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B3KUG6

- B3KUG6_HUMAN

UniProt

B3KUG6 - B3KUG6_HUMAN

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Protein
Submitted name:

cDNA FLJ39849 fis, clone SPLEN2014711, highly similar to Homo sapiens hect domain and RLD 6 (HERC6), transcript variant 1, mRNA

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. ubiquitin-protein transferase activity Source: InterPro

GO - Biological processi

  1. hematopoietic progenitor cell differentiation Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotation

Keywords - Biological processi

Ubl conjugation pathwaySAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ39849 fis, clone SPLEN2014711, highly similar to Homo sapiens hect domain and RLD 6 (HERC6), transcript variant 1, mRNAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Expressioni

Gene expression databases

BgeeiB3KUG6.
ExpressionAtlasiB3KUG6. baseline and differential.

Family & Domainsi

Sequence similaritiesi

Contains HECT (E6AP-type E3 ubiquitin-protein ligase) domain.SAAS annotation

Phylogenomic databases

HOVERGENiHBG103705.

Family and domain databases

InterProiIPR000569. HECT.
[Graphical view]
PfamiPF00632. HECT. 1 hit.
[Graphical view]
SMARTiSM00119. HECTc. 1 hit.
[Graphical view]
SUPFAMiSSF56204. SSF56204. 1 hit.
PROSITEiPS50237. HECT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3KUG6-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MARDTFKKLT KKEWISSMIT TCLEDDLLRA LPCHSPHQEA LSVFLLLPEC
60 70 80 90 100
PVMHDSKNWK NLVVPFAKAV CEMSKQSLQV LKKCWAFLQE SSLNPLIQML
110 120 130 140 150
KAAIISQLLH QTKTEQDHCN VKALLGMMKE LHKVNKANCR LPENTFNINE
160 170 180 190 200
LSNLLNFYID RGRQLFRDNH LIPAETPSPV IFSDFPFIFN SLSKIKLLQA
210 220 230 240 250
DSHIKMQMSE KKAYMLMHET ILQKKDEFPP SPRFILRVRR SRLVKDALRQ
260 270 280 290 300
LSQAEATDFC KVLVVEFINE ICPESGGVSS EFFHCMFEEM TKPEYGMFMY
310 320 330 340 350
PEMGSCMWFP AKPKPEKKRY FLFGMLCGLS LFNLNVANLP FPLALYKKLL
360 370 380 390 400
DQKPSLEDLK ELSPRLGKSL QEVLDDAADD IGDALCIRFS IHWDQNDVDL
410 420 430 440 450
IPNGISIPVD QTNKRDYVSK YIDYIFNVSV KAVYEEFQRG FYRVCEKEIL
460 470 480 490 500
RHFYPEELMT AIIGNTDYDW KQFEQNSKYE QGYQKSHPTI QLFWKAFHKL
510 520 530 540 550
TLDEKKKFLF FLTGRDRLHA RGIQKMEIVF RCPETFSERD HPTSITCHNI
560 570 580
LSLPKYSTME RMEEALQVAI NNNRGFVSPM LTQS
Length:584
Mass (Da):68,049
Last modified:September 2, 2008 - v1
Checksum:i720879865BF1D22D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK097168 mRNA. Translation: BAG53428.1.
UniGeneiHs.529317.

Genome annotation databases

UCSCiuc011cdl.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK097168 mRNA. Translation: BAG53428.1 .
UniGenei Hs.529317.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc011cdl.3. human.

Phylogenomic databases

HOVERGENi HBG103705.

Miscellaneous databases

NextBioi 35470080.

Gene expression databases

Bgeei B3KUG6.
ExpressionAtlasi B3KUG6. baseline and differential.

Family and domain databases

InterProi IPR000569. HECT.
[Graphical view ]
Pfami PF00632. HECT. 1 hit.
[Graphical view ]
SMARTi SM00119. HECTc. 1 hit.
[Graphical view ]
SUPFAMi SSF56204. SSF56204. 1 hit.
PROSITEi PS50237. HECT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: SpleenImported.

Entry informationi

Entry nameiB3KUG6_HUMAN
AccessioniPrimary (citable) accession number: B3KUG6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: October 29, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.