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Protein
Submitted name:

Nucleolin, isoform CRA_c

Gene

NCL

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Nucleolin, isoform CRA_cImported
Submitted name:
cDNA FLJ10452 fis, clone NT2RP1000966, highly similar to NUCLEOLINImported
Gene namesi
Name:NCLImported
ORF Names:hCG_33980Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31469.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini133 – 209RRMInterPro annotationAdd BLAST77
Domaini219 – 292RRMInterPro annotationAdd BLAST74
Domaini312 – 386RRMInterPro annotationAdd BLAST75
Domaini398 – 473RRMInterPro annotationAdd BLAST76

Phylogenomic databases

eggNOGiENOG410IRS7. Eukaryota.
ENOG410XSFV. LUCA.
HOVERGENiHBG002295.
KOiK11294.

Family and domain databases

CDDicd12403. RRM1_NCL. 1 hit.
cd12404. RRM2_NCL. 1 hit.
cd12405. RRM3_NCL. 1 hit.
cd12406. RRM4_NCL. 1 hit.
InterProiView protein in InterPro
IPR034230. Nucleolin_RRM1.
IPR034233. Nucleolin_RRM2.
IPR034234. Nucleolin_RRM3.
IPR034235. Nucleolin_RRM4.
IPR000504. RRM_dom.
IPR003954. RRM_dom_euk.
PfamiView protein in Pfam
PF00076. RRM_1. 4 hits.
SMARTiView protein in SMART
SM00360. RRM. 4 hits.
SM00361. RRM_1. 2 hits.
SUPFAMiSSF54928. SSF54928. 3 hits.
PROSITEiView protein in PROSITE
PS50102. RRM. 4 hits.

Sequencei

Sequence statusi: Complete.

B3KM80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKAAAAAPAS EDEDDEDDED DEDDDDDEED DSEEEAMETT PAKGKKAAKV
60 70 80 90 100
VPVKAKNVAE DEDEEEDDED EDDDDDEDDE DDDDEDDEEE EEEEEEEPVK
110 120 130 140 150
EAPGKRKKEM AKQKAAPEAK KQKVEGTEPT TAFNLFVGNL NFNKSAPELK
160 170 180 190 200
TGISDVFAKN DLAVVDVRIG MTRKFGYVDF ESAEDLEKAL ELTGLKVFGN
210 220 230 240 250
EIKLEKPKGK DSKKERDART LLAKNLPYKV TQDELKEVFE DAAEIRLVSK
260 270 280 290 300
DGKSKGIAYI EFKTEADAEK TFEEKQGTEI DGRSISLYYT GEKGQNQDYR
310 320 330 340 350
GGKNSTWSGE SKTLVLSNLS YSATEETLQE VFEKATFIKV PQNQNGKSKG
360 370 380 390 400
YAFIEFASFE DAKEALNSCN KREIEGRAIR LELQGPRGSP NARSQPSKTL
410 420 430 440 450
FVKGLSEDTT EETLKESFDG SVRARIVTDR ETGSSKGFGF VDFNSEEDAK
460 470 480 490 500
AAKEAMEDGE IDGNKVTLDW AKPKGEGGFG GRGGGRGGFG GRGGGRGGRG
510 520 530
GFGGRGRGGF GGRGGFRGGR GGGGDHKPQG KKTKFE
Length:536
Mass (Da):58,554
Last modified:September 2, 2008 - v1
Checksum:i2230178D72182E45
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001314 mRNA. Translation: BAG50892.1.
CH471063 Genomic DNA. Translation: EAW70962.1.
RefSeqiNP_005372.2. NM_005381.2.
UniGeneiHs.79110.

Genome annotation databases

GeneIDi4691.
KEGGihsa:4691.

Similar proteinsi

Entry informationi

Entry nameiB3KM80_HUMAN
AccessioniPrimary (citable) accession number: B3KM80
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: September 27, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.