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B3H0I4

- B3H0I4_ACTP7

UniProt

B3H0I4 - B3H0I4_ACTP7

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Protein
Phosphoenolpyruvate carboxylase
Gene
pepC, ppc, APP7_0344
Organism
Actinobacillus pleuropneumoniae serotype 7 (strain AP76)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381 By similarityUniRule annotation
Active sitei545 – 5451 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciAPLE537457:GJI0-355-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:pepCImported
Synonyms:ppcUniRule annotation
Ordered Locus Names:APP7_0344Imported
OrganismiActinobacillus pleuropneumoniae serotype 7 (strain AP76)Imported
Taxonomic identifieri537457 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
ProteomesiUP000001226: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi537457.APP7_0344.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiELSTISC.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3H0I4-1 [UniParc]FASTAAdd to Basket

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MNQPYSAMRN NIHMLGDFLG ETIREAQGNE ILELIESIRV LSRDSRAGDE    50
KAREQLLDKL ANISTENVLP VARAFSQFLN LTNIAEQYQT ISRHHQDESL 100
GNRSLSALFA RLKAQGTPVE TVIKTVEKLL IELVLTAHPT EVTRRSLVHK 150
HVEINKCLGQ LEHDDLTEAE QTKLKRRLMQ LIALAWHTNE IRAARPTPVD 200
EAKWGMAIIE NSLWKAVPDF CRELNFQLEK HFDVQYEVAL SPVRFSSWMG 250
GDRDGNPFVT AEITQKVLRM NRWKAAELFL NDVSDLVEEL SIVQCTPEFR 300
EKYGDHIEPY RVVVKGLRSK LQKTLTYFGE LIEAKPTTVD PSEIITCDND 350
LWEPLYDCYQ SLHACGMRII ANGSLLDCLR RIRCFGLGLS RLDIRQESSR 400
HETAIAEITR YIGLGDYAQW TEDDKQAFLV RELSSRRPLV PTNWTPSPET 450
QEILDTCKVV AQQPEGTISA YVISMAREAS DVLAVHLLLK EAGCNYTLPV 500
APLFETLDDL DHSEKVMTDL FNIGWYRGVI NNYQMVMIGY SDSAKDAGML 550
AASWAQYRAQ EALVNLAEKY HIELVLFHGR GGTVGRGGAP AHAALLSQPP 600
RSLKSGLRVT EQGEMIRFKL GLPAVAVETL NLYASAILEA NLLPPPEPKQ 650
KWRDIMDKGA AISCEIYRGV VRGEPDFVPY FRSATPEQEL GKLPLGSRPS 700
KRNPNGGVES LRAIPWIFAW MQNRLMLPAW LGAGAALRQM IEQGEESTLK 750
EMCNEWPFFS TRIGMLEMVF SKADLWLAEH YDQRLVAKEL HRLGKTLRAQ 800
LSADIQTVLT LAHDGQLMAD LPWIAESIAL RNVYTDPLNL LQVELLQRLR 850
SQGEVRDPQL EQALMITITG IAAGMRNTG 879
Length:879
Mass (Da):99,170
Last modified:July 22, 2008 - v1
Checksum:iB40E41DCC8AC2C4C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001091 Genomic DNA. Translation: ACE60996.1.
RefSeqiYP_001968138.1. NC_010939.1.

Genome annotation databases

EnsemblBacteriaiACE60996; ACE60996; APP7_0344.
GeneIDi6396948.
KEGGiapa:APP7_0344.
PATRICi20754279. VBIActPle116979_0354.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001091 Genomic DNA. Translation: ACE60996.1 .
RefSeqi YP_001968138.1. NC_010939.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 537457.APP7_0344.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACE60996 ; ACE60996 ; APP7_0344 .
GeneIDi 6396948.
KEGGi apa:APP7_0344.
PATRICi 20754279. VBIActPle116979_0354.

Phylogenomic databases

eggNOGi COG2352.
HOGENOMi HOG000238648.
KOi K01595.
OMAi ELSTISC.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci APLE537457:GJI0-355-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome and proteome analysis of A. pleuropneumoniae serotype 7."
    Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N., Tegetmeyer H., Singh M., Gerlach G.F.
    Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AP76.

Entry informationi

Entry nameiB3H0I4_ACTP7
AccessioniPrimary (citable) accession number: B3H0I4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: June 11, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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