B3HRR4 (B3HRR4_ECOLX) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Chorismate--pyruvate lyase HAMAP MF_01632
Short name=CL HAMAP MF_01632
Short name=CPL HAMAP MF_01632
EC=4.1.3.40 HAMAP MF_01632

Gene names

Name:	ubiC HAMAP MF_01632 EMBL EDV67316.1
ORF Names:	EcF11_4666 EMBL EDV67316.1

Organism

Escherichia coli F11 EMBL EDV67316.1

Taxonomic identifier

340197 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	165 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity. HAMAP MF_01632 SAAS SAAS007440
Catalytic activity	Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632 SAAS SAAS007440
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632 SAAS SAAS007440
Subunit structure	Monomer By similarity. HAMAP MF_01632
Subcellular location	Cytoplasm By similarity HAMAP MF_01632 SAAS SAAS007440.
Sequence similarities	Belongs to the ubiC family. HAMAP MF_01632

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis HAMAP MF_01632 SAAS SAAS007440
Cellular component	Cytoplasm HAMAP MF_01632 SAAS SAAS007440
Ligand	Pyruvate HAMAP MF_01632 SAAS SAAS007440
Molecular function	Lyase HAMAP MF_01632 SAAS SAAS007440 EMBL EDV67316.1
Gene Ontology (GO)
Biological process	pyruvate biosynthetic process Inferred from electronic annotation. Source: HAMAP ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chorismate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Binding site	35	1	Substrate; via amide nitrogen By similarity HAMAP MF_01632
	Binding site	77	1	Substrate By similarity HAMAP MF_01632
	Binding site	115	1	Substrate; via amide nitrogen By similarity HAMAP MF_01632

Sequences

	Sequence		Length	Mass (Da)
	B3HRR4 [UniParc]. Last modified September 2, 2008. Version 1. Checksum: 7705434B48859FB6	FASTA	165	18,808
	10 20 30 40 50 60 MSHPALTQLR ALRYFTEIPA LEPQLLDWLL LEDSMTKRFE QQGKTVSVTM IREGFVEQNE 70 80 90 100 110 120 IPEELPLLPK ESRYWLREIL LCADGEPWLA GRTVVPVSTL SGPELALQKL GKTPLGRYLF 130 140 150 160 TSSTLTRDFI EIGRDAGLWG RRSRLRLSGK PLLLTELFLP ASPLY

References

[1]	Rasko D.A., Rosovitz M.J., Mobley H.L.T., Myers G.S.A., Seshadri R., Cer R.Z., Jiang L., Ravel J. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: F11 EMBL EDV67316.1.
[2]	Rasko D., Rosovitz M., Myers G., Seshadri R., Cer R., Jiang L., Ravel J., Fricke W.F., Sebastian Y. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: F11 EMBL EDV67316.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAJU02000010 Genomic DNA. Translation: EDV67316.1.
3D structure databases
ProteinModelPortal	B3HRR4.
SMR	B3HRR4. Positions 2-165.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	26551916. VBIEscCol13398_2152.
Family and domain databases
HAMAP	MF_01632. UbiC. [Tree]
InterPro	IPR007440. Chorismate--pyruvate_lyase. [Graphical view]
Pfam	PF04345. Chor_lyase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B3HRR4_ECOLX

Accession

Primary (citable) accession number: B3HRR4

Entry history

Integrated into UniProtKB/TrEMBL:	September 2, 2008
Last sequence update:	September 2, 2008
Last modified:	December 14, 2011
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)