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Protein
Submitted name:

cDNA FLJ43092 fis, clone COLON2002520, highly similar to Myosin-14

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Motor protein, MyosinSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ43092 fis, clone COLON2002520, highly similar to Myosin-14Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134935217.

PTM / Processingi

Proteomic databases

PRIDEiB3KWH4.

Expressioni

Gene expression databases

GenevisibleiB3KWH4. HS.

Structurei

3D structure databases

ProteinModelPortaliB3KWH4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 436436Myosin motorInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili503 – 625123Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.SAAS annotation
Contains IQ domain.SAAS annotation
Contains myosin motor domain.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

HOGENOMiHOG000173958.
HOVERGENiHBG105641.
KOiK10352.

Family and domain databases

Gene3Di4.10.270.10. 1 hit.
InterProiIPR000048. IQ_motif_EF-hand-BS.
IPR027401. Myosin-like_IQ_dom.
IPR001609. Myosin_head_motor_dom.
IPR002928. Myosin_tail.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00612. IQ. 1 hit.
PF00063. Myosin_head. 1 hit.
PF01576. Myosin_tail_1. 1 hit.
[Graphical view]
PRINTSiPR00193. MYOSINHEAVY.
SMARTiSM00015. IQ. 1 hit.
SM00242. MYSc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS50096. IQ. 1 hit.
PS51456. MYOSIN_MOTOR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B3KWH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRMVSAVLQ FGNIALKRER NTDQATMPDN TAAQKLCRLL GLGVTDFSRA
60 70 80 90 100
LLTPRIKVGR DYVQKAQTKE QADFALEALA KATYERLFRW LVLRLNRALD
110 120 130 140 150
RSPRQGASFL GILDIAGFEI FQLNSFEQLC INYANEKLQQ LFNHTMFVLE
160 170 180 190 200
QEEYQREGIP WTFLDFGLDL QPCIDLIERP ANPPGLLALL DEECWFPKAT
210 220 230 240 250
DKSFVEKVAQ EQGGHPKFQR PRHLRDQADF SVLHYAGKVD YKANEWLMKN
260 270 280 290 300
MDPLNDNVAA LLHQSTDRLT AEIWKDVEGI VGLEQVSSLG DGPPGGRPRR
310 320 330 340 350
GMFRTVGQLY KESLSRLMAT LSNTNPSFVR CIVPNHEKRA GKLEPRLVLD
360 370 380 390 400
QLRCNGVLEG IRICRQGFPN RILFQEFRQR YEILTPNAIP KGFMDGKQAC
410 420 430 440 450
EKMIQALELD PNLYRVGQSK IFFRAGVLAQ LEEERDLKVT DIIVSFQAAA
460 470 480 490 500
RGYLARRAFQ KRQQQQSALR VMQRNCAAYL KLRHWQWWRL FTKVKPLLQV
510 520 530 540 550
TRQDEVLQAR AQELQKVQEL QQQSAREVGE LQGRVAQLEE ERARLAEQLR
560 570 580 590 600
AEAELCAEAE ETRGRLAARK QELELVVSEL EARVGEEEEC SRQMQTEKKR
610 620
LQQHIQELEA HLEAEEGARQ KLQLEKVTT
Length:629
Mass (Da):72,421
Last modified:September 2, 2008 - v1
Checksum:iC190905B10F85C71
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei629 – 6291Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125082 mRNA. Translation: BAG54136.1.
RefSeqiNP_001070654.1. NM_001077186.1.
NP_001139281.1. NM_001145809.1.
UniGeneiHs.467142.

Genome annotation databases

GeneIDi79784.
KEGGihsa:79784.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125082 mRNA. Translation: BAG54136.1.
RefSeqiNP_001070654.1. NM_001077186.1.
NP_001139281.1. NM_001145809.1.
UniGeneiHs.467142.

3D structure databases

ProteinModelPortaliB3KWH4.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiB3KWH4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi79784.
KEGGihsa:79784.

Organism-specific databases

CTDi79784.
PharmGKBiPA134935217.

Phylogenomic databases

HOGENOMiHOG000173958.
HOVERGENiHBG105641.
KOiK10352.

Miscellaneous databases

GenomeRNAii79784.

Gene expression databases

GenevisibleiB3KWH4. HS.

Family and domain databases

Gene3Di4.10.270.10. 1 hit.
InterProiIPR000048. IQ_motif_EF-hand-BS.
IPR027401. Myosin-like_IQ_dom.
IPR001609. Myosin_head_motor_dom.
IPR002928. Myosin_tail.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00612. IQ. 1 hit.
PF00063. Myosin_head. 1 hit.
PF01576. Myosin_tail_1. 1 hit.
[Graphical view]
PRINTSiPR00193. MYOSINHEAVY.
SMARTiSM00015. IQ. 1 hit.
SM00242. MYSc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS50096. IQ. 1 hit.
PS51456. MYOSIN_MOTOR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: ColonImported.

Entry informationi

Entry nameiB3KWH4_HUMAN
AccessioniPrimary (citable) accession number: B3KWH4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: June 8, 2016
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.