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Protein

1,4-alpha-glucan branching enzyme GlgB

Gene

glgB

Organism
Actinobacillus pleuropneumoniae serotype 7 (strain AP76)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei408NucleophileUniRule annotation1
Active sitei461Proton donorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCarbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

UniPathwayiUPA00164

Protein family/group databases

CAZyiCBM48 Carbohydrate-Binding Module Family 48
GH13 Glycoside Hydrolase Family 13

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgBUniRule annotation (EC:2.4.1.18UniRule annotation)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferaseUniRule annotation
Alpha-(1->4)-glucan branching enzymeUniRule annotation
Glycogen branching enzymeUniRule annotation
Short name:
BEUniRule annotation
Gene namesi
Name:glgBUniRule annotation
Ordered Locus Names:APP7_0351
OrganismiActinobacillus pleuropneumoniae serotype 7 (strain AP76)
Taxonomic identifieri537457 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
Proteomesi
  • UP000001226 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001318051 – 7771,4-alpha-glucan branching enzyme GlgBAdd BLAST777

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB3H0J1
SMRiB3H0J1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000283037
KOiK00700
OMAiEVVHGKS
OrthoDBiPOG091H08D1

Family and domain databases

Gene3Di2.60.40.101 hit
2.60.40.11801 hit
HAMAPiMF_00685 GlgB, 1 hit
InterProiView protein in InterPro
IPR006048 A-amylase/branching_C
IPR037439 Branching_enzy
IPR006407 GlgB
IPR006047 Glyco_hydro_13_cat_dom
IPR004193 Glyco_hydro_13_N
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
PANTHERiPTHR43651 PTHR43651, 1 hit
PfamiView protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF02806 Alpha-amylase_C, 1 hit
PF02922 CBM_48, 1 hit
PIRSFiPIRSF000463 GlgB, 1 hit
SMARTiView protein in SMART
SM00642 Aamy, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
SSF81296 SSF81296, 2 hits
TIGRFAMsiTIGR01515 branching_enzym, 1 hit

Sequencei

Sequence statusi: Complete.

B3H0J1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTYTYSKQD LSFIEQLSQA YCKDPFSYLG LHQAGDVSVI RVFLPEATTV
60 70 80 90 100
KILSADGQIL SEALKIDDSG LFVAQLSQQY SSLNYRLRVG YSLAEIDLED
110 120 130 140 150
PYRFTSSLLP MDNWLLAEGT HLRPYEILGA HLKTQEGVSG VHFSVWAPNA
160 170 180 190 200
RRVSVVGDFN YWDGRVNPMR FHAESGIWDI FLPNVEKGAL YKFEILDSNG
210 220 230 240 250
NIRLKSDPYA FASQFRPDTA SVVTGLPEKI EVDAKLRHAN DPDQPISIYE
260 270 280 290 300
VHLGSWRRHL ENNYWLNYEE IANELIPYVK DMGFTHIELL PITEYPFDGS
310 320 330 340 350
WGYQPTGLYS PTSRFGSPDD LRTLIRKAHE AGINVILDWV VGHFPTDSHG
360 370 380 390 400
LTEFDGSHLY EHQDPREGYH QDWNTLIFNY GRHEVFNYLS SNALYWTERF
410 420 430 440 450
GIDGLRVDAV SSMIYRDYSR KDGEWIPNQY GGRENLEALD FLRRTNRMLK
460 470 480 490 500
KEGHGAVVIA EESTSFAGIT HSPTENGVGF DYKWNMGWMN DTLRYMSLDP
510 520 530 540 550
IYRQYHHDWM TFGMMYQYSE KFVLPLSHDE VVHGKCSILG KMSGDCWQKF
560 570 580 590 600
ANLRAYYGYM WGYPGKKLLF MGNEFAQGRE WNYNESLDWF LLGEQGGGWH
610 620 630 640 650
KGVLNWVRDL NRTYQKYPAL YQLDYDPAGF EWLVVDDWQQ SVFAFERKAK
660 670 680 690 700
NGESVIVVSN FTPVVRHNYR IGVRQDGTYT EILNSDAAYY EGSNVGNYGE
710 720 730 740 750
IECEAIESHG KPFSIELSIP PLSTIFIACQ PKPKEAVEAE QDIVKMAEVA
760 770
MQKALKPTKK TVSVKAKAHK KAHKNKK
Length:777
Mass (Da):89,290
Last modified:July 22, 2008 - v1
Checksum:i721D6F0872F6BA8B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001091 Genomic DNA Translation: ACE61003.1
RefSeqiWP_005616806.1, NC_010939.1

Genome annotation databases

EnsemblBacteriaiACE61003; ACE61003; APP7_0351
KEGGiapa:APP7_0351

Similar proteinsi

Entry informationi

Entry nameiGLGB_ACTP7
AccessioniPrimary (citable) accession number: B3H0J1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 22, 2008
Last modified: February 28, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome