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Protein
Submitted name:

cDNA FLJ10827 fis, clone NT2RP4001117, highly similar to Protein transport protein Sec61 subunit alpha isoform 1

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ10827 fis, clone NT2RP4001117, highly similar to Protein transport protein Sec61 subunit alpha isoform 1Imported
Submitted name:
cDNA FLJ14546 fis, clone NT2RM2001613, highly similar to Protein transport protein Sec61 subunit alpha isoform 1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei53 – 74HelicalSequence analysisAdd BLAST22
Transmembranei107 – 125HelicalSequence analysisAdd BLAST19
Transmembranei131 – 152HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134901772.

Family & Domainsi

Sequence similaritiesi

Belongs to the SecY/SEC61-alpha family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1373. Eukaryota.
COG0201. LUCA.
HOGENOMiHOG000231249.
HOVERGENiHBG078361.
KOiK10956.

Family and domain databases

InterProiView protein in InterPro
IPR002208. SecY/SEC61-alpha.
IPR023201. SecY_su_dom.
PANTHERiPTHR10906. PTHR10906. 1 hit.
PfamiView protein in Pfam
PF00344. SecY. 1 hit.
SUPFAMiSSF103491. SSF103491. 1 hit.

Sequencei

Sequence statusi: Complete.

B3KME8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSARFSGNL LVSLLGTWSD TSSGGPARAY PVGGLCYYLS PPESFGSVLE
60 70 80 90 100
DPVHAVVYIV FMLGSCAFFS KTWIEVSGSS AKDVAKQLKE QQMVMRGHRE
110 120 130 140 150
TSMVHELNRY IPTAAAFGGL CIGALSVLAD FLGAIGSGTG ILLAVTIIYQ
160 170
YFEIFVKEQS EVGSMGALLF
Length:170
Mass (Da):18,176
Last modified:September 2, 2008 - v1
Checksum:iA9592F3C68619F26
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001689 mRNA. Translation: BAG50960.1.
AK027452 mRNA. Translation: BAG51323.1.
RefSeqiNP_037468.1. NM_013336.3.
UniGeneiHs.518236.

Genome annotation databases

GeneIDi29927.
KEGGihsa:29927.

Similar proteinsi

Entry informationi

Entry nameiB3KME8_HUMAN
AccessioniPrimary (citable) accession number: B3KME8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: August 30, 2017
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.