ID   B3H1S4_ACTP7            Unreviewed;       405 AA.
AC   B3H1S4;
DT   22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2008, sequence version 1.
DT   27-MAR-2024, entry version 67.
DE   RecName: Full=alanine transaminase {ECO:0000256|ARBA:ARBA00026106};
DE            EC=2.6.1.2 {ECO:0000256|ARBA:ARBA00026106};
GN   OrderedLocusNames=APP7_1099 {ECO:0000313|EMBL:ACE61751.1};
OS   Actinobacillus pleuropneumoniae serotype 7 (strain AP76).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Actinobacillus.
OX   NCBI_TaxID=537457 {ECO:0000313|EMBL:ACE61751.1, ECO:0000313|Proteomes:UP000001226};
RN   [1] {ECO:0000313|Proteomes:UP000001226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AP76 {ECO:0000313|Proteomes:UP000001226};
RA   Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N.,
RA   Tegetmeyer H., Singh M., Gerlach G.F.;
RT   "Genome and proteome analysis of A. pleuropneumoniae serotype 7.";
RL   Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the class-I pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|ARBA:ARBA00007441}.
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DR   EMBL; CP001091; ACE61751.1; -; Genomic_DNA.
DR   RefSeq; WP_012478476.1; NC_010939.1.
DR   AlphaFoldDB; B3H1S4; -.
DR   KEGG; apa:APP7_1099; -.
DR   HOGENOM; CLU_017584_4_2_6; -.
DR   Proteomes; UP000001226; Chromosome.
DR   GO; GO:0004069; F:L-aspartate:2-oxoglutarate aminotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00609; AAT_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR43488; GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA; 1.
DR   PANTHER; PTHR43488:SF2; GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Aminotransferase {ECO:0000313|EMBL:ACE61751.1};
KW   Transferase {ECO:0000313|EMBL:ACE61751.1}.
FT   DOMAIN          34..395
FT                   /note="Aminotransferase class I/classII"
FT                   /evidence="ECO:0000259|Pfam:PF00155"
SQ   SEQUENCE   405 AA;  45386 MW;  50A2BA261D5BEAF2 CRC64;
     MERFPKSDKL ANVRYDIRGA IHKEALRLEE EGNKILKLNI GNPAPFGFEA PDEIVVDVIR
     NLPKSQGYCD SKGLYSARKA VVQYYQSKGI RNVDVNDVYI GNGVSELITM SMQALLNDGD
     EMLIPMPDYP LWTAAATLAG GKAVHYLCDE NNEWMPDIED IKAKITPRTK GILVINPNNP
     TGAVYSRSML LEIAEIARQH NLMIFADEIY EKIIYDGAVH HHIAALAPDL LCVTYNGLSK
     AYRVAGFRQG WMVLSGPKNQ AKGFIEGLEM LASMRLCATT PMQHAIQTAL GGYQSINEFV
     LPGGRLLEQR NKMYELLVQI PGISCVKAKG ALYMFPKIDT EMYGIKDDAK FIYDLLQAER
     VLLVQGSGFN WHKPDHFRVV TLPYAHQIEE ALGRLANFLK TYKQS
//