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Protein
Submitted name:

cDNA FLJ31217 fis, clone KIDNE2004095, highly similar to RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiB3KP61.

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ31217 fis, clone KIDNE2004095, highly similar to RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

MaxQBiB3KP61.
PaxDbiB3KP61.
PeptideAtlasiB3KP61.
PRIDEiB3KP61.

Expressioni

Gene expression databases

BgeeiENSG00000105221.

Structurei

3D structure databases

ProteinModelPortaliB3KP61.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 310Protein kinaseInterPro annotationAdd BLAST258
Domaini311 – 382AGC-kinase C-terminalInterPro annotationAdd BLAST72

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0598. Eukaryota.
ENOG410XNPH. LUCA.
HOVERGENiHBG108317.

Family and domain databases

CDDicd05595. STKc_PKB_beta. 1 hit.
InterProiView protein in InterPro
IPR000961. AGC-kinase_C.
IPR034677. Akt2.
IPR011009. Kinase-like_dom.
IPR017892. Pkinase_C.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
PF00433. Pkinase_C. 1 hit.
SMARTiView protein in SMART
SM00133. S_TK_X. 1 hit.
SM00220. S_TKc. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS51285. AGC_KINASE_CTER. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.

Sequencei

Sequence statusi: Complete.

B3KP61-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRAIQMVANS LKQRAPGEDP MDYKCGSPSD SSTTEEMEVA VSKARAKVTM
60 70 80 90 100
NDFDYLKLLG KGTFGKVILV REKATGRYYA MKILRKEVII AKDEVAHTVT
110 120 130 140 150
ESRVLQNTRH PFLTALKYAF QTHDRLCFVM EYANGGELFF HLSRERVFTE
160 170 180 190 200
ERARFYGAEI VSALEYLHSR DVVYRDIKLE NLMLDKDGHI KITDFGLCKE
210 220 230 240 250
GISDGATMKT FCGTPEYLAP EVLEDNDYGR AVDWWGLGVV MYEMMCGRLP
260 270 280 290 300
FYNQDHERLF ELILMEEIRF PRTLSPEAKS LLAGLLKKDP KQRLGGGPSD
310 320 330 340 350
AKEVMEHRFF LSINWQDVVQ KKLLPPFKPQ VTSEVDTRYF DDEFTAQSIT
360 370 380
ITPPDRYDSL GLLELDQRTH FPQFSYSASI RE
Length:382
Mass (Da):43,916
Last modified:September 2, 2008 - v1
Checksum:iB859F9313B1874C1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK055779 mRNA. Translation: BAG51573.1.
UniGeneiHs.631535.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiB3KP61_HUMAN
AccessioniPrimary (citable) accession number: B3KP61
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: July 5, 2017
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.