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B3H2F9 (PSD_ACTP7) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:APP7_1532
OrganismActinobacillus pleuropneumoniae serotype 7 (strain AP76) [Complete proteome] [HAMAP]
Taxonomic identifier537457 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length296 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00662

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 262262Phosphatidylserine decarboxylase beta chain By similarity
PRO_1000131328
Chain263 – 29634Phosphatidylserine decarboxylase alpha chain By similarity
PRO_1000131329

Sites

Site262 – 2632Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2631Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
B3H2F9 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: E0B5079993FA36D5

FASTA29633,654
        10         20         30         40         50         60 
MSLKPYATPT YWQRVKVAFQ YIFPQLPVTR LAGWLAEQKW GAVTHFIIRT FAKQYKVNLS 

        70         80         90        100        110        120 
EAQKSNASDY ATFNEFFIRP LKENARPINQ DAQALCLPAD GKVSESGKIE DDRLLQAKGH 

       130        140        150        160        170        180 
FFTLETLLAN DQEMANKFKD GHFITTYLSP RDYHRVHMPC DATLRKMIYV PGELFSVNPF 

       190        200        210        220        230        240 
LAEHVPNLFA RNERVICEFE TEFGPMVQIL VGATITASMS TVWAGIINPP RTKEVVEYHY 

       250        260        270        280        290 
ETSGETAVHL KKGQEMGAFR LGSTVINLFP KDSVEFEAHL QAGVETRMGE RLAKIK

« Hide

References

[1]"Genome and proteome analysis of A. pleuropneumoniae serotype 7."
Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N., Tegetmeyer H., Singh M., Gerlach G.F.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AP76.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001091 Genomic DNA. Translation: ACE62184.1.
RefSeqYP_001969326.1. NC_010939.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB3H2F9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6397647.
GenomeReviewsGene locus APP7_1532 in contig CP001091_GR.
KEGGapa:APP7_1532.
PATRIC20756778. VBIActPle116979_1566.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG302256.
OMASMATVWH.
ProtClustDBPRK00044.

Family and domain databases

HAMAPMF_00662. PS_decarb_type1.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
KOK01613.
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_ACTP7
AccessionPrimary (citable) accession number: B3H2F9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 22, 2008
Last modified: January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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