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Protein
Submitted name:

Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, isoform CRA_a

Gene

IKBKB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionKinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, isoform CRA_aImported
Submitted name:
cDNA FLJ33978 fis, clone DFNES2004354, highly similar to Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10)Imported
Gene namesi
Name:IKBKBImported
ORF Names:hCG_17395Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

PTM / Processingi

Proteomic databases

MaxQBiB3KRB7
PeptideAtlasiB3KRB7
PRIDEiB3KRB7

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini84 – 161Ubiquitin-likeInterPro annotationAdd BLAST78

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili337 – 357Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4250 Eukaryota
ENOG410XRMU LUCA
HOVERGENiHBG018241

Family and domain databases

InterProiView protein in InterPro
IPR022007 IKKbetaNEMObind
IPR029071 Ubiquitin-like_domsf
IPR000626 Ubiquitin_dom
PfamiView protein in Pfam
PF12179 IKKbetaNEMObind, 1 hit
SMARTiView protein in SMART
SM01239 IKKbetaNEMObind, 1 hit
SUPFAMiSSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50053 UBIQUITIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

B3KRB7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSDGTIRHS KVRQKSEVDI VVSEDLNGTV KFSSSLPYPN NLNSVLAERL
60 70 80 90 100
EKWLQLMLMW HPRQRGTDPT YGPNGCFKAL DDILNLKLVH ILNMVTGTIH
110 120 130 140 150
TYPVTEDESL QSLKARIQQD TGIPEEDQEL LQEAGLALIP DKPATQCISD
160 170 180 190 200
GKLNEGHTLD MDLVFLFDNS KITYETQISP RPQPESVSCI LQEPKRNLAF
210 220 230 240 250
FQLRKVWGQV WHSIQTLKED CNRLQQGQRA AMMNLLRNNS CLSKMKNSMA
260 270 280 290 300
SMSQQLKAKL DFFKTSIQID LEKYSEQTEF GITSDKLLLA WREMEQAVEL
310 320 330 340 350
CGRENEVKLL VERMMALQTD IVDLQRSPMG RKQGGTLDDL EEQARELYRR
360 370 380 390 400
LREKPRDQRT EGDSQEMVRL LLQAIQSFEK KVRVIYTQLS KTVVCKQKAL
410 420 430 440 450
ELLPKVEEVV SLMNEDEKTV VRLQEKRQKE LWNLLKIACS KVRGPVSGSP
460 470 480 490 500
DSMNASRLSQ PGQLMSQPST ASNSLPEPAK KSEELVAEAH NLCTLLENAI
510 520 530
QDTVREQDQS FTALDWSWLQ TEEEEHSCLE QAS
Length:533
Mass (Da):60,819
Last modified:September 2, 2008 - v1
Checksum:i9B0C9FC78DD358FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK091297 mRNA Translation: BAG52329.1
CH471080 Genomic DNA Translation: EAW63222.1
UniGeneiHs.597664

Similar proteinsi

Entry informationi

Entry nameiB3KRB7_HUMAN
AccessioniPrimary (citable) accession number: B3KRB7
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: May 23, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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