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B3H222

- PGK_ACTP7

UniProt

B3H222 - PGK_ACTP7

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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Actinobacillus pleuropneumoniae serotype 7 (strain AP76)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei36 – 361SubstrateUniRule annotation
Binding sitei114 – 1141SubstrateUniRule annotation
Binding sitei147 – 1471SubstrateUniRule annotation
Binding sitei198 – 1981ATPUniRule annotation
Binding sitei315 – 3151ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi344 – 3474ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAPLE537457:GJI0-1326-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:APP7_1300
OrganismiActinobacillus pleuropneumoniae serotype 7 (strain AP76)
Taxonomic identifieri537457 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
ProteomesiUP000001226: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 391391Phosphoglycerate kinasePRO_1000096316Add
BLAST

Proteomic databases

PRIDEiB3H222.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi537457.APP7_1300.

Structurei

3D structure databases

ProteinModelPortaliB3H222.
SMRiB3H222. Positions 2-389.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate bindingUniRule annotation
Regioni59 – 624Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiAGHPVGK.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.

Sequencei

Sequence statusi: Complete.

B3H222-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSVIKMADLD LAGKRLFIRA DLNVPVKDGK VTSDARIRAT IPTLKLALQK
60 70 80 90 100
GAKVMVTSHL GRPTEGVFEE ANSLQPVVDY LNASDLGVPV RLVRDYLDGV
110 120 130 140 150
EVAENEIVVL ENVRINKGEK KNDPELAKKY AALCDVFVMD AFGTAHRAEG
160 170 180 190 200
STYGVAEYAP VACAGPLLAA ELDALGKALK EPQRPMLAIV GGSKVSTKLT
210 220 230 240 250
VLDSLSKIAD QLIVGGGIAN TFIAAEGHPV GKSLYEADLI PEAKRLAAAT
260 270 280 290 300
NIPVPVDVRV GTEFSEIAPA TEKAVSEVQA DESIFDIGDK SAEELANIIK
310 320 330 340 350
SAKTILWNGP VGVFEFPNFR KGTEVISNAI AEATANGAFS IAGGGDTLAA
360 370 380 390
IDLFGIADKI SYISTGGGAF LEFVEGKVLP AVEILEKRAN G
Length:391
Mass (Da):41,170
Last modified:July 22, 2008 - v1
Checksum:i88042F440E009A86
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001091 Genomic DNA. Translation: ACE61952.1.
RefSeqiYP_001969094.1. NC_010939.1.

Genome annotation databases

EnsemblBacteriaiACE61952; ACE61952; APP7_1300.
GeneIDi6396177.
KEGGiapa:APP7_1300.
PATRICi20756263. VBIActPle116979_1329.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001091 Genomic DNA. Translation: ACE61952.1 .
RefSeqi YP_001969094.1. NC_010939.1.

3D structure databases

ProteinModelPortali B3H222.
SMRi B3H222. Positions 2-389.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 537457.APP7_1300.

Proteomic databases

PRIDEi B3H222.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACE61952 ; ACE61952 ; APP7_1300 .
GeneIDi 6396177.
KEGGi apa:APP7_1300.
PATRICi 20756263. VBIActPle116979_1329.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi AGHPVGK.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci APLE537457:GJI0-1326-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome and proteome analysis of A. pleuropneumoniae serotype 7."
    Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N., Tegetmeyer H., Singh M., Gerlach G.F.
    Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AP76.

Entry informationi

Entry nameiPGK_ACTP7
AccessioniPrimary (citable) accession number: B3H222
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 22, 2008
Last modified: October 29, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3