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Protein

T-complex protein 1 subunit gamma

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ChaperoneUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
T-complex protein 1 subunit gammaUniRule annotation
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26180.

PTM / Processingi

Proteomic databases

PaxDbiB3KX11.
PRIDEiB3KX11.

Expressioni

Gene expression databases

GenevisibleiB3KX11. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000295688.

Family & Domainsi

Sequence similaritiesi

Belongs to the TCP-1 chaperonin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0364. Eukaryota.
COG0459. LUCA.
HOGENOMiHOG000226732.
HOVERGENiHBG104982.
KOiK09495.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.30.260.10. 2 hits.
3.50.7.10. 1 hit.
InterProiIPR012719. Chap_CCT_gamma.
IPR017998. Chaperone_TCP-1.
IPR002194. Chaperonin_TCP-1_CS.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
[Graphical view]
PANTHERiPTHR11353:SF63. PTHR11353:SF63. 1 hit.
PfamiPF00118. Cpn60_TCP1. 2 hits.
[Graphical view]
PRINTSiPR00304. TCOMPLEXTCP1.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02344. chap_CCT_gamma. 1 hit.
PROSITEiPS00750. TCP1_1. 1 hit.
PS00751. TCP1_2. 1 hit.
PS00995. TCP1_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3KX11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMGHRPVLVL SQNTKRESGR KVQSGNINAA KTIADIIRTC LGPKSMMKML
60 70 80 90 100
LDPMGGIVMT NDGNAILREI QVQHPAAKSM IEISRTQDEE VGDGTTTVVI
110 120 130 140 150
SAYRKALDDM ISTLKKISIP VDISDSDMML NIINSSITTK AISRWSSLAC
160 170 180 190 200
NIALDAVKMV QFEENGRKEI DIKKYARVEK IPGGIIEDSC VLRGVMINKD
210 220 230 240 250
VTHPRMRRHI KNPRIVLLDS SLEYKKGESQ TDIEITREED FTRILQMEEE
260 270 280 290 300
YIQQLCEDII QLKPDVVITE KGISDLAQHY LMRANITAIR RVRKTDNNRI
310 320 330 340 350
ARACGARIVS RPEELREDDV GTGAGLLEIK KIGDEYFTFI TDCKDPKACT
360 370 380 390 400
ILLRGASKEI LSEVERNLQD AMQVCRNVLL DPQLVPGGGA SEMAVAHALT
410 420 430 440 450
EKSKAMTGVE QWPYRAVAQA LEVIPRTLIQ NCGASTIRLL TSLRAKHTQE
460 470 480 490 500
NCETWGVNGE TGTLVDMKEL GIWEPLAVKL QTYKTAVETA VLLLRIDDIV
510 520
SGHKKKGDDQ SRQGGAPDAG QE
Length:522
Mass (Da):57,946
Last modified:September 2, 2008 - v1
Checksum:iBC05982B7448414B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK126400 mRNA. Translation: BAG54323.1.
RefSeqiNP_001008800.1. NM_001008800.2.
NP_005989.3. NM_005998.4.
UniGeneiHs.491494.

Genome annotation databases

GeneIDi7203.
KEGGihsa:7203.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK126400 mRNA. Translation: BAG54323.1.
RefSeqiNP_001008800.1. NM_001008800.2.
NP_005989.3. NM_005998.4.
UniGeneiHs.491494.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000295688.

Proteomic databases

PaxDbiB3KX11.
PRIDEiB3KX11.

Protocols and materials databases

DNASUi7203.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7203.
KEGGihsa:7203.

Organism-specific databases

CTDi7203.
PharmGKBiPA26180.

Phylogenomic databases

eggNOGiKOG0364. Eukaryota.
COG0459. LUCA.
HOGENOMiHOG000226732.
HOVERGENiHBG104982.
KOiK09495.

Miscellaneous databases

GenomeRNAii7203.
NextBioi28226.

Gene expression databases

GenevisibleiB3KX11. HS.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.30.260.10. 2 hits.
3.50.7.10. 1 hit.
InterProiIPR012719. Chap_CCT_gamma.
IPR017998. Chaperone_TCP-1.
IPR002194. Chaperonin_TCP-1_CS.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
[Graphical view]
PANTHERiPTHR11353:SF63. PTHR11353:SF63. 1 hit.
PfamiPF00118. Cpn60_TCP1. 2 hits.
[Graphical view]
PRINTSiPR00304. TCOMPLEXTCP1.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02344. chap_CCT_gamma. 1 hit.
PROSITEiPS00750. TCP1_1. 1 hit.
PS00751. TCP1_2. 1 hit.
PS00995. TCP1_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: UterusImported.

Entry informationi

Entry nameiB3KX11_HUMAN
AccessioniPrimary (citable) accession number: B3KX11
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: May 11, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.