Skip Header

Contribute Send feedback
Read comments (?) or add your own

B3J2Z5 (B3J2Z5_BACAN) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
6,7-dimethyl-8-ribityllumazine synthase HAMAP MF_00178
Short name=DMRL synthase HAMAP MF_00178
Short name=Lumazine synthase HAMAP MF_00178
EC=2.5.1.9 HAMAP MF_00178
Alternative name(s):
Riboflavin synthase beta chain HAMAP MF_00178
Gene names
Name:ribH HAMAP MF_00178 EMBL EDV16735.1
ORF Names:BATI_4177 EMBL EDV16735.1
OrganismBacillus anthracis Tsiankovskii-I EMBL EDV16735.1
Taxonomic identifier405536 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length153 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2-butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes the condensation of 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate yielding 6,7-dimethyl-8-lumazine By similarity. HAMAP MF_00178

Catalytic activity

2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine. HAMAP MF_00178 RuleBase RU003795

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 2/2. HAMAP MF_00178 RuleBase RU003795

Sequence similarities

Belongs to the DMRL synthase family. HAMAP MF_00178 RuleBase RU003795

Sequences

Sequence LengthMass (Da)Tools
B3J2Z5 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: AA5391784EA66839

FASTA15316,255
        10         20         30         40         50         60 
MVFEGHLVGT GLKVGVVVGR FNEFITSKLL GGALDGLKRH GVEENDIDVA WVPGAFEIPL 

        70         80         90        100        110        120 
IAKKMANSGK YDAVITLGTV IRGATTHYDY VCNEVAKGVA SLSLQTDIPV IFGVLTTETI 

       130        140        150 
EQAIERAGTK AGNKGYESAV AAIEMAHLSK HWA

« Hide

References

[1]"Genome sequence of Bacillus anthracis Tsiankovskii-I."
Dodson R.J., Durkin A.S., Sutton G.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Tsiankovskii-I EMBL EDV16735.1.
[2]Rosovitz M.J., Rasko D.A., Friedlander A., Ravel J.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Tsiankovskii-I EMBL EDV16735.1.
[3]Dodson R.J., Durkin A.S., Sutton G.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Tsiankovskii-I EMBL EDV16735.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		ABDN02000003 Genomic DNA. Translation: EDV16735.1.

3D structure databases

ProteinModelPortalB3J2Z5.
SMRB3J2Z5. Positions 2-152.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

PATRIC24568570. VBIBacAnt18208_1676.

Phylogenomic databases

OMADYVCNEA.

Family and domain databases

HAMAPMF_00178. Lumazine_synth.
[Tree]
InterProIPR002180. DMRL_synthase.
[Graphical view]
Gene3DG3DSA:3.40.50.960. DMRL_synthase. 1 hit.
PANTHERPTHR21058. DMRL_synthase. 1 hit.
PfamPF00885. DMRL_synthase. 1 hit.
[Graphical view]
SUPFAMSSF52121. DMRL_synthase. 1 hit.
TIGRFAMsTIGR00114. Lumazine-synth. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB3J2Z5_BACAN
AccessionPrimary (citable) accession number: B3J2Z5
Entry history
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info