Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

Gene

PPP2R1A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoformImported
Submitted name:
cDNA FLJ33169 fis, clone ADRGL2000384, highly similar to Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoformImported
Gene namesi
Name:PPP2R1AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000105568.17.
HGNCiHGNC:9302. PPP2R1A.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000105568.

PTM / Processingi

Proteomic databases

MaxQBiB3KQV6.

Expressioni

Gene expression databases

BgeeiENSG00000105568.
ExpressionAtlasiB3KQV6. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati26 – 64HEATPROSITE-ProRule annotationAdd BLAST39
Repeati65 – 103HEATPROSITE-ProRule annotationAdd BLAST39
Repeati104 – 141HEATPROSITE-ProRule annotationAdd BLAST38
Repeati147 – 185HEATPROSITE-ProRule annotationAdd BLAST39
Repeati186 – 224HEATPROSITE-ProRule annotationAdd BLAST39
Repeati225 – 263HEATPROSITE-ProRule annotationAdd BLAST39
Repeati342 – 380HEATPROSITE-ProRule annotationAdd BLAST39
Repeati381 – 410HEATPROSITE-ProRule annotationAdd BLAST30

Phylogenomic databases

eggNOGiKOG0211. Eukaryota.
ENOG410XQVI. LUCA.
GeneTreeiENSGT00730000110944.
HOVERGENiHBG000011.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiView protein in InterPro
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000357. HEAT.
IPR021133. HEAT_type_2.
IPR031090. PP2A_A_meta.
PANTHERiPTHR10648:SF2. PTHR10648:SF2. 1 hit.
PfamiView protein in Pfam
PF02985. HEAT. 3 hits.
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiView protein in PROSITE
PS50077. HEAT_REPEAT. 8 hits.

Sequencei

Sequence statusi: Complete.

B3KQV6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRRAAASKL GEFAKVLELD NVKSEIIPMF SNLASDEQDS VRLLAVEACV
60 70 80 90 100
NIAQLLPQED LEALVMPTLR QAAEDKSWRV RYMVADKFTE LQKAVGPEIT
110 120 130 140 150
KTDLVPAFQN LMKDCEAEVR AAASHKVKEF CENLSADCRE NVIMSQILPC
160 170 180 190 200
IKELVSDANQ HVKSALASVI MGLSPILGKD NTIEHLLPLF LAQLKDECPE
210 220 230 240 250
VRLNIISNLD CVNEVIGIRQ LSQSLLPAIV ELAEDAKWRV RLAIIEYMPL
260 270 280 290 300
LAGQLGVEFF DEKLNSLCMA WLVDHVYAIR EAATSNLKKL VEKFGKEWAH
310 320 330 340 350
ATIIPKVLAM SGDPNYLHRM TTLFCINVLS EVCGQDITTK HMLPTVLRMA
360 370 380 390 400
GDPVANVRFN VAKSLQKIGP ILDNSTLQSE VKPILEKLTQ DQDVDVKYFA
410
QEALTVLSLA
Length:410
Mass (Da):45,604
Last modified:September 2, 2008 - v1
Checksum:i2AF05E07964A193F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010320 Genomic DNA. No translation available.
AK090488 mRNA. Translation: BAG52168.1.
RefSeqiXP_016882418.1. XM_017026929.1.
UniGeneiHs.467192.

Genome annotation databases

EnsembliENST00000462990; ENSP00000470504; ENSG00000105568.
GeneIDi5518.
UCSCiuc002pyq.4. human.

Similar proteinsi

Entry informationi

Entry nameiB3KQV6_HUMAN
AccessioniPrimary (citable) accession number: B3KQV6
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: October 25, 2017
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported