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Protein
Submitted name:

Huntingtin interacting protein 2, isoform CRA_a

Gene

HIP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Huntingtin interacting protein 2, isoform CRA_aImported
Submitted name:
cDNA FLJ36214 fis, clone THYMU2000672, highly similar to Ubiquitin-conjugating enzyme E2-25 kDa (EC 6.3.2.19)Imported
Gene namesi
Name:HIP2Imported
ORF Names:hCG_38552Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_500764020418 – 97Sequence analysisAdd BLAST80

Proteomic databases

PeptideAtlasiB3KSH4.
PRIDEiB3KSH4.

Expressioni

Gene expression databases

BgeeiENSG00000078140.

Interactioni

Protein-protein interaction databases

IntActiB3KSH4. 40 interactors.
STRINGi9606.ENSP00000261427.

Structurei

3D structure databases

ProteinModelPortaliB3KSH4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 40UBIQUITIN_CONJUGAT_2InterPro annotationAdd BLAST40
Domaini57 – 97UBAInterPro annotationAdd BLAST41

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0418. Eukaryota.
COG5078. LUCA.
HOGENOMiHOG000233455.
HOVERGENiHBG086132.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR015940. UBA.
IPR009060. UBA-like.
IPR000608. UBQ-conjugat_E2.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00627. UBA. 1 hit.
PF00179. UQ_con. 1 hit.
[Graphical view]
SMARTiSM00165. UBA. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54495. SSF54495. 1 hit.
PROSITEiPS50030. UBA. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3KSH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLRTVLLSL QALLAAAEPD DPQDAVVANQ YKQNPEMFKQ TARLWAHVYA
60 70 80 90
GAPVSSPEYT KKIENLCAMG FDRNAVIVAL SSKSWDVETA TELLLSN
Length:97
Mass (Da):10,667
Last modified:September 2, 2008 - v1
Checksum:iC6B08374B5889D0C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK093533 mRNA. Translation: BAG52736.1.
CH471069 Genomic DNA. Translation: EAW92946.1.
CH471069 Genomic DNA. Translation: EAW92947.1.
RefSeqiNP_001299576.1. NM_001312647.1.
NP_001299577.1. NM_001312648.1.
UniGeneiHs.50308.

Genome annotation databases

GeneIDi3093.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK093533 mRNA. Translation: BAG52736.1.
CH471069 Genomic DNA. Translation: EAW92946.1.
CH471069 Genomic DNA. Translation: EAW92947.1.
RefSeqiNP_001299576.1. NM_001312647.1.
NP_001299577.1. NM_001312648.1.
UniGeneiHs.50308.

3D structure databases

ProteinModelPortaliB3KSH4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiB3KSH4. 40 interactors.
STRINGi9606.ENSP00000261427.

Proteomic databases

PeptideAtlasiB3KSH4.
PRIDEiB3KSH4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3093.

Organism-specific databases

CTDi3093.

Phylogenomic databases

eggNOGiKOG0418. Eukaryota.
COG5078. LUCA.
HOGENOMiHOG000233455.
HOVERGENiHBG086132.

Miscellaneous databases

ChiTaRSiUBE2K. human.
GenomeRNAii3093.

Gene expression databases

BgeeiENSG00000078140.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR015940. UBA.
IPR009060. UBA-like.
IPR000608. UBQ-conjugat_E2.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00627. UBA. 1 hit.
PF00179. UQ_con. 1 hit.
[Graphical view]
SMARTiSM00165. UBA. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54495. SSF54495. 1 hit.
PROSITEiPS50030. UBA. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB3KSH4_HUMAN
AccessioniPrimary (citable) accession number: B3KSH4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: November 2, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.