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B3H1P7 (DEOC_ACTP7) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Deoxyribose-phosphate aldolase
Short name=DERA
EC=4.1.2.4
Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase
Phosphodeoxyriboaldolase
Short name=Deoxyriboaldolase
Gene names
Name:deoC
Ordered Locus Names:APP7_1072
OrganismActinobacillus pleuropneumoniae serotype 7 (strain AP76) [Complete proteome] [HAMAP]
Taxonomic identifier537457 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length258 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP MF_00592

Catalytic activity

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00592

Pathway

Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00592

Subcellular location

Cytoplasm By similarity HAMAP MF_00592.

Sequence similarities

Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandSchiff base
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processdeoxyribonucleotide catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondeoxyribose-phosphate aldolase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 258258Deoxyribose-phosphate aldolase HAMAP MF_00592
PRO_1000129796

Sites

Active site1661Schiff-base intermediate with acetaldehyde By similarity
Active site2001 By similarity

Sequences

Sequence LengthMass (Da)Tools
B3H1P7 [UniParc].

Last modified July 22, 2008. Version 1.
Checksum: 7F8E870A78C01245

FASTA25827,605
        10         20         30         40         50         60 
MSLKDSAKIA LSLMDLTTLN DNDTDEKVIT LCQQGKTEFG TPAAVCVYPR FVPIARKALK 

        70         80         90        100        110        120 
AQGTEQVKIA TVTNFPHGND DIDIAVAETK AAVAYGADEV DVVFPYKALM AGNEQIGFEL 

       130        140        150        160        170        180 
VQQCKAVCQA SNVLLKVIIE TGELKTAELI RKASEISIKA GADFIKTSTG KVPVNATLES 

       190        200        210        220        230        240 
ARIMLETIRD LNVADRVGFK AAGGVKTAEE AAQYLALAQE ILGHDWVNSD HFRFGASSLL 

       250 
TNLLAALNGQ ANQKVSGY

« Hide

References

[1]"Genome and proteome analysis of A. pleuropneumoniae serotype 7."
Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N., Tegetmeyer H., Singh M., Gerlach G.F.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AP76.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001091 Genomic DNA. Translation: ACE61724.1.
RefSeqYP_001968866.1. NC_010939.1.

3D structure databases

ProteinModelPortalB3H1P7.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3H1P7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6397191.
GenomeReviewsGene locus APP7_1072 in contig CP001091_GR.
KEGGapa:APP7_1072.
PATRIC20755784. VBIActPle116979_1094.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG636421.
OMAELVQQCK.
ProtClustDBPRK05283.

Family and domain databases

HAMAPMF_00592. DeoC_type2.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/AroFGH_arch.
IPR023649. DeoC_bac.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01619.
PANTHERPTHR10889. DeoC. 1 hit.
PfamPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFPIRSF001357. DeoC. 1 hit.
TIGRFAMsTIGR00126. DeoC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDEOC_ACTP7
AccessionPrimary (citable) accession number: B3H1P7
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 22, 2008
Last modified: January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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