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B3H0I4

- B3H0I4_ACTP7

UniProt

B3H0I4 - B3H0I4_ACTP7

Protein

Phosphoenolpyruvate carboxylase

Gene

pepC

Organism
Actinobacillus pleuropneumoniae serotype 7 (strain AP76)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 1 (22 Jul 2008)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei138 – 1381UniRule annotation
    Active sitei545 – 5451UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciAPLE537457:GJI0-355-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:pepCImported
    Synonyms:ppcUniRule annotation
    Ordered Locus Names:APP7_0344Imported
    OrganismiActinobacillus pleuropneumoniae serotype 7 (strain AP76)Imported
    Taxonomic identifieri537457 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
    ProteomesiUP000001226: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi537457.APP7_0344.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2352.
    HOGENOMiHOG000238648.
    KOiK01595.
    OMAiELSTISC.
    OrthoDBiEOG6TJ7T8.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B3H0I4-1 [UniParc]FASTAAdd to Basket

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    MNQPYSAMRN NIHMLGDFLG ETIREAQGNE ILELIESIRV LSRDSRAGDE    50
    KAREQLLDKL ANISTENVLP VARAFSQFLN LTNIAEQYQT ISRHHQDESL 100
    GNRSLSALFA RLKAQGTPVE TVIKTVEKLL IELVLTAHPT EVTRRSLVHK 150
    HVEINKCLGQ LEHDDLTEAE QTKLKRRLMQ LIALAWHTNE IRAARPTPVD 200
    EAKWGMAIIE NSLWKAVPDF CRELNFQLEK HFDVQYEVAL SPVRFSSWMG 250
    GDRDGNPFVT AEITQKVLRM NRWKAAELFL NDVSDLVEEL SIVQCTPEFR 300
    EKYGDHIEPY RVVVKGLRSK LQKTLTYFGE LIEAKPTTVD PSEIITCDND 350
    LWEPLYDCYQ SLHACGMRII ANGSLLDCLR RIRCFGLGLS RLDIRQESSR 400
    HETAIAEITR YIGLGDYAQW TEDDKQAFLV RELSSRRPLV PTNWTPSPET 450
    QEILDTCKVV AQQPEGTISA YVISMAREAS DVLAVHLLLK EAGCNYTLPV 500
    APLFETLDDL DHSEKVMTDL FNIGWYRGVI NNYQMVMIGY SDSAKDAGML 550
    AASWAQYRAQ EALVNLAEKY HIELVLFHGR GGTVGRGGAP AHAALLSQPP 600
    RSLKSGLRVT EQGEMIRFKL GLPAVAVETL NLYASAILEA NLLPPPEPKQ 650
    KWRDIMDKGA AISCEIYRGV VRGEPDFVPY FRSATPEQEL GKLPLGSRPS 700
    KRNPNGGVES LRAIPWIFAW MQNRLMLPAW LGAGAALRQM IEQGEESTLK 750
    EMCNEWPFFS TRIGMLEMVF SKADLWLAEH YDQRLVAKEL HRLGKTLRAQ 800
    LSADIQTVLT LAHDGQLMAD LPWIAESIAL RNVYTDPLNL LQVELLQRLR 850
    SQGEVRDPQL EQALMITITG IAAGMRNTG 879
    Length:879
    Mass (Da):99,170
    Last modified:July 22, 2008 - v1
    Checksum:iB40E41DCC8AC2C4C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001091 Genomic DNA. Translation: ACE60996.1.
    RefSeqiYP_001968138.1. NC_010939.1.

    Genome annotation databases

    EnsemblBacteriaiACE60996; ACE60996; APP7_0344.
    GeneIDi6396948.
    KEGGiapa:APP7_0344.
    PATRICi20754279. VBIActPle116979_0354.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001091 Genomic DNA. Translation: ACE60996.1 .
    RefSeqi YP_001968138.1. NC_010939.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 537457.APP7_0344.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACE60996 ; ACE60996 ; APP7_0344 .
    GeneIDi 6396948.
    KEGGi apa:APP7_0344.
    PATRICi 20754279. VBIActPle116979_0354.

    Phylogenomic databases

    eggNOGi COG2352.
    HOGENOMi HOG000238648.
    KOi K01595.
    OMAi ELSTISC.
    OrthoDBi EOG6TJ7T8.

    Enzyme and pathway databases

    BioCyci APLE537457:GJI0-355-MONOMER.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome and proteome analysis of A. pleuropneumoniae serotype 7."
      Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N., Tegetmeyer H., Singh M., Gerlach G.F.
      Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AP76Imported.

    Entry informationi

    Entry nameiB3H0I4_ACTP7
    AccessioniPrimary (citable) accession number: B3H0I4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 22, 2008
    Last sequence update: July 22, 2008
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3