B3H1B8 (LOLB_ACTP7) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Outer-membrane lipoprotein LolB

Gene names

Name:	lolB
Ordered Locus Names:	APP7_0838

Organism

Actinobacillus pleuropneumoniae serotype 7 (strain AP76) [Complete proteome] [HAMAP]

Taxonomic identifier

537457 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus › Actinobacillus pleuropneumoniae › Actinobacillus pleuropneumoniae serovar 7

Protein attributes

Sequence length	210 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein By similarity. HAMAP-Rule MF_00233
Subunit structure	Monomer By similarity.
Subcellular location	Cell outer membrane; Lipid-anchor By similarity HAMAP-Rule MF_00233.
Sequence similarities	Belongs to the LolB family.

Ontologies

Keywords
Biological process	Protein transport Transport
Cellular component	Cell membrane Cell outer membrane Membrane
Domain	Signal
Molecular function	Chaperone
PTM	Lipoprotein Palmitate
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	cell outer membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	protein transporter activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 18	18	Potential
	Chain	19 – 210	192	Outer-membrane lipoprotein LolB HAMAP-Rule MF_00233		PRO_1000100489
Amino acid modifications
	Lipidation	19	1	N-palmitoyl cysteine Potential
	Lipidation	19	1	S-diacylglycerol cysteine Potential

Sequences

	Sequence		Length	Mass (Da)
	B3H1B8 [UniParc]. Last modified July 22, 2008. Version 1. Checksum: 8808B6B2189189E2	FASTA	210	24,155
	10 20 30 40 50 60 MKKFTKILSL STLLFLAGCQ SVLNEPTEVQ QPGVQIPHND AQWQQHLQQL AKIQSYSAKG 70 80 90 100 110 120 QIGYISPEER FSSHFDWQYR TPTNFGLELS SNLSSKSLKL QRNARGLTIS DSEGNSRSDR 130 140 150 160 170 180 DMDSLMKEII GVAFPIDQFA YWLKGQPEQD GNYIVNDKRQ LSQFSYHING EVWKASYVQY 190 200 210 HEDRQPNLPK LIVLENGSQT LKIRVDQWAF

References

[1]	"Genome and proteome analysis of A. pleuropneumoniae serotype 7." Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N., Tegetmeyer H., Singh M., Gerlach G.F. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AP76.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001091 Genomic DNA. Translation: ACE61490.1.
RefSeq	YP_001968632.1. NC_010939.1.
3D structure databases
ProteinModelPortal	B3H1B8.
ModBase	Search...
Protein-protein interaction databases
STRING	537457.APP7_0838.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACE61490; ACE61490; APP7_0838.
GeneID	6396233.
KEGG	apa:APP7_0838.
PATRIC	20755303. VBIActPle116979_0858.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3017.
HOGENOM	HOG000263563.
KO	K02494.
OMA	WLQRQDY.
ProtClustDB	PRK00022.
Enzyme and pathway databases
BioCyc	APLE537457:GJI0-856-MONOMER.
Family and domain databases
HAMAP	MF_00233. LolB.
InterPro	IPR004565. OM_lipoprot_LolB. [Graphical view]
Pfam	PF03550. LolB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00548. lolB. 1 hit.
PROSITE	PS51257. PROKAR_LIPOPROTEIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LOLB_ACTP7

Accession

Primary (citable) accession number: B3H1B8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	July 22, 2008
Last modified:	May 1, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program