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Protein
Submitted name:

cDNA FLJ42993 fis, clone BRTHA2010884, highly similar to ADAMTS-13

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. endopeptidase activity Source: Ensembl

GO - Biological processi

  1. response to interferon-gamma Source: Ensembl
  2. response to interleukin-4 Source: Ensembl
  3. response to toxic substance Source: Ensembl
  4. response to tumor necrosis factor Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ42993 fis, clone BRTHA2010884, highly similar to ADAMTS-13Imported (EC:3.4.24.-Imported)
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: Ensembl
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24539.

Expressioni

Gene expression databases

BgeeiB3KWF7.
ExpressionAtlasiB3KWF7. baseline and differential.

Interactioni

Family & Domainsi

Family and domain databases

InterProiIPR000859. CUB_dom.
IPR000884. Thrombospondin_1_rpt.
[Graphical view]
PfamiPF00090. TSP_1. 2 hits.
[Graphical view]
SMARTiSM00209. TSP1. 1 hit.
[Graphical view]
SUPFAMiSSF49854. SSF49854. 2 hits.
SSF82895. SSF82895. 2 hits.
PROSITEiPS50092. TSP1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3KWF7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSLGPCSASC GLGTARRSVA CVQLDQGQDV EVDEAACAAL VRPEASVPCL
60 70 80 90 100
IADCTYRWHV GTWMECSVSC GDGIQRRRDT CLGPQAQAPV PADFCQHLPK
110 120 130 140 150
PVTVRGCWAG PCVGQGTPSL VPHEEAAAPG RTTATPAGAS LEWSQARGLL
160 170 180 190 200
FSPAPQPRRL LPGPQENSVQ SSACGRQHLE PTGTIDMRGP GQADCAVAIG
210 220 230 240 250
RPLGEVVTLR VLESSLNCSA GDMLLLWGRL TWRKMCRKLL DMTFSSKTNT
260 270 280 290 300
LVVRQRCGRP GGGVLLRYGS QLAPETFYRE CDMQLFGPWG EIVSPSLSPA
310 320 330 340 350
TSNAGGCRLF INVAPHARIA IHALATNMGA GTEGANASYI LIRDTHSLRT
360 370 380 390 400
TAFHGQQVLY WESESSQAEM EFSEGFLKAQ ASLRGQYWTL QSWVPEMQDP

QSWKGKEGT
Length:409
Mass (Da):44,000
Last modified:September 2, 2008 - v1
Checksum:i10B107236ACA5242
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK124983 mRNA. Translation: BAG54119.1.
UniGeneiHs.131433.

Genome annotation databases

UCSCiuc004ceb.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK124983 mRNA. Translation: BAG54119.1.
UniGeneiHs.131433.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Chemistry

BindingDBiB3KWF7.

Protocols and materials databases

DNASUi11093.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiuc004ceb.4. human.

Organism-specific databases

PharmGKBiPA24539.

Miscellaneous databases

NextBioi42166.

Gene expression databases

BgeeiB3KWF7.
ExpressionAtlasiB3KWF7. baseline and differential.

Family and domain databases

InterProiIPR000859. CUB_dom.
IPR000884. Thrombospondin_1_rpt.
[Graphical view]
PfamiPF00090. TSP_1. 2 hits.
[Graphical view]
SMARTiSM00209. TSP1. 1 hit.
[Graphical view]
SUPFAMiSSF49854. SSF49854. 2 hits.
SSF82895. SSF82895. 2 hits.
PROSITEiPS50092. TSP1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: ThalamusImported.

Entry informationi

Entry nameiB3KWF7_HUMAN
AccessioniPrimary (citable) accession number: B3KWF7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: November 26, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.