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B3KPF0

- B3KPF0_HUMAN

UniProt

B3KPF0 - B3KPF0_HUMAN

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Protein
Submitted name:

cDNA FLJ31712 fis, clone NT2RI2006445, highly similar to Insulin-like growth factor-binding protein 3

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. positive regulation of insulin-like growth factor receptor signaling pathway Source: Ensembl
  2. positive regulation of MAPK cascade Source: Ensembl
  3. regulation of cell growth Source: Ensembl
  4. regulation of glucose metabolic process Source: Ensembl
  5. type B pancreatic cell proliferation Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ31712 fis, clone NT2RI2006445, highly similar to Insulin-like growth factor-binding protein 3Imported
Submitted name:
cDNA FLJ34387 fis, clone HCHON1000191, highly similar to Insulin-like growth factor-binding protein 3Imported
Submitted name:
cDNA FLJ38550 fis, clone HCHON2002123, highly similar to Insulin-like growth factor-binding protein 3Imported
Submitted name:
cDNA PSEC0177 fis, clone OVARC1000287, highly similar to Insulin-like growth factor-binding protein 3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: Ensembl
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA29705.

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000253012.
HOVERGENiHBG101822.
KOiK10138.

Family and domain databases

Gene3Di4.10.800.10. 1 hit.
InterProiIPR012211. IGFBP-3.
IPR009168. IGFBP1-6.
IPR000716. Thyroglobulin_1.
[Graphical view]
PANTHERiPTHR11551. PTHR11551. 1 hit.
PTHR11551:SF3. PTHR11551:SF3. 1 hit.
PfamiPF00086. Thyroglobulin_1. 1 hit.
[Graphical view]
SMARTiSM00211. TY. 1 hit.
[Graphical view]
SUPFAMiSSF57610. SSF57610. 1 hit.
PROSITEiPS00484. THYROGLOBULIN_1_1. 1 hit.
PS51162. THYROGLOBULIN_1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3KPF0-1 [UniParc]FASTAAdd to Basket

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MEDTLNHLKF LNVLSPRGVH IPNCDKKGFY KKKQCRPSKG RKRGFCWCVD   50
KYGQPLPGYT TKGKEDVHCY SMQSK 75
Length:75
Mass (Da):8,708
Last modified:September 2, 2008 - v1
Checksum:i8BBDFD878FFD01CF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK056274 mRNA. Translation: BAG51662.1.
AK075483 mRNA. Translation: BAG52153.1.
AK091706 mRNA. Translation: BAG52402.1.
AK095869 mRNA. Translation: BAG53151.1.
RefSeqiNP_000589.2. NM_000598.4.
UniGeneiHs.450230.

Genome annotation databases

GeneIDi3486.
KEGGihsa:3486.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK056274 mRNA. Translation: BAG51662.1 .
AK075483 mRNA. Translation: BAG52153.1 .
AK091706 mRNA. Translation: BAG52402.1 .
AK095869 mRNA. Translation: BAG53151.1 .
RefSeqi NP_000589.2. NM_000598.4.
UniGenei Hs.450230.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

DNASUi 3486.
Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3486.
KEGGi hsa:3486.

Organism-specific databases

CTDi 3486.
PharmGKBi PA29705.

Phylogenomic databases

HOGENOMi HOG000253012.
HOVERGENi HBG101822.
KOi K10138.

Miscellaneous databases

GenomeRNAii 3486.
NextBioi 13708.

Family and domain databases

Gene3Di 4.10.800.10. 1 hit.
InterProi IPR012211. IGFBP-3.
IPR009168. IGFBP1-6.
IPR000716. Thyroglobulin_1.
[Graphical view ]
PANTHERi PTHR11551. PTHR11551. 1 hit.
PTHR11551:SF3. PTHR11551:SF3. 1 hit.
Pfami PF00086. Thyroglobulin_1. 1 hit.
[Graphical view ]
SMARTi SM00211. TY. 1 hit.
[Graphical view ]
SUPFAMi SSF57610. SSF57610. 1 hit.
PROSITEi PS00484. THYROGLOBULIN_1_1. 1 hit.
PS51162. THYROGLOBULIN_1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries."
    Otsuki T., Ota T., Nishikawa T., Hayashi K., Suzuki Y., Yamamoto J., Wakamatsu A., Kimura K., Sakamoto K., Hatano N., Kawai Y., Ishii S., Saito K., Kojima S., Sugiyama T., Ono T., Okano K., Yoshikawa Y.
    , Aotsuka S., Sasaki N., Hattori A., Okumura K., Nagai K., Sugano S., Isogai T.
    DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: OvaryImported.

Entry informationi

Entry nameiB3KPF0_HUMAN
AccessioniPrimary (citable) accession number: B3KPF0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: September 3, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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