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B3H2E6 (MQO_ACTP7) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4
Alternative name(s):
MQO
Malate dehydrogenase [quinone]
Gene names
Name:mqo
Ordered Locus Names:APP7_1519
OrganismActinobacillus pleuropneumoniae serotype 7 (strain AP76) [Complete proteome] [HAMAP]
Taxonomic identifier537457 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length491 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212

Cofactor

FAD By similarity. HAMAP MF_00212

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212

Sequence similarities

Belongs to the MQO family.

Ontologies

Keywords
   Biological processTricarboxylic acid cycle
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmalate dehydrogenase (menaquinone) activity

Inferred from electronic annotation. Source: EC

malate dehydrogenase (quinone) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 491491Probable malate:quinone oxidoreductase HAMAP MF_00212
PRO_1000099866

Sequences

Sequence LengthMass (Da)Tools
B3H2E6 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: 48A0BA8B61750E27

FASTA49154,075
        10         20         30         40         50         60 
MQDSSSALES YSDVTLIGAG IMSGTLGAFL TELAPEKSLA IFEKLSAVGL ESSNEWNNAG 

        70         80         90        100        110        120 
TGHSALCELN YTEQKADGEV SVERAVKICE DFQLSLQLWS YLVETGRIQA PREFIHRIPH 

       130        140        150        160        170        180 
ISFVQGEQNA QFLQKRYQSL AQSHLFEGMQ FSRDHQQLAQ WMPLMMQNRD SNETLAASYI 

       190        200        210        220        230        240 
QYGTDVNFGE LTRKLFDYLV KQKAELNLNH TVKNIQRLAN GEWKLTVVDQ QGQKRVHRSK 

       250        260        270        280        290        300 
FVFIGGGGGA LPLLQKSGIT DGKNVGGFPV SGLFMVCNNP EVIAKHNAKV YGKAKLGAPP 

       310        320        330        340        350        360 
MSVPHLDTRF IEGKQSLLFG PFAGFTLKFL KQGSVLDLPT SVTPTNFCSV TKAGIKNLPL 

       370        380        390        400        410        420 
AHYLMKQAML TKAQRMADLR EFVPDAKDED WDVVVAGQRV QVIKGGEMRF GTEVIRAEDG 

       430        440        450        460        470        480 
SLAALLGASP GASTSVKAML DVLVSCFAAE LPQWQAKLTQ MLPSYGKALR NEPQLYAQIK 

       490 
QRVDQVLALA N

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References

[1]"Genome and proteome analysis of A. pleuropneumoniae serotype 7."
Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N., Tegetmeyer H., Singh M., Gerlach G.F.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AP76.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001091 Genomic DNA. Translation: ACE62171.1.
RefSeqYP_001969313.1. NC_010939.1.

3D structure databases

ProteinModelPortalB3H2E6.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3H2E6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6396782.
GenomeReviewsGene locus APP7_1519 in contig CP001091_GR.
KEGGapa:APP7_1519.
PATRIC20756750. VBIActPle116979_1552.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG289663.
OMAKKWVPLM.
ProtClustDBPRK05257.

Family and domain databases

HAMAPMF_00212. MQO.
[Tree]
InterProIPR006231. Malate_quinone_OxRdtase.
[Graphical view]
KOK00116.
PANTHERPTHR13847:SF14. PTHR13847:SF14. 1 hit.
PfamPF06039. Mqo. 1 hit.
[Graphical view]
TIGRFAMsTIGR01320. Mal_quin_oxido. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMQO_ACTP7
AccessionPrimary (citable) accession number: B3H2E6
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 22, 2008
Last modified: January 25, 2012
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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