B3H1H2 (DCD_ACTP7) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	APP7_0892

Organism

Actinobacillus pleuropneumoniae serotype 7 (strain AP76) [Complete proteome] [HAMAP]

Taxonomic identifier

537457 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length	194 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 194	194	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000096403

Sequences

	Sequence		Length	Mass (Da)
	B3H1H2 [UniParc]. Last modified July 22, 2008. Version 1. Checksum: F3E7DD3222E34047	FASTA	194	21,476
	10 20 30 40 50 60 MRLCDTDIER YLDEGIIEII PRPSNEKITG ATVDVRLGNS FRVFREHATP YIDLSGPREE 70 80 90 100 110 120 VTAQLHKVMS EEIIIADGEA FFLHPGELAL ATTLESVTLP DNVVGWLDGR SSLARLGLMV 130 140 150 160 170 180 HVTAHRIDPG WQGKIVLEFF NAGKLPLALR PNMAIGALSF EILSGHAAKP YNARKDAKYK 190 NQQSAVSSRI NQDD

References

[1]	"Genome and proteome analysis of A. pleuropneumoniae serotype 7." Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N., Tegetmeyer H., Singh M., Gerlach G.F. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AP76.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001091 Genomic DNA. Translation: ACE61544.1.
RefSeq	YP_001968686.1. NC_010939.1.
3D structure databases
ProteinModelPortal	B3H1H2.
SMR	B3H1H2. Positions 1-193.
ModBase	Search...
Protein-protein interaction databases
STRING	B3H1H2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6395895.
GenomeReviews	Gene locus APP7_0892 in contig CP001091_GR.
KEGG	apa:APP7_0892.
PATRIC	20755419. VBIActPle116979_0914.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG553199.
OMA	HTAAYID.
ProtClustDB	PRK00416.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_ACTP7

Accession

Primary (citable) accession number: B3H1H2

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	July 22, 2008
Last modified:	January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program