B3KTL4 (B3KTL4_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA FLJ38453 fis, clone FEBRA2019663, highly similar to Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 42 (DDX42), transcript variant 2, mRNA EMBL BAG53126.1
Organism	Homo sapiens (Human) EMBL BAG53126.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	625 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the DEAD box helicase family. RuleBase RU000492

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Helicase RuleBase RU000492 Hydrolase
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATP-dependent helicase activity Inferred from electronic annotation. Source: InterPro nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B3KTL4 [UniParc]. Last modified September 2, 2008. Version 1. Checksum: 32D7254226D4F592	FASTA	625	68,001
	10 20 30 40 50 60 MHQIRKSEYT QPTPIQCQGV PVALSGRDMI GIAKTGSGKT AAFIWPMLIH IMDQKELEPG 70 80 90 100 110 120 DGPIAVIVCP TRELCQQIHA ECKRFGKAYN LRSVAVYGGG SMWEQAKALQ EGAEIVVCTP 130 140 150 160 170 180 GRLIDHVKKK ATNLQRVSYL VFDEADRMFD MGFEYQVRSI ASHVRPDRQT LLFSATFRKK 190 200 210 220 230 240 IEKLARDILI DPIRVVQGDI GEANEDVTQI VEILHSGPSK WNWLTRRLVE FTSSGSVLLF 250 260 270 280 290 300 VTKKANAEEL ANNLKQEGHN LGLLHGDMDQ SERNKVISDF KKKDIPVLVA TDVAARGLDI 310 320 330 340 350 360 PSIKTVINYD VARDIDTLLT PKDSNFAGDL VRNLEGANQH VSKELLDLAM QNAWFRKSRF 370 380 390 400 410 420 KGGKGKKLNI GGGGLGYRER PGLGSENMDR GNNNVMSNYE AYKPSTGAMG DRLTAMKAAF 430 440 450 460 470 480 QSQYKSHFVA ASLSNQKAGS SAAGASGWTS AGSLNSVPTN SAQQGHNSPD SPVTSAAKGI 490 500 510 520 530 540 PGFGNTGNIS GAPVTYPSAG AQGVNNTASG NNSREGTGGS NGKRERYTEN RGSSRHSHGE 550 560 570 580 590 600 TGNRHSDSPR HGDGGRHGDG YRHPESSSRH TDGHRHGENR HGGSAGRHGE NRGANDGRNG 610 620 ESRKEAFNRE SKMEPPKRKK SRWDS

References

[1]

"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAG53126.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK095772 mRNA. Translation: BAG53126.1.
IPI	IPI01011129.
UniGene	Hs.702010.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B3KTL4.
Proteomic databases
PRIDE	B3KTL4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG081425.
Gene expression databases
ArrayExpress	B3KTL4.
Bgee	B3KTL4.
Family and domain databases
InterPro	IPR011545. DNA/RNA_helicase_DEAD/DEAH_N. IPR014001. Helicase_ATP-bd. IPR001650. Helicase_C. IPR000629. RNA-helicase_DEAD-box_CS. IPR014014. RNA_helicase_DEAD_Q_motif. [Graphical view]
Pfam	PF00270. DEAD. 1 hit. PF00271. Helicase_C. 1 hit. [Graphical view]
SMART	SM00487. DEXDc. 1 hit. SM00490. HELICc. 1 hit. [Graphical view]
PROSITE	PS00039. DEAD_ATP_HELICASE. 1 hit. PS51192. HELICASE_ATP_BIND_1. 1 hit. PS51194. HELICASE_CTER. 1 hit. PS51195. Q_MOTIF. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35469926.

Entry information

Entry name

B3KTL4_HUMAN

Accession

Primary (citable) accession number: B3KTL4

Entry history

Integrated into UniProtKB/TrEMBL:	September 2, 2008
Last sequence update:	September 2, 2008
Last modified:	April 3, 2013
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.