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Protein
Submitted name:

cDNA FLJ43092 fis, clone COLON2002520, highly similar to Myosin-14

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin-bindingPROSITE-ProRule annotation, Motor protein, MyosinPROSITE-ProRule annotationSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ43092 fis, clone COLON2002520, highly similar to Myosin-14Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134935217

PTM / Processingi

Proteomic databases

PeptideAtlasiB3KWH4
PRIDEiB3KWH4

Expressioni

Gene expression databases

GenevisibleiB3KWH4 HS

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliB3KWH4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 436Myosin motorInterPro annotationAdd BLAST436

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni314 – 336Actin-bindingPROSITE-ProRule annotationAdd BLAST23

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili503 – 625Sequence analysisAdd BLAST123

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

HOGENOMiHOG000173958
HOVERGENiHBG105641

Family and domain databases

Gene3Di3.40.850.10, 2 hits
4.10.270.10, 1 hit
InterProiView protein in InterPro
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR001609 Myosin_head_motor_dom
IPR027401 Myosin_IQ_contain_sf
IPR002928 Myosin_tail
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00612 IQ, 1 hit
PF00063 Myosin_head, 1 hit
PF01576 Myosin_tail_1, 1 hit
PRINTSiPR00193 MYOSINHEAVY
SMARTiView protein in SMART
SM00015 IQ, 1 hit
SM00242 MYSc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50096 IQ, 1 hit
PS51456 MYOSIN_MOTOR, 1 hit

Sequencei

Sequence statusi: Fragment.

B3KWH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRMVSAVLQ FGNIALKRER NTDQATMPDN TAAQKLCRLL GLGVTDFSRA
60 70 80 90 100
LLTPRIKVGR DYVQKAQTKE QADFALEALA KATYERLFRW LVLRLNRALD
110 120 130 140 150
RSPRQGASFL GILDIAGFEI FQLNSFEQLC INYANEKLQQ LFNHTMFVLE
160 170 180 190 200
QEEYQREGIP WTFLDFGLDL QPCIDLIERP ANPPGLLALL DEECWFPKAT
210 220 230 240 250
DKSFVEKVAQ EQGGHPKFQR PRHLRDQADF SVLHYAGKVD YKANEWLMKN
260 270 280 290 300
MDPLNDNVAA LLHQSTDRLT AEIWKDVEGI VGLEQVSSLG DGPPGGRPRR
310 320 330 340 350
GMFRTVGQLY KESLSRLMAT LSNTNPSFVR CIVPNHEKRA GKLEPRLVLD
360 370 380 390 400
QLRCNGVLEG IRICRQGFPN RILFQEFRQR YEILTPNAIP KGFMDGKQAC
410 420 430 440 450
EKMIQALELD PNLYRVGQSK IFFRAGVLAQ LEEERDLKVT DIIVSFQAAA
460 470 480 490 500
RGYLARRAFQ KRQQQQSALR VMQRNCAAYL KLRHWQWWRL FTKVKPLLQV
510 520 530 540 550
TRQDEVLQAR AQELQKVQEL QQQSAREVGE LQGRVAQLEE ERARLAEQLR
560 570 580 590 600
AEAELCAEAE ETRGRLAARK QELELVVSEL EARVGEEEEC SRQMQTEKKR
610 620
LQQHIQELEA HLEAEEGARQ KLQLEKVTT
Length:629
Mass (Da):72,421
Last modified:September 2, 2008 - v1
Checksum:iC190905B10F85C71
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei629Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125082 mRNA Translation: BAG54136.1
RefSeqiNP_001070654.1, NM_001077186.1
NP_001139281.1, NM_001145809.1
UniGeneiHs.467142

Genome annotation databases

GeneIDi79784

Similar proteinsi

Entry informationi

Entry nameiB3KWH4_HUMAN
AccessioniPrimary (citable) accession number: B3KWH4
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: April 25, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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