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Protein
Submitted name:

cDNA FLJ10827 fis, clone NT2RP4001117, highly similar to Protein transport protein Sec61 subunit alpha isoform 1

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ10827 fis, clone NT2RP4001117, highly similar to Protein transport protein Sec61 subunit alpha isoform 1Imported
Submitted name:
cDNA FLJ14546 fis, clone NT2RM2001613, highly similar to Protein transport protein Sec61 subunit alpha isoform 1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei53 – 7422HelicalSequence analysisAdd
BLAST
Transmembranei107 – 12519HelicalSequence analysisAdd
BLAST
Transmembranei131 – 15222HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134901772.

PTM / Processingi

Proteomic databases

PaxDbiB3KME8.

Expressioni

Gene expression databases

BgeeiB3KME8.
GenevisibleiB3KME8. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000243253.

Structurei

3D structure databases

ProteinModelPortaliB3KME8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SecY/SEC61-alpha family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1373. Eukaryota.
COG0201. LUCA.
HOGENOMiHOG000231249.
HOVERGENiHBG078361.
KOiK10956.

Family and domain databases

Gene3Di1.10.3370.10. 1 hit.
InterProiIPR002208. SecY/SEC61-alpha.
IPR023201. SecY_su_dom.
[Graphical view]
PANTHERiPTHR10906. PTHR10906. 1 hit.
PfamiPF00344. SecY. 1 hit.
[Graphical view]
SUPFAMiSSF103491. SSF103491. 1 hit.

Sequencei

Sequence statusi: Complete.

B3KME8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSARFSGNL LVSLLGTWSD TSSGGPARAY PVGGLCYYLS PPESFGSVLE
60 70 80 90 100
DPVHAVVYIV FMLGSCAFFS KTWIEVSGSS AKDVAKQLKE QQMVMRGHRE
110 120 130 140 150
TSMVHELNRY IPTAAAFGGL CIGALSVLAD FLGAIGSGTG ILLAVTIIYQ
160 170
YFEIFVKEQS EVGSMGALLF
Length:170
Mass (Da):18,176
Last modified:September 2, 2008 - v1
Checksum:iA9592F3C68619F26
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001689 mRNA. Translation: BAG50960.1.
AK027452 mRNA. Translation: BAG51323.1.
RefSeqiNP_037468.1. NM_013336.3.
UniGeneiHs.518236.

Genome annotation databases

GeneIDi29927.
KEGGihsa:29927.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001689 mRNA. Translation: BAG50960.1.
AK027452 mRNA. Translation: BAG51323.1.
RefSeqiNP_037468.1. NM_013336.3.
UniGeneiHs.518236.

3D structure databases

ProteinModelPortaliB3KME8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000243253.

Proteomic databases

PaxDbiB3KME8.

Protocols and materials databases

DNASUi29927.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi29927.
KEGGihsa:29927.

Organism-specific databases

CTDi29927.
PharmGKBiPA134901772.

Phylogenomic databases

eggNOGiKOG1373. Eukaryota.
COG0201. LUCA.
HOGENOMiHOG000231249.
HOVERGENiHBG078361.
KOiK10956.

Miscellaneous databases

GenomeRNAii29927.
NextBioi52551.

Gene expression databases

BgeeiB3KME8.
GenevisibleiB3KME8. HS.

Family and domain databases

Gene3Di1.10.3370.10. 1 hit.
InterProiIPR002208. SecY/SEC61-alpha.
IPR023201. SecY_su_dom.
[Graphical view]
PANTHERiPTHR10906. PTHR10906. 1 hit.
PfamiPF00344. SecY. 1 hit.
[Graphical view]
SUPFAMiSSF103491. SSF103491. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiB3KME8_HUMAN
AccessioniPrimary (citable) accession number: B3KME8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: March 16, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.