Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cysteine protease

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Thiol proteaseSAAS annotation
Biological processAutophagyUniRule annotationSAAS annotation, Protein transportUniRule annotationSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Cysteine proteaseUniRule annotation (EC:3.4.22.-UniRule annotation)
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

MaxQBiB3KVU2
PeptideAtlasiB3KVU2

Expressioni

Gene expression databases

GenevisibleiB3KVU2 HS

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase C54 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2674 Eukaryota
ENOG410XPQ0 LUCA
KOiK08342

Family and domain databases

InterProiView protein in InterPro
IPR032916 ATG4B_met
IPR005078 Peptidase_C54
PANTHERiPTHR22624 PTHR22624, 1 hit
PTHR22624:SF39 PTHR22624:SF39, 1 hit
PfamiView protein in Pfam
PF03416 Peptidase_C54, 1 hit

Sequencei

Sequence statusi: Complete.

B3KVU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPPLSLSSA GSATHLPTCL ILPGEELIYL DPHTTQPAVE PTDGCFIPDE
60 70 80 90 100
SFHCQHPPCR MSIAELDPSI AVGFFCKTED DFNDWCQQVK KLSLLGGALP
110 120 130 140
MFELVELQPS HLACPDVLNL SLDSSDVERL ERFFDSEDED FEILSL
Length:146
Mass (Da):16,221
Last modified:September 2, 2008 - v1
Checksum:i0A3C1A20A98CCF4B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK123425 mRNA Translation: BAG53904.1
RefSeqiNP_037457.3, NM_013325.4
UniGeneiHs.283610

Genome annotation databases

GeneIDi23192
KEGGihsa:23192

Entry informationi

Entry nameiB3KVU2_HUMAN
AccessioniPrimary (citable) accession number: B3KVU2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: May 23, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health