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Protein
Submitted name:

Receptor tyrosine-protein kinase erbB-3

Gene

ERBB3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionKinaseImported, ReceptorImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Receptor tyrosine-protein kinase erbB-3Imported
Submitted name:
cDNA FLJ43038 fis, clone BRTHA3002955, highly similar to Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1)Imported
Gene namesi
Name:ERBB3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000065361.14
HGNCiHGNC:3431 ERBB3

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000065361
PharmGKBiPA27846

PTM / Processingi

Proteomic databases

MaxQBiB3KWG5
PeptideAtlasiB3KWG5
PRIDEiB3KWG5

Expressioni

Gene expression databases

BgeeiENSG00000065361
ExpressionAtlasiB3KWG5 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 84Pkinase_TyrInterPro annotationAdd BLAST67

Phylogenomic databases

eggNOGiKOG1025 Eukaryota
ENOG410XNSR LUCA
GeneTreeiENSGT00760000118799
HOGENOMiHOG000065773
HOVERGENiHBG103459

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
PfamiView protein in Pfam
PF07714 Pkinase_Tyr, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit

Sequencei

Sequence statusi: Complete.

B3KWG5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPMSTILPVT SPCLPATGVT VWELMTFGAE PYAGLRLAEV PDLLEKGERL
60 70 80 90 100
AQPQICTIDV YMVMVKCWMI DENIRPTFKE LANEFTRMAR DPPRYLVIKR
110 120 130 140 150
ESGPGIAPGP EPHGLTNKKL EEVELEPELD LDLDLEAEED NLATTTLGSA
160 170 180 190 200
LSLPVGTLNR PRGSQSLLSP SSGYMPMNQG NLGESCQESA VSGSSERCPR
210 220 230 240 250
PVSLHPMPRG CLASESSEGH VTGSEAELQE KVSMCRSRSR SRSPRPRGDS
260 270 280 290 300
AYHSQRHSLL TPVTPLSPPG LEEEDVNGYV MPDTHLKGTP SSREGTLSSV
310 320 330 340 350
GLSSVLGTEE EDEDEEYEYM NRRRRHSPPH PPRPSSLEEL GYEYMDVGSD
360 370 380 390 400
LSASLGSTQS CPLHPVPIMP TAGTTPDEDY EYMNRQRDGG GPGGDYAAMG
410 420 430 440 450
ACPASEQGYE EMRAFQGPGH QAPHVHYARL KTLRSLEATD SAFDNPDYWH
460
SRLFPKANAQ RT
Length:462
Mass (Da):50,653
Last modified:September 2, 2008 - v1
Checksum:i7DABEF89C435689A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC034102 Genomic DNA No translation available.
AK125028 mRNA Translation: BAG54127.1
UniGeneiHs.118681
Hs.622058

Genome annotation databases

EnsembliENST00000549832; ENSP00000448729; ENSG00000065361
UCSCiuc001sjl.4 human

Similar proteinsi

Entry informationi

Entry nameiB3KWG5_HUMAN
AccessioniPrimary (citable) accession number: B3KWG5
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: May 23, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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