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B3H328 (B3H328_ACTP7) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA mismatch repair protein mutL HAMAP MF_00149
Gene names
Name:mutL HAMAP MF_00149
Ordered Locus Names:APP7_2046
OrganismActinobacillus pleuropneumoniae serotype 7 (strain AP76) [Complete proteome] [HAMAP] EMBL ACE62698.1
Taxonomic identifier537457 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length661 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex By similarity. HAMAP MF_00149 SAAS SAAS020667

Sequence similarities

Belongs to the DNA mismatch repair mutL/hexB family. HAMAP MF_00149

Ontologies

Keywords
   Biological processDNA damage
DNA repair HAMAP MF_00149 SAAS SAAS020667
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processmismatch repair

Inferred from electronic annotation. Source: HAMAP

   Molecular functionATP binding

Inferred from electronic annotation. Source: InterPro

mismatched DNA binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
B3H328 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: B568199418B4ACF5

FASTA66174,331
        10         20         30         40         50         60 
MILKKIYLRI KRVETPFSIK TRIFSLEWAL YFYCYSRNSM NKPLIHILPP QLANQIAAGE 

        70         80         90        100        110        120 
VVERPASVVK ELVENSLDAG ANQIQIDIEK GGAQLIRIRD NGCGIGKQDL ALALARHATS 

       130        140        150        160        170        180 
KISSLEDLEM ILSLGFRGEA LASISSVSRL TLTSRPAGQA EAWQAYAQGR EMEVEIQPAS 

       190        200        210        220        230        240 
HPVGTTIEVA NLFFNTPARR KFLRTDKTEF THIDEVVRRI ALAKPNIGFT LTHNGKTVRQ 

       250        260        270        280        290        300 
YRKVQDNSVE QQQRRVAAIC GDDFIQNAIH IDWQHGDLHL HGWIGLPNIS RPQNDLCYSY 

       310        320        330        340        350        360 
VNGRMMRDKT INHAIRQAYE ATDMPEGNYP AFVVFLDIDP SQVDVNVHPA KHEVRFHQGR 

       370        380        390        400        410        420 
LVHDFILQGV QTALQGQAEI DLTHQVNEPL PSYQRNTNRM AAGGNSFLAS QQAVEFTENF 

       430        440        450        460        470        480 
AKPTASHMPN YSPRTSGVSK SAQKWYGELV SQPQNQSDNI QDLIEPKANF APVIFAQEID 

       490        500        510        520        530        540 
EAEPKPTQVV SAAIGHWQPL AIVQNQALLL KAEQQFYLLS LEKLARLRFQ TQLTKGESQA 

       550        560        570        580        590        600 
LLIPLNLSLD EQQTQRWQTL KTPLVELGFA ISEKTWQGQI RLSVTQVPRL LREQNLQQIL 

       610        620        630        640        650        660 
LSLFASQAVD LTEFFAKFAP ILTAYSLAEA VNWLAETEQT AKSELEKLKV AVDFSAFLAR 


C

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References

[1]"Genome and proteome analysis of A. pleuropneumoniae serotype 7."
Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N., Tegetmeyer H., Singh M., Gerlach G.F.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001091 Genomic DNA. Translation: ACE62698.1.
RefSeqYP_001969840.1. NC_010939.1.

3D structure databases

ProteinModelPortalB3H328.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3H328.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6397958.
GenomeReviewsGene locus APP7_2046 in contig CP001091_GR.
KEGGapa:APP7_2046.
PATRIC20757909. VBIActPle116979_2098.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG520262.
OMAEVANLFF.
ProtClustDBPRK00095.

Family and domain databases

HAMAPMF_00149. DNA_mis_repair.
[Tree]
InterProIPR003594. ATPase-like_ATP-bd.
IPR002099. DNA_mismatch_repair.
IPR013507. DNA_mismatch_repair_C.
IPR014762. DNA_mismatch_repair_CS.
IPR020667. DNA_mismatch_repair_MutL.
IPR014763. DNA_mismatch_repair_N.
IPR014790. MutL_C.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view]
Gene3DG3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit.
G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
KOK03572.
PANTHERPTHR10073. DNA_mis_repair. 1 hit.
PfamPF01119. DNA_mis_repair. 1 hit.
PF02518. HATPase_c. 1 hit.
PF08676. MutL_C. 1 hit.
[Graphical view]
SMARTSM00387. HATPase_c. 1 hit.
SM00853. MutL_C. 1 hit.
[Graphical view]
SUPFAMSSF55874. ATP_bd_ATPase. 1 hit.
SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMsTIGR00585. Mutl. 1 hit.
PROSITEPS00058. DNA_MISMATCH_REPAIR_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB3H328_ACTP7
AccessionPrimary (citable) accession number: B3H328
Entry history
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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