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Protein
Submitted name:

cDNA FLJ42748 fis, clone BRAWH3000329, highly similar to Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ42748 fis, clone BRAWH3000329, highly similar to Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiB3KWC4.

Expressioni

Gene expression databases

GenevisibleiB3KWC4. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000013125.

Chemistry

BindingDBiB3KWC4.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini180 – 493314CNHInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0576. Eukaryota.
ENOG410XP9G. LUCA.
HOVERGENiHBG036702.
KOiK08833.

Family and domain databases

InterProiIPR001180. CNH_dom.
IPR021160. MAPKKKK.
[Graphical view]
PfamiPF00780. CNH. 1 hit.
[Graphical view]
PIRSFiPIRSF038172. MAPKKKK. 1 hit.
SMARTiSM00036. CNH. 1 hit.
[Graphical view]
PROSITEiPS50219. CNH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3KWC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSLYIPVIY FAVDKLQFEP PLRKETEARD EMGLSSDPNF MLQWNPFVDG
60 70 80 90 100
ANTGKSTSKR AIPPPLPPKP RISSYPEDNF PDEEKASTIK HCPDSESRAP
110 120 130 140 150
QILRRQSSPS CGPVAETSSI GNGDGISKLM SENTEGSAQA PQLPRKKDKR
160 170 180 190 200
DFPKPAINGL PPTPKVLMGA CFSKVFDGCP LKINCATSWI HPDTKDQYII
210 220 230 240 250
FGTEDGIYTL NLNELHEATM EQLFPRKCTW LYVINNTLMS LSEGKTFQLY
260 270 280 290 300
SHNLIALFEH AKKPGLAAHI QTHRFPDRIL PRKFALTTKI PDTKGCHKCC
310 320 330 340 350
IVRNPYTGHK YLCGALQSGI VLLQWYEPMQ KFMLIKHFDF PLPSPLNVFE
360 370 380 390 400
MLVIPEQEYP MVCVAISKGT ESNQVVQFET INLNSASSWF TEIGAGSQQL
410 420 430 440 450
DSIHVTQLER DTVLVCLDKF VKIVNLQGKL KSSKKLASEL SFDFRIESVV
460 470 480 490 500
CLQDSVLAFW KHGMQGKSFK SDEVTQEISD ETRVFRLLGS DRVVVLESRP
510 520
TENPTAHSNL YILAGHENSY
Length:520
Mass (Da):58,445
Last modified:September 2, 2008 - v1
Checksum:i7228BE1D810A8D55
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK124738 mRNA. Translation: BAG54086.1.
RefSeqiNP_006566.2. NM_006575.4.
NP_942089.1. NM_198794.2.
UniGeneiHs.130491.

Genome annotation databases

GeneIDi11183.
KEGGihsa:11183.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK124738 mRNA. Translation: BAG54086.1.
RefSeqiNP_006566.2. NM_006575.4.
NP_942089.1. NM_198794.2.
UniGeneiHs.130491.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000013125.

Chemistry

BindingDBiB3KWC4.

Proteomic databases

PaxDbiB3KWC4.

Protocols and materials databases

DNASUi11183.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi11183.
KEGGihsa:11183.

Organism-specific databases

CTDi11183.

Phylogenomic databases

eggNOGiKOG0576. Eukaryota.
ENOG410XP9G. LUCA.
HOVERGENiHBG036702.
KOiK08833.

Miscellaneous databases

GenomeRNAii11183.
NextBioi42555.

Gene expression databases

GenevisibleiB3KWC4. HS.

Family and domain databases

InterProiIPR001180. CNH_dom.
IPR021160. MAPKKKK.
[Graphical view]
PfamiPF00780. CNH. 1 hit.
[Graphical view]
PIRSFiPIRSF038172. MAPKKKK. 1 hit.
SMARTiSM00036. CNH. 1 hit.
[Graphical view]
PROSITEiPS50219. CNH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiB3KWC4_HUMAN
AccessioniPrimary (citable) accession number: B3KWC4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: March 16, 2016
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.