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Protein
Submitted name:

Mitogen-activated protein kinase kinase 2, isoform CRA_d

Gene

MAP2K2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Mitogen-activated protein kinase kinase 2, isoform CRA_dImported
Submitted name:
cDNA FLJ35806 fis, clone TESTI2005987, highly similar to Dual specificity mitogen-activated protein kinase kinase 2 (EC 2.7.12.2)Imported
Gene namesi
Name:MAP2K2Imported
ORF Names:hCG_23544Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PeptideAtlasiB3KS97.
PRIDEiB3KS97.

Expressioni

Gene expression databases

BgeeiENSG00000126934.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000262948.

Structurei

3D structure databases

ProteinModelPortaliB3KS97.
SMRiB3KS97.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 179Protein kinaseInterPro annotationAdd BLAST179

Phylogenomic databases

eggNOGiKOG0581. Eukaryota.
ENOG410XQ5A. LUCA.
HOGENOMiHOG000234206.
HOVERGENiHBG108518.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3KS97-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHRDVKPSNI LVNSRGEIKL CDFGVSGQLI DSMANSFVGT RSYMAPERLQ
60 70 80 90 100
GTHYSVQSDI WSMGLSLVEL AVGRYPIPPP DAKELEAIFG RPVVDGEEGE
110 120 130 140 150
PHSISPRPRP PGRPVSGHGM DSRPAMAIFE LLDYIVNEPP PKLPNGVFTP
160 170 180 190 200
DFQEFVNKCL IKNPAERADL KMLTNHTFIK RSEVEEVDFA GWLCKTLRLN
210
QPGTPTRTAV
Length:210
Mass (Da):23,294
Last modified:September 2, 2008 - v1
Checksum:i8430ED6D9BE7731A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK093125 mRNA. Translation: BAG52659.1.
CH471139 Genomic DNA. Translation: EAW69265.1.
UniGeneiHs.465627.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK093125 mRNA. Translation: BAG52659.1.
CH471139 Genomic DNA. Translation: EAW69265.1.
UniGeneiHs.465627.

3D structure databases

ProteinModelPortaliB3KS97.
SMRiB3KS97.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000262948.

Proteomic databases

PeptideAtlasiB3KS97.
PRIDEiB3KS97.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

CTDi5605.

Phylogenomic databases

eggNOGiKOG0581. Eukaryota.
ENOG410XQ5A. LUCA.
HOGENOMiHOG000234206.
HOVERGENiHBG108518.

Miscellaneous databases

ChiTaRSiMAP2K2. human.
GenomeRNAii5605.

Gene expression databases

BgeeiENSG00000126934.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB3KS97_HUMAN
AccessioniPrimary (citable) accession number: B3KS97
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: November 2, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.