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Protein
Submitted name:

Apolipoprotein L, 6

Gene

ApoL6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Apolipoprotein L, 6Imported
Submitted name:
Apolipoprotein L6Imported
Submitted name:
cDNA FLJ38562 fis, clone HCHON2004002, highly similar to Apolipoprotein-L6Imported
Gene namesi
Name:ApoL6Imported
Synonyms:APOL6Imported
ORF Names:hCG_1648009Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000221963.5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei79 – 101HelicalSequence analysisAdd BLAST23
Transmembranei107 – 126HelicalSequence analysisAdd BLAST20
Transmembranei324 – 342HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24909

PTM / Processingi

Keywords - PTMi

LipoproteinImported

Expressioni

Gene expression databases

BgeeiENSG00000221963
ExpressionAtlasiB3KTP4 baseline and differential

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

IntActiB3KTP4, 4 interactors

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili50 – 70Sequence analysisAdd BLAST21
Coiled coili268 – 295Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IWES Eukaryota
ENOG410Y0AF LUCA
HOVERGENiHBG106550
KOiK14480
OMAiTHKKFTK
OrthoDBiEOG091G0SMD

Family and domain databases

InterProiView protein in InterPro
IPR008405 ApoL
PANTHERiPTHR14096 PTHR14096, 1 hit
PfamiView protein in Pfam
PF05461 ApoL, 1 hit

Sequencei

Sequence statusi: Complete.

B3KTP4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNQAERESE AGVGLQRDED DAPLCEDVEL QDGDLSPEEK IFLREFPRLK
60 70 80 90 100
EDLKGNIDKL RALADDIDKT HKKFTKANMV ATSTAVISGV MSLLGLALAP
110 120 130 140 150
ATGGGSLLLS TAGQGLATAA GVTSIVSGTL ERSKNKEAQA RAEDILPTYD
160 170 180 190 200
QEDREDEEEK ADYVTAAGKI IYNLRNTLKY AKKNVRAFWK LRANPRLANA
210 220 230 240 250
TKRLLTTGQV SSRSRVQVQK AFAGTTLAMT KNARVLGGVM SAFSLGYDLA
260 270 280 290 300
TLSKEWKHLK EGARTKFAEE LRAKALELER KLTELTQLYK SLQQKVRSRA
310 320 330 340
RGVGKDLTGT CETEAYWKEL REHVWMWLWL CVCLCVCVYV QFT
Length:343
Mass (Da):38,128
Last modified:September 2, 2008 - v1
Checksum:i9101D15ABAE71CDE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ177991 Genomic DNA Translation: ACN51253.1
AK095881 mRNA Translation: BAG53156.1
CH471095 Genomic DNA Translation: EAW60069.1
RefSeqiNP_085144.1, NM_030641.3
XP_011528694.1, XM_011530392.2
UniGeneiHs.257352

Genome annotation databases

GeneIDi80830
KEGGihsa:80830

Similar proteinsi

Entry informationi

Entry nameiB3KTP4_HUMAN
AccessioniPrimary (citable) accession number: B3KTP4
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: May 23, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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