEAMSDCDP DGPLMCHTTK MYSTDDGVQF HAFGRVLSGT IHAGQPVKVL
510 520 530 540 550
GENYTLEDEE DSQICTVGRL WISVARYHIE VNRVPAGNWV LIEGVDQPIV
560 570 580 590 600
KTATITEPRG NEEAQIFRPL KFNTTSVIKI AVEPVNPSEL PKMLDGLRKV
610 620 630 640 650
NKSYPSLTTK VEESGEHVIL GTGELYLDCV MHDLRKMYSE IDIKVADPVV
660 670 680 690 700
TFCETVVETS SLKCFAETPN KKNKITMIAE PLEKGLAEDI ENEVVQITWN
710 720 730 740 750
RKKLGEFFQT KYDWDLLAAR SIWAFGPDAT GPNILVDDTL PSEVDKALLG
760 770 780 790 800
SVKDSIVQGF QWGTREGPLC DELIRNVKFK ILDAVVAQEP LHRGGGQIIP
810 820 830 840 850
TARRVVYSAF LMATPRLMEP YYFVEVQAPA DCVSAVYTVL ARRRGHVTQD
860 870 880 890 900
APIPGSPLYT IKAFIPAIDS FGFETDLRTH TQGQAFSLSV FHHWQIVPGD
910 920 930 940 950
PLDKSIVIRP LEPQPAPHLA REFMIKTRRR KGLSEDVSIS KFFDDPMLLE
960
LAKQDVVLNY PM
Length:962
Mass (Da):108,210
Last modified:September 2, 2008 - v1
Checksum:i2F20F10787BA194F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK126464 mRNA. Translation: BAG54331.1.
RefSeqiNP_001136077.1. NM_001142605.1.
NP_004238.3. NM_004247.3.
UniGeneiHs.151787.

Genome annotation databases

GeneIDi9343.
KEGGihsa:9343.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK126464 mRNA. Translation: BAG54331.1.
RefSeqiNP_001136077.1. NM_001142605.1.
NP_004238.3. NM_004247.3.
UniGeneiHs.151787.

3D structure databases

ProteinModelPortaliB3KX19.
SMRiB3KX19. Positions 102-945.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000392094.

Proteomic databases

PaxDbiB3KX19.
PRIDEiB3KX19.

Protocols and materials databases

DNASUi9343.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9343.
KEGGihsa:9343.

Organism-specific databases

CTDi9343.
PharmGKBiPA142671915.

Phylogenomic databases

eggNOGiKOG0469. Eukaryota.
COG0480. LUCA.
HOVERGENiHBG001838.
KOiK12852.

Miscellaneous databases

GenomeRNAii9343.

Gene expression databases

BgeeiB3KX19.
GenevisibleiB3KX19. HS.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
3.30.70.240. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR009022. EFG_III-V.
IPR000640. EFG_V.
IPR031950. EFTUD2_N.
IPR027417. P-loop_NTPase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR005517. Transl_elong_EFG/EF2_IV.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PfamiPF00679. EFG_C. 1 hit.
PF14492. EFG_II. 1 hit.
PF03764. EFG_IV. 1 hit.
PF16004. EFTUD2. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SMARTiSM00838. EFG_C. 1 hit.
SM00889. EFG_IV. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF54211. SSF54211. 1 hit.
SSF54980. SSF54980. 2 hits.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: UterusImported.

Entry informationi

Entry nameiB3KX19_HUMAN
AccessioniPrimary (citable) accession number: B3KX19
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: June 8, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.