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Protein
Submitted name:

Huntingtin interacting protein 2, isoform CRA_a

Gene

HIP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Huntingtin interacting protein 2, isoform CRA_aImported
Submitted name:
cDNA FLJ36214 fis, clone THYMU2000672, highly similar to Ubiquitin-conjugating enzyme E2-25 kDa (EC 6.3.2.19)Imported
Gene namesi
Name:HIP2Imported
ORF Names:hCG_38552Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_501010524118 – 97Sequence analysisAdd BLAST80

Proteomic databases

PeptideAtlasiB3KSH4

Interactioni

Protein-protein interaction databases

IntActiB3KSH4 40 interactors.

Structurei

3D structure databases

SMRiB3KSH4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 40UBIQUITIN_CONJUGAT_2InterPro annotationAdd BLAST40
Domaini57 – 97UBAInterPro annotationAdd BLAST41

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0418 Eukaryota
COG5078 LUCA
HOGENOMiHOG000233455
HOVERGENiHBG086132

Family and domain databases

Gene3Di3.10.110.101 hit
InterProiView protein in InterPro
IPR015940 UBA
IPR009060 UBA-like_sf
IPR000608 UBQ-conjugat_E2
IPR016135 UBQ-conjugating_enzyme/RWD
PfamiView protein in Pfam
PF00627 UBA, 1 hit
PF00179 UQ_con, 1 hit
SMARTiView protein in SMART
SM00165 UBA, 1 hit
SUPFAMiSSF46934 SSF46934, 1 hit
SSF54495 SSF54495, 1 hit
PROSITEiView protein in PROSITE
PS50030 UBA, 1 hit
PS50127 UBIQUITIN_CONJUGAT_2, 1 hit

Sequencei

Sequence statusi: Complete.

B3KSH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLRTVLLSL QALLAAAEPD DPQDAVVANQ YKQNPEMFKQ TARLWAHVYA
60 70 80 90
GAPVSSPEYT KKIENLCAMG FDRNAVIVAL SSKSWDVETA TELLLSN
Length:97
Mass (Da):10,667
Last modified:September 2, 2008 - v1
Checksum:iC6B08374B5889D0C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK093533 mRNA Translation: BAG52736.1
CH471069 Genomic DNA Translation: EAW92946.1
CH471069 Genomic DNA Translation: EAW92947.1
RefSeqiNP_001299576.1, NM_001312647.1
NP_001299577.1, NM_001312648.1
UniGeneiHs.50308

Genome annotation databases

GeneIDi3093

Similar proteinsi

Entry informationi

Entry nameiB3KSH4_HUMAN
AccessioniPrimary (citable) accession number: B3KSH4
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: February 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.