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Protein
Submitted name:

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

Gene

GNB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Imported
Submitted name:
cDNA FLJ16663 fis, clone THYMU2005759, highly similar to Guanine nucleotide-binding proteinG(I)/G(S)/G(T) subunit beta 1Imported
Gene namesi
Name:GNB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:4396. GNB1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000078369.

PTM / Processingi

Proteomic databases

MaxQBiB3KVK2.

Expressioni

Gene expression databases

BgeeiENSG00000078369.
ExpressionAtlasiB3KVK2. baseline and differential.

Structurei

3D structure databases

SMRiB3KVK2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 240WD_REPEATS_REGIONInterPro annotationAdd BLAST240
Repeati39 – 79WDPROSITE-ProRule annotationAdd BLAST41
Repeati80 – 121WDPROSITE-ProRule annotationAdd BLAST42
Repeati122 – 163WDPROSITE-ProRule annotationAdd BLAST42
Repeati173 – 198WDPROSITE-ProRule annotationAdd BLAST26
Repeati208 – 240WDPROSITE-ProRule annotationAdd BLAST33

Keywords - Domaini

WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0286. Eukaryota.
ENOG410XQUX. LUCA.
GeneTreeiENSGT00760000119239.
HOVERGENiHBG000188.

Family and domain databases

Gene3Di2.130.10.10. 3 hits.
InterProiView protein in InterPro
IPR020472. G-protein_beta_WD-40_rep.
IPR016346. Guanine_nucleotide-bd_bsu.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
PANTHERiPTHR19850. PTHR19850. 1 hit.
PfamiView protein in Pfam
PF00400. WD40. 5 hits.
PRINTSiPR00320. GPROTEINBRPT.
SMARTiView protein in SMART
SM00320. WD40. 5 hits.
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiView protein in PROSITE
PS00678. WD_REPEATS_1. 2 hits.
PS50082. WD_REPEATS_2. 5 hits.
PS50294. WD_REPEATS_REGION. 1 hit.

Sequencei

Sequence statusi: Complete.

B3KVK2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTCAYAPSGN YVACGGLDNI CSIYNLKTRE GNVRVSRELA GHTGYLSCCR
60 70 80 90 100
FLDDNQIVTS SGDTTCALWD IETGQQTTTF TGHTGDVMSL SLAPDTRLFV
110 120 130 140 150
SGACDASAKL WDVREGMCRQ TFTGHESDIN AICFFPNGNA FATGSDDATC
160 170 180 190 200
RLFDLRADQE LMTYSHDNII CGITSVSFSK SGRLLLAGYD DFNCNVWDAL
210 220 230 240
KADRAGVLAG HDNRVSCLGV TDDGMAVATG SWDSFLKIWN
Length:240
Mass (Da):25,935
Last modified:September 2, 2008 - v1
Checksum:i372B5998DF3B8414
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL031282 Genomic DNA. No translation available.
AL109917 Genomic DNA. No translation available.
KF495846 Genomic DNA. No translation available.
AK122949 mRNA. Translation: BAG53814.1.
RefSeqiNP_001269467.1. NM_001282538.1.
UniGeneiHs.430425.
Hs.721030.

Genome annotation databases

EnsembliENST00000615252; ENSP00000483532; ENSG00000078369.
GeneIDi2782.
UCSCiuc009vky.4. human.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiB3KVK2_HUMAN
AccessioniPrimary (citable) accession number: B3KVK2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: July 5, 2017
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported