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Protein
Submitted name:

cDNA FLJ42779 fis, clone BRAWH3005300, highly similar to Exportin-1

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ42779 fis, clone BRAWH3005300, highly similar to Exportin-1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37418.

PTM / Processingi

Proteomic databases

PaxDbiB3KWD0.
PeptideAtlasiB3KWD0.
PRIDEiB3KWD0.

Expressioni

Gene expression databases

BgeeiB3KWD0.
GenevisibleiB3KWD0. HS.

Interactioni

Protein-protein interaction databases

IntActiB3KWD0. 1 interaction.
STRINGi9606.ENSP00000384863.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini356 – 674319CRM1_CInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG2020. Eukaryota.
COG5101. LUCA.
HOVERGENiHBG052817.
KOiK14290.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR014877. CRM1_C_dom.
[Graphical view]
PfamiPF08767. CRM1_C. 1 hit.
[Graphical view]
SMARTiSM01102. CRM1_C. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.

Sequencei

Sequence statusi: Complete.

B3KWD0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLVSEVEET EIFKICLEYW NHLAAELYRE SPFSTSASPL LSGSQHFDVP
60 70 80 90 100
PRRQLYLPML FKVRLLMVSR MAKPEEVLVV ENDQGEVVRE FMKDTDSINL
110 120 130 140 150
YKNMRETLVY LTHLDYVDTE RIMTEKLHNQ VNGTEWSWKN LNTLCWAIGS
160 170 180 190 200
ISGAMHEEDE KRFLVTVIKD LLGLCEQKRG KDNKAIIASN IMYIVGQYPR
210 220 230 240 250
FLRAHWKFLK TVVNKLFEFM HETHDGVQDM ACDTFIKIAQ KCRRHFVQVQ
260 270 280 290 300
VGEVMPFIDE ILNNINTIIC DLQPQQVHTF YEAVGYMIGA QTDQTVQEHL
310 320 330 340 350
IEKYMLLPNQ VWDSIIQQAT KNVDILKDPE TVKQLGSILK TNVRACKAVG
360 370 380 390 400
HPFVIQLGRI YLDMLNVYKC LSENISAAIQ ANGEMVTKQP LIRSMRTVKR
410 420 430 440 450
ETLKLISGWV SRSNDPQMVA ENFVPPLLDA VLIDYQRNVP AAREPEVLST
460 470 480 490 500
MAIIVNKLGG HITAEIPQIF DAVFECTLNM INKDFEEYPE HRTNFFLLLQ
510 520 530 540 550
AVNSHCFPAF LAIPPTQFKL VLDSIIWAFK HTMRNVADTG LQILFTLLQN
560 570 580 590 600
VAQEEAAAQS FYQTYFCDIL QHIFSVVTDT SHTAGLTMHA SILAYMFNLV
610 620 630 640 650
EEGKISTSLN PGNPVNNQIF LQEYVANLLK SAFPHLQDAQ VKLFVTGLFS
660 670 680 690 700
LNQDIPAFKE HLRDFLVQIK EFAGEDTSDL FLEEREIALR QADEEKHKRQ
710
MSVPGIFNPH EIPEEMCD
Length:718
Mass (Da):82,419
Last modified:September 2, 2008 - v1
Checksum:iEC4DF6C52E249A8E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK124769 mRNA. Translation: BAG54092.1.
RefSeqiNP_003391.1. NM_003400.3.
UniGeneiHs.370770.

Genome annotation databases

GeneIDi7514.
KEGGihsa:7514.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK124769 mRNA. Translation: BAG54092.1.
RefSeqiNP_003391.1. NM_003400.3.
UniGeneiHs.370770.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiB3KWD0. 1 interaction.
STRINGi9606.ENSP00000384863.

Proteomic databases

PaxDbiB3KWD0.
PeptideAtlasiB3KWD0.
PRIDEiB3KWD0.

Protocols and materials databases

DNASUi7514.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7514.
KEGGihsa:7514.

Organism-specific databases

CTDi7514.
PharmGKBiPA37418.

Phylogenomic databases

eggNOGiKOG2020. Eukaryota.
COG5101. LUCA.
HOVERGENiHBG052817.
KOiK14290.

Miscellaneous databases

GenomeRNAii7514.

Gene expression databases

BgeeiB3KWD0.
GenevisibleiB3KWD0. HS.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR014877. CRM1_C_dom.
[Graphical view]
PfamiPF08767. CRM1_C. 1 hit.
[Graphical view]
SMARTiSM01102. CRM1_C. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiB3KWD0_HUMAN
AccessioniPrimary (citable) accession number: B3KWD0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: July 6, 2016
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.