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Protein

Proton pump-interactor 2

Gene

PPI2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May regulate plasma membrane ATPase activity.By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Proton pump-interactor 2
Gene namesi
Name:PPI2
Ordered Locus Names:At3g15340
ORF Names:K7L4.14
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G15340
TAIRilocus:2087115 AT3G15340

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei568 – 588HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004202131 – 589Proton pump-interactor 2Add BLAST589

Proteomic databases

PaxDbiB3H4K7

Expressioni

Tissue specificityi

Expressed in seedlings and flowers.1 Publication

Gene expression databases

ExpressionAtlasiB3H4K7 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi3702.AT3G15340.1

Structurei

3D structure databases

ProteinModelPortaliB3H4K7
SMRiB3H4K7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili205 – 245Sequence analysisAdd BLAST41
Coiled coili431 – 500Sequence analysisAdd BLAST70

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi461 – 494Lys-richAdd BLAST34

Sequence similaritiesi

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410JS4I Eukaryota
ENOG41119YJ LUCA
HOGENOMiHOG000243080
InParanoidiB3H4K7
OMAiQIEHGSI
OrthoDBiEOG093607WL
PhylomeDBiB3H4K7

Family and domain databases

InterProiView protein in InterPro
IPR029669 PPI
PANTHERiPTHR32219:SF2 PTHR32219:SF2, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: B3H4K7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MGAQIILSEG FEVVPPPEMN DLVLFGSNQS VSSCDVSTVT TEDGTVFSGD
60 70 80 90 100
SSPGGATEED FPEEKPFSFY FVKQPAYDDP EIKAKIDEAG HEINRYNKDR
110 120 130 140 150
IVVSNAQESE KAEILSLFGQ MKSLVSKSEG YRVVIEEKKM EFDALHESLR
160 170 180 190 200
NLRCSTSDQL CFSKEELDHL IYIAHYQIEH GSIGFEEEDW VLKETEKADG
210 220 230 240 250
IVLSEDSLAE KEASINRVKS MAVELNEVKK ELDAITWKIN HLSDKVGKSQ
260 270 280 290 300
NNLRVLDVKK AHILEERDRS YERIKMLRIQ RDKGKAAFYQ SLPVMRKARE
310 320 330 340 350
LAASGNVRDL EVFASSEADR FMTQWNDDKA FRDDYVKRIS PSLCERQLNQ
360 370 380 390 400
DGRIKDPEVQ VVWEKKVPVK GGEKVHETNR EDSSSNSSQY GSVITDKRKK
410 420 430 440 450
ETRKKAMDFN RSSAEESDVT DLEFSVYEKP KKEEEEVDEE TLKEREREEQ
460 470 480 490 500
LEKARLAMER KRKLQEKAAA KAAIRAQKEA EKKLKECEKK AKKKAAANSS
510 520 530 540 550
SPSESDHSQE VTKDLEKVRT LAVSGKEKHQ KERSLFPKQR SFRYKHRGRG
560 570 580
TEALPKAILN RRKAHKYWVW GLSSAALAVA LFLVVLLLR
Length:589
Mass (Da):67,324
Last modified:July 22, 2008 - v1
Checksum:i5CB13AF9D7AC2263
GO
Isoform 2 (identifier: B3H4K7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-120: Missing.

Note: Derived from EST data. No experimental confirmation available.
Show »
Length:469
Mass (Da):54,244
Checksum:i92D5504372FAEF1E
GO

Sequence cautioni

The sequence BAB02163 differs from that shown. Reason: Erroneous gene model prediction.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0444231 – 120Missing in isoform 2. CuratedAdd BLAST120

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000413 Genomic DNA Translation: BAB02163.1 Sequence problems.
CP002686 Genomic DNA Translation: AEE75643.1
CP002686 Genomic DNA Translation: AEE75644.1
CP002686 Genomic DNA Translation: ANM64261.1
RefSeqiNP_001118633.1, NM_001125161.1 [B3H4K7-2]
NP_001326301.1, NM_001338153.1 [B3H4K7-1]
NP_188152.3, NM_112397.4 [B3H4K7-1]
UniGeneiAt.50184

Genome annotation databases

EnsemblPlantsiAT3G15340.1; AT3G15340.1; AT3G15340 [B3H4K7-1]
AT3G15340.2; AT3G15340.2; AT3G15340 [B3H4K7-2]
AT3G15340.3; AT3G15340.3; AT3G15340 [B3H4K7-1]
GeneIDi820765
GrameneiAT3G15340.1; AT3G15340.1; AT3G15340 [B3H4K7-1]
AT3G15340.2; AT3G15340.2; AT3G15340 [B3H4K7-2]
AT3G15340.3; AT3G15340.3; AT3G15340 [B3H4K7-1]
KEGGiath:AT3G15340

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiPPI2_ARATH
AccessioniPrimary (citable) accession number: B3H4K7
Secondary accession number(s): B6EUC1, Q9LJR4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2012
Last sequence update: July 22, 2008
Last modified: April 25, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health