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Protein
Submitted name:

cDNA FLJ41851 fis, clone NT2RI3003925, highly similar to Endothelial PAS domain-containing protein 1

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: Ensembl
  2. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Source: Ensembl

GO - Biological processi

  1. angiogenesis Source: Ensembl
  2. blood vessel remodeling Source: Ensembl
  3. cell maturation Source: Ensembl
  4. embryonic placenta development Source: Ensembl
  5. erythrocyte differentiation Source: Ensembl
  6. lung development Source: Ensembl
  7. mitochondrion organization Source: Ensembl
  8. myoblast fate commitment Source: Ensembl
  9. norepinephrine metabolic process Source: Ensembl
  10. regulation of heart rate Source: Ensembl
  11. regulation of transcription from RNA polymerase II promoter in response to oxidative stress Source: Ensembl
  12. surfactant homeostasis Source: Ensembl
  13. visual perception Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ41851 fis, clone NT2RI3003925, highly similar to Endothelial PAS domain-containing protein 1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. nucleus Source: Ensembl
  3. transcription factor complex Source: Ensembl
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27809.

Expressioni

Gene expression databases

BgeeiB3KW07.
ExpressionAtlasiB3KW07. baseline and differential.

Interactioni

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG101948.
KOiK09095.

Family and domain databases

InterProiIPR014887. HIF-1_TAD_C.
[Graphical view]
PfamiPF08778. HIF-1a_CTAD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3KW07-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDGEDFQLSP ICPEERLLAE NPQSTPQHCF SAMTNIFQPL APVAPHSPFL
60 70 80 90 100
LDKFQQQLES KKTEPEHRPM SSIFFDAGSK ASLPPCCGQA STPLSSMGGR
110 120 130 140 150
SNTQWPPDPP LHFGPTKWAV GDQRTEFLGA APLGPPVSPP HVSTFKTRSA
160 170 180 190 200
KGFGARGPDV LSPAMVALSN KLKLKRQLEY EEQAFQDLSG GDPPGGSTSH
210 220 230 240 250
LMWKRMKNLR GGSCPLMPDK PLSANVPNDK FTQNPMRGLG HPLRHLPLPQ
260 270 280 290 300
PPSAISPGEN SKSRFPPQCY ATQYQDYSLS SAHKVSGMAS RLLGPSFESY
310 320 330
LLPELTRYDC EVNVPVLGSS TLLQGGDLLR ALDQAT
Length:336
Mass (Da):36,509
Last modified:September 2, 2008 - v1
Checksum:iD5C86DD03FDE0B34
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK123845 mRNA. Translation: BAG53969.1.
RefSeqiNP_001421.2. NM_001430.4.
UniGeneiHs.468410.

Genome annotation databases

GeneIDi2034.
KEGGihsa:2034.
UCSCiuc002ruw.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK123845 mRNA. Translation: BAG53969.1.
RefSeqiNP_001421.2. NM_001430.4.
UniGeneiHs.468410.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Chemistry

BindingDBiB3KW07.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2034.
KEGGihsa:2034.
UCSCiuc002ruw.3. human.

Organism-specific databases

CTDi2034.
PharmGKBiPA27809.

Phylogenomic databases

HOVERGENiHBG101948.
KOiK09095.

Miscellaneous databases

GenomeRNAii2034.
NextBioi8255.

Gene expression databases

BgeeiB3KW07.
ExpressionAtlasiB3KW07. baseline and differential.

Family and domain databases

InterProiIPR014887. HIF-1_TAD_C.
[Graphical view]
PfamiPF08778. HIF-1a_CTAD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiB3KW07_HUMAN
AccessioniPrimary (citable) accession number: B3KW07
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: November 26, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.