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Protein
Submitted name:

Zinc finger protein with KRAB and SCAN domains 1

Gene

ZKSCAN1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc finger protein with KRAB and SCAN domains 1Imported
Submitted name:
cDNA FLJ34152 fis, clone FCBBF3012901, highly similar to Zinc finger with KRAB and SCAN domain-containing protein 1Imported
Gene namesi
Name:ZKSCAN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

HGNCiHGNC:13101. ZKSCAN1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PeptideAtlasiB3KRF7.

Expressioni

Gene expression databases

BgeeiENSG00000106261.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000323148.

Structurei

3D structure databases

SMRiB3KRF7. Positions 129-331.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 8774KRABInterPro annotationAdd
BLAST
Domaini164 – 19128C2H2-typeInterPro annotationAdd
BLAST
Domaini192 – 21928C2H2-typeInterPro annotationAdd
BLAST
Domaini220 – 24728C2H2-typeInterPro annotationAdd
BLAST
Domaini248 – 27528C2H2-typeInterPro annotationAdd
BLAST
Domaini276 – 30328C2H2-typeInterPro annotationAdd
BLAST
Domaini304 – 33128C2H2-typeInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains KRAB domain.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00760000118881.
HOVERGENiHBG018163.

Family and domain databases

CDDicd07765. KRAB_A-box. 1 hit.
Gene3Di3.30.160.60. 6 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 3 hits.
PF13912. zf-C2H2_6. 1 hit.
PF13465. zf-H2C2_2. 1 hit.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 6 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3KRF7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASALFTADS QAMVKIEDMA VSLILEEWGC QNLARRNLSR DNRQENYGSA
60 70 80 90 100
FPQGGENRNE NEESTSKAET SEDSASRGET TGRSQKEFGE KRDQEGKTGE
110 120 130 140 150
RQQKNPEEKT RKEKRDSGPA IGKDKKTITG ERGPREKGKG LGRSFSLSSN
160 170 180 190 200
FTTPEEVPTG TKSHRCDECG KCFTRSSSLI RHKIIHTGEK PYECSECGKA
210 220 230 240 250
FSLNSNLVLH QRIHTGEKPH ECNECGKAFS HSSNLILHQR IHSGEKPYEC
260 270 280 290 300
NECGKAFSQS SDLTKHQRIH TGEKPYECSE CGKAFNRNSY LILHRRIHTR
310 320 330 340 350
EKPYKCTKCG KAFTRSSTLT LHHRIHARER ASEYSPASLD AFGAFLKSCV
Length:350
Mass (Da):39,324
Last modified:September 2, 2008 - v1
Checksum:i571E460A2C8FC961
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004522 Genomic DNA. No translation available.
AC093619 Genomic DNA. No translation available.
AK091471 mRNA. Translation: BAG52369.1.
RefSeqiNP_001273984.1. NM_001287055.1.
UniGeneiHs.615360.
Hs.633338.
Hs.743424.

Genome annotation databases

EnsembliENST00000535170; ENSP00000443508; ENSG00000106261.
GeneIDi7586.
UCSCiuc003usm.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004522 Genomic DNA. No translation available.
AC093619 Genomic DNA. No translation available.
AK091471 mRNA. Translation: BAG52369.1.
RefSeqiNP_001273984.1. NM_001287055.1.
UniGeneiHs.615360.
Hs.633338.
Hs.743424.

3D structure databases

SMRiB3KRF7. Positions 129-331.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000323148.

Proteomic databases

PeptideAtlasiB3KRF7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000535170; ENSP00000443508; ENSG00000106261.
GeneIDi7586.
UCSCiuc003usm.3. human.

Organism-specific databases

CTDi7586.
HGNCiHGNC:13101. ZKSCAN1.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00760000118881.
HOVERGENiHBG018163.

Miscellaneous databases

ChiTaRSiZKSCAN1. human.
GenomeRNAii7586.

Gene expression databases

BgeeiENSG00000106261.

Family and domain databases

CDDicd07765. KRAB_A-box. 1 hit.
Gene3Di3.30.160.60. 6 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 3 hits.
PF13912. zf-C2H2_6. 1 hit.
PF13465. zf-H2C2_2. 1 hit.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 6 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 6 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB3KRF7_HUMAN
AccessioniPrimary (citable) accession number: B3KRF7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: September 7, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.